Need Help?

WGS data of non-small cell lung cancer samples

Paired-end WGS data from 118 non-small cell lung cancer samples from 49 patients. WGS was performed on Illumina NovaSeq 6000.

Request Access

DAP for "Copy number variations and fragmentation features in cell-free DNA predict response in advanced non-small cell lung cancer patients under anti-PD-(L)1 therapy"

Data Transfer Agreement of Human Genomic Data for Research Purposes Between: (1) Deutsches Krebsforschungszentrum (DKFZ), Stiftung des öffentlichen Rechts, legally represented by its Management Board , Prof. Dr. med. Michael Baumann and Ursula Weyrich Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany (“PROVIDER“) and (2) [INSERT INSTITUTION DETAILS] (“RECIPIENT”). 1 Preamble Public genetic sequence databases are a critical part of our academic biomedical research infrastructure. However, human genetic data should only be made public if we can adequately protect the privacy of research subjects. Individual genomic sequence data are sensitive patient data and any attempt to re-identify such data is forbidden under any circumstances. Our efforts to understand disease susceptibility or therapeutic opportunity require access to large genomic data sets. Therefore, the special privacy challenges posed by genomic data are addressed by PROVIDER with this Agreement. In response to the RECIPIENT's request for access to the DATA (as defined below), PROVIDER and the RECIPIENT agree as follows: 2 Definitions “DATA” shall mean all and any human genetic data obtained by the RECIPIENT from the PROVIDER including the Data Subjects’ e.g. age, sex and tumor pathology (as listed in Annex 2). For the avoidance of doubt, Data does not include samples or biological materials; “DATA SUBJECT” shall mean the person (irrespective of the state of health) to whom Data refers and who has been informed of the purpose for which the Data is held and has given his/her informed consent thereto; “COMMERCIAL PURPOSES” shall mean the sale, lease, license, or other transfer and/or the use of the DATA to and/or by a for-profit organization. However, industrially sponsored academic research shall not be considered a use of the DATA for Commercial Purposes per se. “INTELLECTUAL PROPERTY” shall mean (i) patents, designs, trademarks and trade names (whether registered or unregistered), copyright and related rights, database rights, know-how and confidential information; (ii) all other intellectual property rights and similar or equivalent rights (whether registered or unregistered and whether registrable or unregistrable) anywhere in the world which currently exist or are recognized in the future; and (iii) applications, extensions and renewals in relation to any such rights; “RECIPIENT SCIENTIST” shall mean a researcher (or an individual conducting Research under the supervision of a researcher) that is employed by the RECIPIENT and is bound by confidentiality and non-use obligations in respect of DATA and who has accepted the terms of this Agreement in writing (however, for the avoidance of doubt, without being a party to this