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Disease recurrence after pathologic response

In this study we aim to gain insight into the mechanisms of immune evasion after initial pathologic response to neoadjuvant immune checkpoint inhibition in macroscopic stage III melanoma by pooling data of the neoadjuvant OpACIN, OpACIN-neo and PRADO trials. Therefore we analyzed in-depth paired baseline and recurrent tumor samples through a.o. DNA sequencing analyses.

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Netherlands Cancer Institute - Antoni van Leeuwenhoek (NKI-AVL) general policy

Data is available under reasonable request. All data requests will be reviewed by the NKI IRB and must be supported by the Principal Investigator of the study. The researcher will need to sign a data access agreement with the NKI after approval.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000488 Exome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF50000167920 fastq.gz 2.6 GB
EGAF50000167921 fastq.gz 2.4 GB
EGAF50000167922 fastq.gz 2.4 GB
EGAF50000167923 fastq.gz 2.2 GB
EGAF50000167924 fastq.gz 2.8 GB
EGAF50000167925 fastq.gz 2.6 GB
EGAF50000167926 fastq.gz 4.1 GB
EGAF50000167927 fastq.gz 3.9 GB
EGAF50000167928 fastq 56.1 MB
EGAF50000167929 fastq.gz 7.1 GB
EGAF50000167930 fastq.gz 5.8 GB
EGAF50000167931 fastq.gz 6.1 GB
EGAF50000167979 fastq.gz 6.5 GB
EGAF50000167980 fastq.gz 6.3 GB
EGAF50000167981 fastq.gz 8.5 GB
EGAF50000167982 fastq.gz 8.1 GB
EGAF50000167983 fastq.gz 4.9 GB
EGAF50000167984 fastq.gz 4.8 GB
EGAF50000167985 fastq.gz 2.8 GB
EGAF50000167986 fastq.gz 2.7 GB
EGAF50000167987 fastq.gz 2.9 GB
EGAF50000167988 fastq.gz 2.8 GB
EGAF50000167989 fastq.gz 3.2 GB
EGAF50000167990 fastq.gz 3.1 GB
EGAF50000167991 fastq.gz 3.5 GB
EGAF50000167992 fastq.gz 3.6 GB
EGAF50000167993 fastq.gz 3.3 GB
EGAF50000167994 fastq.gz 3.2 GB
EGAF50000167995 fastq.gz 3.7 GB
EGAF50000167996 fastq.gz 3.6 GB
EGAF50000167997 fastq.gz 4.0 GB
EGAF50000167998 fastq.gz 4.2 GB
EGAF50000167999 fastq.gz 3.2 GB
EGAF50000168000 fastq.gz 3.2 GB
EGAF50000168001 fastq.gz 3.1 GB
EGAF50000168002 fastq.gz 3.3 GB
EGAF50000168003 fastq.gz 6.2 GB
EGAF50000168004 fastq.gz 5.9 GB
38 Files (152.4 GB)