Sex Differences in MAGEL2 Gene Promoter Methylation in High Functioning Autism - Trends from a Pilot Study Using Nanopore Cas9 Targeted Long Read Sequencing
Using DNA extracted from peripheral blood, Cas9-targeted nanopore DNA sequencing was used to analyze MAGEL2 gene, including its entire regulatory construct (chr15:23639316-23651466), for sequence variation and 5-methyl-cytosine (5mC) modification in a cohort of adults with HFA compared to sex- and age-matched NC.
- 30/08/2024
- 40 samples
- DAC: EGAC50000000349
- Technology: PromethION
- HMB DUO:0000006 (version: 2021-02-23)health or medical or biomedical researchThis data use permission indicates that use is allowed for health/medical/biomedical purposes; does not include the study of population origins or ancestry.
- NMDS DUO:0000015 (version: 2021-02-23)no general methods researchThis data use modifier indicates that use does not allow methods development research (e.g., development of software or algorithms).
- NPUNCU DUO:0000018 (version: 2021-02-23)not for profit, non commercial use onlyThis data use modifier indicates that use of the data is limited to not-for-profit organizations and not-for-profit use, non-commercial use.
- IRB DUO:0000021 (version: 2021-02-23)ethics approval requiredThis data use modifier indicates that the requestor must provide documentation of local IRB/ERB approval.
- GS DUO:0000022 (version: 2021-02-23)geographical restrictionThis data use modifier indicates that use is limited to within a specific geographic region.
Policy nCATS
https://ega-archive.org/access/data-access-committee/policy-documentation/
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000000508 | Epigenetics |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF50000171862 | bai | 1.6 MB | ||
| EGAF50000171863 | bam | 38.0 MB | ||
| EGAF50000171864 | bai | 1.7 MB | ||
| EGAF50000171865 | bam | 135.7 MB | ||
| EGAF50000171866 | bai | 1.7 MB | ||
| EGAF50000171867 | bam | 164.4 MB | ||
| EGAF50000171868 | bai | 1.6 MB | ||
| EGAF50000171869 | bam | 51.2 MB | ||
| EGAF50000171870 | bai | 1.7 MB | ||
| EGAF50000171871 | bam | 61.8 MB | ||
| EGAF50000171872 | bai | 1.6 MB | ||
| EGAF50000171873 | bam | 85.9 MB | ||
| EGAF50000171874 | bai | 1.6 MB | ||
| EGAF50000171875 | bam | 180.1 MB | ||
| EGAF50000171876 | bai | 1.7 MB | ||
| EGAF50000171877 | bam | 34.7 MB | ||
| EGAF50000171878 | bai | 1.6 MB | ||
| EGAF50000171879 | bam | 112.8 MB | ||
| EGAF50000171880 | bai | 1.8 MB | ||
| EGAF50000171881 | bam | 50.3 MB | ||
| EGAF50000171882 | bai | 1.6 MB | ||
| EGAF50000171883 | bam | 199.9 MB | ||
| EGAF50000171884 | bai | 1.8 MB | ||
| EGAF50000171885 | bam | 153.4 MB | ||