Agreement) and has received acknowledgement of its acceptance. For the avoidance of doubt and without having explicitly accepted the terms of this Agreement in writing, “RECIPIENT SCIENTIST” may also include any other RECIPIENT’s employees, students, visiting academics, contractors, sub-contractors or independent consultants provided that any of such latter individuals is bound by confidentiality and non- use obligations no less onerous than those binding the RECIPIENT’s employees; “RESEARCH” shall mean research that is seeking to advance the understanding and treatment of cancer and closely related diseases, and work on statistical methods that may be applied to such research; “PROJECT” shall mean a detailed description as in Annex 3; 3 Purpose of the Project The RECIPIENT agrees to use DATA only for RESEARCH as described in the purpose of the PROJECT (Annex 3). 4 Confidentiality The RECIPIENT agrees to preserve, at all times, the confidentiality of DATA pertaining to DATA SUBJECTs. In particular, the RECIPIENT undertakes not to use, or attempt to use the DATA to deliberately compromise or otherwise infringe the confidentiality of information on DATA SUBJECTs and their respective rights to privacy. 5 DATA Protection The Recipient and its RECIPIENT SCIENTIST are covered by and the RECIPIENT shall, and shall procure that its RECIPIENT SCIENTISTS shall, comply with the obligations contained in the applicable German and EU data protection laws and regulations as amended from time to time. In particular, the RECIPIENT and its RECIPIENT SCIENTISTs inter alia understands, and shall procure that its RECIPIENT SCIENTISTs understand, their duties under the German and EU legislation in relation to the handling of DATA and the rights of DATA SUBJECTs. The RECIPIENT agrees that it, and its RECIPIENT SCIENTISTs, shall not analyze or make any use of the DATA in such a way that has the potential to: a) lead to the re-identification of any DATA SUBJECT; or b) compromise the anonymity of any DATA SUBJECT in any way. The RECIPIENT shall, and it shall procure that its RECIPIENT SCIENTISTS shall, adhere to the principles of IT-Security as set forth in Annex 1 hereto. 6 Access and Governance The RECIPIENT agrees that it shall take all (commercially) reasonable security precautions to keep the DATA confidential, such precautions to be no less onerous than in the applicable German and EU data protection laws and regulations. The RECIPIENT agrees to use the DATA solely for RESEARCH in the frame of the purpose of the PROJECT. The RECIPIENT agrees that the DATA shall not be distributed or released to any other location and/or to any other person other than RECIPIENT SCIENTISTs or laboratory personnel under the RECIPIENT SCIENTISTs direct supervision. RECIPIENT does not have the right to sublicense the DATA. RECIPIENT shall inform PROVIDER about any third party requests for the DATA. PROVIDER reserves the right to request and inspect DATA security and management documentation at the RECIPIENT’s premises to ensure the adequacy of DATA protection measures with prior notice during the RECIPIENT’s ordinary working hours. DATA shall not be used for COMMERCIAL PURPOSES (e.g. diagnostic services). In case of intended commercial use of DATA, the RECIPIENT shall start negotiations in good faith leading to a fair market compensation of PROVIDER. Such a disclosure of DATA shall require a binding declaration of consent in writing from the person concerned. 