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Disease recurrence after pathologic response

In this study we aim to gain insight into the mechanisms of immune evasion after initial pathologic response to neoadjuvant immune checkpoint inhibition in macroscopic stage III melanoma by pooling data of the neoadjuvant OpACIN, OpACIN-neo and PRADO trials. Therefore we analyzed in-depth paired baseline(n=10) and recurrent tumor samples of the lymph nodes(n=10) and brain metastasis (n=2) through Whole Exome Sequencing (WES) analyses.

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Netherlands Cancer Institute - Antoni van Leeuwenhoek (NKI-AVL) general policy

Data is available under reasonable request. All data requests will be reviewed by the NKI IRB and must be supported by the Principal Investigator of the study. The researcher will need to sign a data access agreement with the NKI after approval.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000488 Exome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF50000093707 fastq.gz 3.6 GB Report
EGAF50000093708 fastq.gz 3.5 GB Report
EGAF50000093709 fastq.gz 2.2 GB Report
EGAF50000093710 fastq.gz 2.4 GB Report
EGAF50000093717 fastq.gz 3.5 GB Report
EGAF50000093718 fastq.gz 3.6 GB Report
EGAF50000093817 fastq.gz 4.2 GB Report
EGAF50000093818 fastq.gz 4.4 GB Report
EGAF50000093863 fastq.gz 5.9 GB Report
EGAF50000093864 fastq.gz 6.1 GB Report
EGAF50000093873 fastq.gz 4.0 GB Report
EGAF50000093874 fastq.gz 4.1 GB Report
EGAF50000093949 fastq.gz 2.5 GB Report
EGAF50000093950 fastq.gz 2.6 GB Report
EGAF50000093975 fastq.gz 3.2 GB Report
EGAF50000093976 fastq.gz 3.3 GB Report
EGAF50000093991 fastq.gz 2.4 GB Report
EGAF50000093992 fastq.gz 2.5 GB Report
EGAF50000167932 fastq.gz 2.1 GB Report
EGAF50000167933 fastq.gz 2.0 GB Report
EGAF50000167934 fastq.gz 3.5 GB Report
EGAF50000167935 fastq.gz 3.5 GB Report
EGAF50000167936 fastq.gz 1.8 GB Report
EGAF50000167937 fastq.gz 1.8 GB Report
EGAF50000167938 fastq.gz 7.9 GB Report
EGAF50000167939 fastq.gz 8.0 GB Report
EGAF50000167940 fastq.gz 4.2 GB Report
EGAF50000167941 fastq.gz 4.0 GB Report
EGAF50000167942 fastq.gz 3.9 GB Report
EGAF50000167943 fastq.gz 3.8 GB Report
EGAF50000167944 fastq.gz 4.5 GB Report
EGAF50000167945 fastq.gz 4.6 GB Report
EGAF50000167946 fastq.gz 3.2 GB Report
EGAF50000167947 fastq.gz 3.2 GB Report
EGAF50000167948 fastq.gz 3.5 GB Report
EGAF50000167949 fastq.gz 3.6 GB Report
EGAF50000167950 fastq.gz 3.9 GB Report
EGAF50000167951 fastq.gz 3.9 GB Report
EGAF50000167952 fastq.gz 4.0 GB Report
EGAF50000167953 fastq.gz 3.9 GB Report
EGAF50000167954 fastq.gz 4.6 GB Report
EGAF50000167955 fastq.gz 4.6 GB Report
EGAF50000167956 fastq.gz 3.3 GB Report
EGAF50000167957 fastq.gz 3.3 GB Report
EGAF50000167958 fastq.gz 2.8 GB Report
EGAF50000167959 fastq.gz 2.7 GB Report
EGAF50000167960 fastq.gz 7.8 GB Report
EGAF50000167961 fastq.gz 7.2 GB Report
EGAF50000167962 fastq.gz 3.6 GB Report
EGAF50000167963 fastq.gz 3.5 GB Report
EGAF50000167964 fastq.gz 4.0 GB Report
EGAF50000167965 fastq.gz 4.0 GB Report
EGAF50000167966 fastq.gz 3.5 GB Report
EGAF50000167967 fastq.gz 3.6 GB Report
EGAF50000167969 fastq.gz 11.0 GB Report
EGAF50000167970 fastq.gz 10.6 GB Report
EGAF50000167971 fastq.gz 6.1 GB Report
EGAF50000167972 fastq.gz 6.3 GB Report
EGAF50000167973 fastq.gz 2.8 GB Report
EGAF50000167974 fastq.gz 2.9 GB Report
EGAF50000167975 fastq.gz 3.9 GB Report
EGAF50000167976 fastq.gz 4.0 GB Report
EGAF50000167977 fastq.gz 3.1 GB Report
EGAF50000167978 fastq.gz 3.0 GB Report
64 Files (261.1 GB)