| EGAF50000171886 | bai | 1.8 MB | ||
| EGAF50000171887 | bam | 106.3 MB | ||
| EGAF50000171888 | bai | 1.7 MB | ||
| EGAF50000171889 | bam | 62.5 MB | ||
| EGAF50000171890 | bai | 1.6 MB | ||
| EGAF50000171891 | bam | 165.8 MB | ||
| EGAF50000171892 | bai | 1.7 MB | ||
| EGAF50000171893 | bam | 58.7 MB | ||
| EGAF50000171894 | bai | 1.6 MB | ||
| EGAF50000171895 | bam | 198.0 MB | ||
| EGAF50000171896 | bai | 1.7 MB | ||
| EGAF50000171897 | bam | 80.3 MB | ||
| EGAF50000171898 | bai | 1.6 MB | ||
| EGAF50000171899 | bam | 61.0 MB | ||
| EGAF50000171900 | bai | 1.7 MB | ||
| EGAF50000171901 | bam | 72.6 MB | ||
| EGAF50000171902 | bai | 1.6 MB | ||
| EGAF50000171903 | bam | 226.0 MB | ||
| EGAF50000171904 | bai | 1.8 MB | ||
| EGAF50000171905 | bam | 47.6 MB | ||
| EGAF50000171906 | bai | 1.6 MB | ||
| EGAF50000171907 | bam | 266.1 MB | ||
| EGAF50000171908 | bai | 1.6 MB | ||
| EGAF50000171909 | bam | 70.6 MB | ||
| EGAF50000171910 | bai | 1.7 MB | ||
| EGAF50000171911 | bam | 53.5 MB | ||
| EGAF50000171912 | bai | 1.6 MB | ||
| EGAF50000171913 | bam | 152.3 MB | ||
| EGAF50000171914 | bai | 1.8 MB | ||
| EGAF50000171915 | bam | 46.3 MB | ||
| EGAF50000171916 | bai | 1.6 MB | ||
| EGAF50000171917 | bam | 191.3 MB | ||
| EGAF50000171918 | bai | 1.8 MB | ||
| EGAF50000171919 | bam | 285.9 MB | ||
| EGAF50000171920 | bai | 1.7 MB | ||
| EGAF50000171921 | bam | 143.4 MB | ||
| EGAF50000171922 | bai | 1.7 MB | ||
| EGAF50000171923 | bam | 47.0 MB | ||
| EGAF50000171924 | bai | 1.6 MB | ||
| EGAF50000171925 | bam | 160.7 MB | ||
| EGAF50000171926 | bai | 1.7 MB | ||
| EGAF50000171927 | bam | 142.9 MB | ||
| EGAF50000171928 | bai | 1.8 MB | ||
| EGAF50000171929 | bam | 149.8 MB | ||
| EGAF50000171930 | bai | 1.7 MB | ||
| EGAF50000171931 | bam | 284.4 MB | ||
| EGAF50000171932 | bai | 1.7 MB | ||
| EGAF50000171933 | bam | 33.3 MB | ||
| EGAF50000171934 | bai | 1.6 MB | ||
| EGAF50000171935 | bam | 24.6 MB | ||
| EGAF50000171936 | bai | 1.6 MB | ||
| EGAF50000171937 | bam | 93.8 MB | ||
| EGAF50000171938 | bai | 1.6 MB | ||
| EGAF50000171939 | bam | 216.8 MB | ||
| EGAF50000171940 | bai | 1.6 MB | ||
| EGAF50000171941 | bam | 88.8 MB | ||
| EGAF50000171942 | tsv | 31.6 MB | ||
| EGAF50000171943 | tsv | 108.9 MB | ||
| EGAF50000171944 | tsv | 133.4 MB | ||
| EGAF50000171945 | tsv | 41.0 MB | ||
| EGAF50000171946 | tsv | 48.9 MB | ||
| EGAF50000171947 | tsv | 140.7 MB | ||
| EGAF50000171948 | tsv | 65.9 MB | ||
| EGAF50000171949 | tsv | 28.3 MB | ||
| EGAF50000171950 | tsv | 87.2 MB | ||
| EGAF50000171951 | tsv | 40.8 MB | ||
| EGAF50000171952 | tsv | 114.3 MB | ||
| EGAF50000171953 | tsv | 149.7 MB | ||