7 Errors The RECIPIENT agrees to notify the PROVIDER of any errors detected in the DATA without undue delay. 8 DATA reissue The RECIPIENT accepts that PROVIDER will reissue DATA from time to time, with suitable versioning. If DATA is reissued at the request of the DATA SUBJECT and/or as the result of other ethical scrutiny, the RECIPIENT agrees to destroy all earlier versions of the DATA without undue delay once he has received such information. This shall not apply to the extent that DATA is saved in automatic back-up systems for which destruction shall follow the regular process of such back-up system, however, such DATA shall be eliminated within a period of four (4) weeks after reception of the respective request to do so or within a period of four (4) weeks upon termination in accordance with this Agreement. 9 INTELLECTUAL PROPERTY The RECIPIENT recognizes that nothing in this Agreement shall operate to transfer to the RECIPIENT or its RECIPIENT SCIENTISTs any INTELLECTUAL PROPERTY rights in or relating to the DATA, i.e. ownership of DATA remains unchanged. The RECIPIENT does not have the right to sublicense the DATA. The RECIPIENT shall inform PROVIDER about any third party requests for the DATA. In case the RECIPIENT and its RECIPIENT SCIENTISTs develops INTELLECTUAL PROPERTY based on or related to DATA as set forth in this Agreement the RECIPIENT shall become owner of such results. The RECIPIENT will inform PROVIDER about all developed INTELLECTUAL PROPERTY based on or related to DATA as set forth in this Agreement without undue delay in writing. The RECIPIENT grants PROVIDER a non-exclusive, non-transferable, royalty-free, perpetual, non-sublicensable right to use such developed INTELLECTUAL PROPERTY for internal research purposes including collaborations with any third parties excluding any COMMERCIAL PURPOSES. 10 Publications The RECIPIENT agrees to acknowledge in any RECIPIENT’s work based in whole or part on the DATA, any PROVIDER publications which encompass and from which DATA derive, the respective version of the DATA obtained, and the role of PROVIDER. The RECIPIENT is also entitled to release publications and, in doing so, agrees to acknowledge any of PROVIDER’s work based in whole or part on the DATA in its publication. The RECIPIENT will also declare in any such work that PROVIDER and its employees bear no responsibility for the further analysis or interpretation of the DATA by the RECIPIENT. 