Transcriptome analysis of human iPSC-derived microglia in a novel human 3D cortical tissue model
scRNA-seq analysis of human iPSC-derived microglia in a novel, human in vitro 3D cortical tissue model. Samples include three distinct conditions (each as biological duplicates): wild-type microglia extracted from cultures after 1 month (WT_1mo) and 3 months (WT_3mo) of culturing, as well as knock-in microglia extracted from cultures carrying three familial AD mutations in the APP gene (Swedish, Iberian, Arctic; introduced by CRISPR/Cas9-mediated knock-in) after 3 months of culturing (KI_3mo).
- 23/02/2026
- 3 samples
- DAC: EGAC50000000303
- Technology: Illumina NovaSeq 6000
Policy for "Transcriptome analysis of human iPSC-derived microglia in a novel human 3D cortical tissue model"
Access to generated data is made available by completing the data access agreement for review by the data access committee and will be granted exclusively to qualified investigators for appropriate use.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000000469 | Transcriptome Sequencing |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
i
|
|---|---|---|---|---|
| EGAF50000158840 | csv | 356 Bytes |
|
|
| EGAF50000158841 | fastq.gz | 53.1 GB |
|
|
| EGAF50000158842 | fastq.gz | 48.8 GB |
|
|
| EGAF50000158843 | fastq.gz | 55.7 GB |
|
|
| EGAF50000158844 | fastq.gz | 51.0 GB |
|
|
| EGAF50000158845 | fastq.gz | 46.6 GB |
|
|
| EGAF50000158846 | fastq.gz | 42.6 GB |
|
|
| EGAF50000158847 | fastq.gz | 1.3 GB |
|
|
| EGAF50000158848 | fastq.gz | 1.2 GB |
|
|
| EGAF50000158849 | fastq.gz | 1.2 GB |
|
|
| EGAF50000158850 | fastq.gz | 1.2 GB |
|
|
| EGAF50000158851 | fastq.gz | 1.2 GB |
|
|
| EGAF50000158852 | fastq.gz | 1.1 GB |
|
|
| 13 Files (305.1 GB) | ||||