| EGAF50000171954 | tsv | 119.5 MB | ||
| EGAF50000171955 | tsv | 81.1 MB | ||
| EGAF50000171956 | tsv | 48.0 MB | ||
| EGAF50000171957 | tsv | 44.4 MB | ||
| EGAF50000171958 | tsv | 60.3 MB | ||
| EGAF50000171959 | tsv | 47.1 MB | ||
| EGAF50000171960 | tsv | 148.8 MB | ||
| EGAF50000171961 | tsv | 58.8 MB | ||
| EGAF50000171962 | tsv | 167.8 MB | ||
| EGAF50000171963 | tsv | 37.5 MB | ||
| EGAF50000171964 | tsv | 53.8 MB | ||
| EGAF50000171965 | tsv | 111.6 MB | ||
| EGAF50000171966 | tsv | 214.3 MB | ||
| EGAF50000171967 | tsv | 42.9 MB | ||
| EGAF50000171968 | tsv | 34.5 MB | ||
| EGAF50000171969 | tsv | 138.6 MB | ||
| EGAF50000171970 | tsv | 220.0 MB | ||
| EGAF50000171971 | tsv | 110.0 MB | ||
| EGAF50000171972 | tsv | 38.1 MB | ||
| EGAF50000171973 | tsv | 125.8 MB | ||
| EGAF50000171974 | tsv | 104.7 MB | ||
| EGAF50000171975 | tsv | 217.0 MB | ||
| EGAF50000171976 | tsv | 113.6 MB | ||
| EGAF50000171977 | tsv | 26.6 MB | ||
| EGAF50000171978 | tsv | 19.9 MB | ||
| EGAF50000171979 | tsv | 163.6 MB | ||
| EGAF50000171980 | tsv | 68.4 MB | ||
| EGAF50000171981 | vcf | 3.2 kB | ||
| EGAF50000171982 | vcf | 5.6 kB | ||
| EGAF50000171983 | vcf | 3.6 kB | ||
| EGAF50000171984 | vcf | 5.3 kB | ||
| EGAF50000171985 | vcf | 5.4 kB | ||
| EGAF50000171986 | vcf | 2.9 kB | ||
| EGAF50000171987 | vcf | 5.6 kB | ||
| EGAF50000171988 | vcf | 5.4 kB | ||
| EGAF50000171989 | vcf | 4.6 kB | ||
| EGAF50000171990 | vcf | 5.4 kB | ||
| EGAF50000171991 | vcf | 5.4 kB | ||
| EGAF50000171992 | vcf | 5.2 kB | ||
| EGAF50000171993 | vcf | 4.7 kB | ||
| EGAF50000171994 | vcf | 5.4 kB | ||
| EGAF50000171995 | vcf | 7.2 kB | ||
| EGAF50000171996 | vcf | 5.8 kB | ||
| EGAF50000171997 | vcf | 5.9 kB | ||
| EGAF50000171998 | vcf | 5.1 kB | ||
| EGAF50000171999 | vcf | 6.5 kB | ||
| EGAF50000172000 | vcf | 5.4 kB | ||
| EGAF50000172001 | vcf | 5.4 kB | ||
| EGAF50000172002 | vcf | 3.7 kB | ||
| EGAF50000172003 | vcf | 6.0 kB | ||
| EGAF50000172004 | vcf | 5.6 kB | ||
| EGAF50000172005 | vcf | 5.8 kB | ||
| EGAF50000172006 | vcf | 5.5 kB | ||
| EGAF50000172007 | vcf | 5.6 kB | ||
| EGAF50000172008 | vcf | 4.1 kB | ||
| EGAF50000172009 | vcf | 5.8 kB | ||
| EGAF50000172010 | tsv | 73.2 MB | ||
| EGAF50000172011 | vcf | 5.7 kB | ||
| EGAF50000172012 | vcf | 5.1 kB | ||
| EGAF50000172013 | vcf | 5.1 kB | ||
| EGAF50000172014 | vcf | 2.7 kB | ||
| EGAF50000172015 | vcf | 2.7 kB | ||
| EGAF50000172016 | vcf | 5.4 kB | ||
| EGAF50000172017 | vcf | 6.0 kB | ||
| EGAF50000172018 | vcf | 6.0 kB | ||
| EGAF50000172019 | vcf | 3.6 kB | ||
| EGAF50000172020 | vcf | 4.9 kB | ||
| EGAF50000172021 | vcf | 3.1 kB | ||
| 160 Files (8.5 GB) | ||||