11 Violation/Termination of Agreement This Agreement shall expire automatically three (3) years after its signature by both parties. This Agreement will terminate immediately upon any material breach of a provision of this Agreement. The RECIPIENT accepts that the changing ethical framework of human genetic research may lead to: (i) alteration to the provisions of this Agreement, in which case the RECIPIENT may accept such alterations or terminate this Agreement; or (ii) the withdrawal of this Agreement in extreme circumstances. Either party shall have the right to terminate this Agreement with immediate effect upon giving written notice of termination to the other party. In the event that this Agreement is expired the RECIPIENT is required to destroy/discard any Data held, including but not limited to copies and backup copies. This shall not apply to the extent that DATA is saved in automatic back-up systems for which destruction shall follow the regular process of such back-up system, however, such DATA shall be eliminated within a period of four (4) weeks after the date of termination. Upon request of PROVIDER, the RECIPIENT will certify the destruction of the DATA. Sections 4, 5, 9 and 10 of this Agreement remain in full force and effect in case of termination. Notwithstanding the aforementioned, any provision of this Agreement related to confidentiality and/or DATA protection shall survive the expiration of this Agreement to the extent applicable statutory law provides for a deviating period of validity and effectiveness. Nothing contained in this paragraph shall restrict the right of the PROVIDER to seek injunctive relief to prevent any breach or threatened breach of this agreement, furthermore nothing contained in this paragraph shall prohibit the PROVIDER from pursuing any other remedies available to it for such breach or threatened breach, including the recovery of damages from RECIPIENT.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000441 Whole Genome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF50000151462 fastq.gz 5.5 GB
EGAF50000151463 fastq.gz 5.6 GB
EGAF50000151464 fastq.gz 5.1 GB
EGAF50000151465 fastq.gz 5.2 GB
EGAF50000151466 fastq.gz 4.4 GB
EGAF50000151467 fastq.gz 4.5 GB
EGAF50000151468 fastq.gz 5.2 GB
EGAF50000151469 fastq.gz 5.3 GB
EGAF50000151470 fastq.gz 5.8 GB
EGAF50000151471 fastq.gz 5.9 GB
EGAF50000151472 fastq.gz 4.9 GB
EGAF50000151473 fastq.gz 5.0 GB
EGAF50000151474 fastq.gz 5.6 GB
EGAF50000151475 fastq.gz 5.8 GB
EGAF50000151476 fastq.gz 6.2 GB
EGAF50000151477 fastq.gz 6.3 GB
EGAF50000151478 fastq.gz 5.9 GB
EGAF50000151479 fastq.gz 6.0 GB
EGAF50000151480 fastq.gz 4.0 GB
EGAF50000151481 fastq.gz 4.1 GB
EGAF50000151482 fastq.gz 3.7 GB
EGAF50000151483 fastq.gz 3.8 GB
EGAF50000151484 fastq.gz 3.6 GB
EGAF50000151485 fastq.gz 3.7 GB
EGAF50000151486 fastq.gz 4.3 GB
EGAF50000151487 fastq.gz 4.4 GB
EGAF50000151488 fastq.gz 4.3 GB
EGAF50000151489 fastq.gz 4.4 GB
EGAF50000151490 fastq.gz 5.2 GB
EGAF50000151491 fastq.gz 5.3 GB
EGAF50000151492 fastq.gz 4.3 GB
EGAF50000151493 fastq.gz 4.4 GB
EGAF50000151494 fastq.gz 3.8 GB
EGAF50000151495 fastq.gz 3.9 GB
EGAF50000151496 fastq.gz 3.8 GB
EGAF50000151497 fastq.gz 3.8 GB
EGAF50000151498 fastq.gz 3.7 GB
EGAF50000151499 fastq.gz 3.8 GB
EGAF50000151500 fastq.gz 4.0 GB
EGAF50000151501 fastq.gz 4.1 GB
EGAF50000151502 fastq.gz 4.8 GB
EGAF50000151503 fastq.gz 4.9 GB
EGAF50000151504 fastq.gz 3.4 GB
EGAF50000151505 fastq.gz 3.5 GB
EGAF50000151506 fastq.gz 3.9 GB
EGAF50000151507 fastq.gz 4.0 GB
EGAF50000151508 fastq.gz 4.7 GB
EGAF50000151509 fastq.gz 4.9 GB
EGAF50000151510 fastq.gz 4.4 GB
EGAF50000151511 fastq.gz 4.5 GB
EGAF50000151512 fastq.gz 4.0 GB
EGAF50000151513 fastq.gz 4.1 GB
EGAF50000151514 fastq.gz 4.2 GB
EGAF50000151515 fastq.gz 4.3 GB
EGAF50000151516 fastq.gz 4.7 GB
EGAF50000151517 fastq.gz 4.9 GB
EGAF50000151518 fastq.gz 4.3 GB
EGAF50000151519 fastq.gz 4.4 GB
EGAF50000151520 fastq.gz 4.3 GB
EGAF50000151521 fastq.gz 4.4 GB
EGAF50000151522 fastq.gz 4.6 GB
EGAF50000151523 fastq.gz 4.7 GB
EGAF50000151524 fastq.gz 4.0 GB
EGAF50000151525 fastq.gz 4.1 GB
EGAF50000151526 fastq.gz 4.5 GB
EGAF50000151527 fastq.gz 4.6 GB
EGAF50000151528 fastq.gz 5.0 GB
EGAF50000151529 fastq.gz 5.1 GB
EGAF50000151530 fastq.gz 4.2 GB
EGAF50000151531 fastq.gz 4.3 GB
EGAF50000151532 fastq.gz 3.7 GB
EGAF50000151533 fastq.gz 3.8 GB
EGAF50000151534 fastq.gz 4.4 GB
EGAF50000151535 fastq.gz 4.5 GB
EGAF50000151536 fastq.gz 4.0 GB
EGAF50000151537 fastq.gz 4.1 GB
EGAF50000151538 fastq.gz 4.6 GB
EGAF50000151539 fastq.gz 4.8 GB
EGAF50000151540 fastq.gz 3.8 GB
EGAF50000151541 fastq.gz 3.9 GB
EGAF50000151542 fastq.gz 3.7 GB
EGAF50000151543 fastq.gz 3.8 GB
EGAF50000151544 fastq.gz 3.8 GB
EGAF50000151545 fastq.gz 3.9 GB
EGAF50000151546 fastq.gz 3.9 GB
EGAF50000151547 fastq.gz 4.0 GB
EGAF50000151548 fastq.gz 4.5 GB
EGAF50000151549 fastq.gz 4.6 GB
EGAF50000151550 fastq.gz 3.9 GB
EGAF50000151551 fastq.gz 4.0 GB
EGAF50000151552 fastq.gz 5.4 GB
EGAF50000151553 fastq.gz 5.4 GB
EGAF50000151554 fastq.gz 4.2 GB
EGAF50000151555 fastq.gz 4.3 GB
EGAF50000151556 fastq.gz 3.8 GB
EGAF50000151557 fastq.gz 3.9 GB
EGAF50000151558 fastq.gz 4.1 GB
EGAF50000151559 fastq.gz 4.2 GB
EGAF50000151560 fastq.gz 4.1 GB
EGAF50000151561 fastq.gz 4.3 GB
EGAF50000151562 fastq.gz 3.8 GB
EGAF50000151563 fastq.gz 3.9 GB
EGAF50000151564 fastq.gz 3.7 GB
EGAF50000151565 fastq.gz 3.8 GB
EGAF50000151566 fastq.gz 6.1 GB
EGAF50000151567 fastq.gz 6.2 GB
EGAF50000151568 fastq.gz 4.1 GB
EGAF50000151569 fastq.gz 4.2 GB
EGAF50000151570 fastq.gz 1.2 GB
EGAF50000151571 fastq.gz 1.2 GB
EGAF50000151572 fastq.gz 5.1 GB
EGAF50000151573 fastq.gz 5.2 GB
EGAF50000151574 fastq.gz 4.5 GB
EGAF50000151575 fastq.gz 4.6 GB
EGAF50000151576 fastq.gz 3.7 GB
EGAF50000151577 fastq.gz 3.8 GB
EGAF50000151578 fastq.gz 5.4 GB
EGAF50000151579 fastq.gz 5.5 GB
EGAF50000151580 fastq.gz 3.9 GB
EGAF50000151581 fastq.gz 4.0 GB
EGAF50000151582 fastq.gz 2.8 GB
EGAF50000151583 fastq.gz 2.8 GB
EGAF50000151584 fastq.gz 4.4 GB
EGAF50000151585 fastq.gz 4.5 GB
EGAF50000151586 fastq.gz 3.7 GB
EGAF50000151587 fastq.gz 3.8 GB
EGAF50000151588 fastq.gz 3.9 GB
EGAF50000151589 fastq.gz 3.9 GB
EGAF50000151590 fastq.gz 4.8 GB
EGAF50000151591 fastq.gz 5.0 GB
EGAF50000151592 fastq.gz 4.2 GB
EGAF50000151593 fastq.gz 4.3 GB
EGAF50000151594 fastq.gz 4.1 GB
EGAF50000151595 fastq.gz 4.2 GB
EGAF50000151596 fastq.gz 4.0 GB
EGAF50000151597 fastq.gz 4.1 GB
EGAF50000151598 fastq.gz 4.3 GB
EGAF50000151599 fastq.gz 4.4 GB
EGAF50000151600 fastq.gz 4.6 GB
EGAF50000151601 fastq.gz 4.8 GB
EGAF50000151602 fastq.gz 4.4 GB
EGAF50000151603 fastq.gz 4.5 GB
EGAF50000151604 fastq.gz 4.6 GB
EGAF50000151605 fastq.gz 4.7 GB
EGAF50000151606 fastq.gz 3.6 GB
EGAF50000151607 fastq.gz 3.7 GB
EGAF50000151608 fastq.gz 5.2 GB
EGAF50000151609 fastq.gz 5.3 GB
EGAF50000151610 fastq.gz 7.4 GB
EGAF50000151611 fastq.gz 7.5 GB
EGAF50000151612 fastq.gz 4.9 GB
EGAF50000151613 fastq.gz 5.1 GB
EGAF50000151614 fastq.gz 4.3 GB
EGAF50000151615 fastq.gz 4.4 GB
EGAF50000151616 fastq.gz 3.6 GB
EGAF50000151617 fastq.gz 3.7 GB
EGAF50000151618 fastq.gz 5.7 GB
EGAF50000151619 fastq.gz 5.8 GB
EGAF50000151620 fastq.gz 5.0 GB
EGAF50000151621 fastq.gz 5.1 GB
EGAF50000151622 fastq.gz 5.1 GB
EGAF50000151623 fastq.gz 5.3 GB
EGAF50000151624 fastq.gz 5.4 GB
EGAF50000151625 fastq.gz 5.5 GB
EGAF50000151626 fastq.gz 5.5 GB
EGAF50000151627 fastq.gz 5.6 GB
EGAF50000151628 fastq.gz 4.3 GB
EGAF50000151629 fastq.gz 4.4 GB
EGAF50000151630 fastq.gz 4.2 GB
EGAF50000151631 fastq.gz 4.4 GB
EGAF50000151632 fastq.gz 3.9 GB
EGAF50000151633 fastq.gz 4.0 GB
EGAF50000151634 fastq.gz 4.0 GB
EGAF50000151635 fastq.gz 4.1 GB
EGAF50000151636 fastq.gz 3.6 GB
EGAF50000151637 fastq.gz 3.7 GB
EGAF50000151638 fastq.gz 3.8 GB
EGAF50000151639 fastq.gz 3.9 GB
EGAF50000151640 fastq.gz 3.9 GB
EGAF50000151641 fastq.gz 4.0 GB
EGAF50000151642 fastq.gz 3.7 GB
EGAF50000151643 fastq.gz 3.8 GB
EGAF50000151644 fastq.gz 3.9 GB
EGAF50000151645 fastq.gz 4.0 GB
EGAF50000151646 fastq.gz 4.7 GB
EGAF50000151647 fastq.gz 4.8 GB
EGAF50000151648 fastq.gz 4.6 GB
EGAF50000151649 fastq.gz 4.8 GB
EGAF50000151650 fastq.gz 4.1 GB
EGAF50000151651 fastq.gz 4.3 GB
EGAF50000151652 fastq.gz 4.0 GB
EGAF50000151653 fastq.gz 4.1 GB
EGAF50000151654 fastq.gz 4.1 GB
EGAF50000151655 fastq.gz 4.2 GB
EGAF50000151656 fastq.gz 4.0 GB
EGAF50000151657 fastq.gz 4.1 GB
EGAF50000151658 fastq.gz 4.1 GB
EGAF50000151659 fastq.gz 4.3 GB
EGAF50000151660 fastq.gz 3.9 GB
EGAF50000151661 fastq.gz 4.0 GB
EGAF50000151662 fastq.gz 6.4 GB
EGAF50000151663 fastq.gz 6.6 GB
EGAF50000151664 fastq.gz 4.5 GB
EGAF50000151665 fastq.gz 4.6 GB
EGAF50000151666 fastq.gz 4.2 GB
EGAF50000151667 fastq.gz 4.3 GB
EGAF50000151668 fastq.gz 4.0 GB
EGAF50000151669 fastq.gz 4.1 GB
EGAF50000151670 fastq.gz 3.1 GB
EGAF50000151671 fastq.gz 3.2 GB
EGAF50000151672 fastq.gz 3.7 GB
EGAF50000151673 fastq.gz 3.8 GB
EGAF50000151674 fastq.gz 5.7 GB
EGAF50000151675 fastq.gz 5.9 GB
EGAF50000151676 fastq.gz 8.9 GB
EGAF50000151677 fastq.gz 9.1 GB
EGAF50000151678 fastq.gz 4.1 GB
EGAF50000151679 fastq.gz 4.2 GB
EGAF50000151680 fastq.gz 4.7 GB
EGAF50000151681 fastq.gz 4.8 GB
EGAF50000151682 fastq.gz 4.4 GB
EGAF50000151683 fastq.gz 4.4 GB
EGAF50000151684 fastq.gz 3.0 GB
EGAF50000151685 fastq.gz 3.1 GB
EGAF50000151686 fastq.gz 4.5 GB
EGAF50000151687 fastq.gz 4.6 GB
EGAF50000151688 fastq.gz 4.2 GB
EGAF50000151689 fastq.gz 4.4 GB
EGAF50000151690 fastq.gz 3.9 GB
EGAF50000151691 fastq.gz 4.0 GB
EGAF50000151692 fastq.gz 5.0 GB
EGAF50000151693 fastq.gz 5.0 GB
EGAF50000151694 fastq.gz 4.0 GB
EGAF50000151695 fastq.gz 4.1 GB
EGAF50000151696 fastq.gz 3.8 GB
EGAF50000151697 fastq.gz 3.9 GB
236 Files (1.0 TB)