About file location

As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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RNAseq data of brain metastasis samples

Paired-end RNA sequencing data from 95 brain metastasis samples with different primary origins. Sequencing was performed on the Illumina HiSeq 3000.

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DAC for "Identification and characterization of tertiary lymphoid structures in brain metastases"

Data Transfer Agreement of Human Genomic Data for Research Purposes Between: (1) Deutsches Krebsforschungszentrum (DKFZ), Stiftung des öffentlichen Rechts, legally represented by its Management Board , Prof. Dr. med. Michael Baumann and Ursula Weyrich Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany (“PROVIDER“) and (2) [INSERT INSTITUTION DETAILS] (“RECIPIENT”). 1 Preamble Public genetic sequence databases are a critical part of our academic biomedical research infrastructure. However, human genetic data should only be made public if we can adequately protect the privacy of research subjects. Individual genomic sequence data are sensitive patient data and any attempt to re-identify such data is forbidden under any circumstances. Our efforts to understand disease susceptibility or therapeutic opportunity require access to large genomic data sets. Therefore, the special privacy challenges posed by genomic data are addressed by PROVIDER with this Agreement. In response to the RECIPIENT's request for access to the DATA (as defined below), PROVIDER and the RECIPIENT agree as follows: 2 Definitions “DATA” shall mean all and any human genetic data obtained by the RECIPIENT from the PROVIDER including the Data Subjects’ e.g. age, sex and tumor pathology (as listed in Annex 2). For the avoidance of doubt, Data does not include samples or biological materials; “DATA SUBJECT” shall mean the person (irrespective of the state of health) to whom Data refers and who has been informed of the purpose for which the Data is held and has given his/her informed consent thereto; “COMMERCIAL PURPOSES” shall mean the sale, lease, license, or other transfer and/or the use of the DATA to and/or by a for-profit organization. However, industrially sponsored academic research shall not be considered a use of the DATA for Commercial Purposes per se. “INTELLECTUAL PROPERTY” shall mean (i) patents, designs, trademarks and trade names (whether registered or unregistered), copyright and related rights, database rights, know-how and confidential information; (ii) all other intellectual property rights and similar or equivalent rights (whether registered or unregistered and whether registrable or unregistrable) anywhere in the world which currently exist or are recognized in the future; and (iii) applications, extensions and renewals in relation to any such rights; “RECIPIENT SCIENTIST” shall mean a researcher (or an individual conducting Research under the supervision of a researcher) that is employed by the RECIPIENT and is bound by confidentiality and non-use obligations in respect of DATA and who has accepted the terms of this Agreement in writing (however, for the avoidance of doubt, without being a party to this Agreement) and has received acknowledgement of its acceptance. For the avoidance of doubt and without having explicitly accepted the terms of this Agreement in writing, “RECIPIENT SCIENTIST” may also include any other RECIPIENT’s employees, students, visiting academics, contractors, sub-contractors or independent consultants provided that any of such latter individuals is bound by confidentiality and non- use obligations no less onerous than those binding the RECIPIENT’s employees; “RESEARCH” shall mean research that is seeking to advance the understanding and treatment of cancer and closely related diseases, and work on statistical methods that may be applied to such research; “PROJECT” shall mean a detailed description as in Annex 3; 3 Purpose of the Project The RECIPIENT agrees to use DATA only for RESEARCH as described in the purpose of the PROJECT (Annex 3). 4 Confidentiality The RECIPIENT agrees to preserve, at all times, the confidentiality of DATA pertaining to DATA SUBJECTs. In particular, the RECIPIENT undertakes not to use, or attempt to use the DATA to deliberately compromise or otherwise infringe the confidentiality of information on DATA SUBJECTs and their respective rights to privacy. 5 DATA Protection The Recipient and its RECIPIENT SCIENTIST are covered by and the RECIPIENT shall, and shall procure that its RECIPIENT SCIENTISTS shall, comply with the obligations contained in the applicable German and EU data protection laws and regulations as amended from time to time. In particular, the RECIPIENT and its RECIPIENT SCIENTISTs inter alia understands, and shall procure that its RECIPIENT SCIENTISTs understand, their duties under the German and EU legislation in relation to the handling of DATA and the rights of DATA SUBJECTs. The RECIPIENT agrees that it, and its RECIPIENT SCIENTISTs, shall not analyze or make any use of the DATA in such a way that has the potential to: a) lead to the re-identification of any DATA SUBJECT; or b) compromise the anonymity of any DATA SUBJECT in any way. The RECIPIENT shall, and it shall procure that its RECIPIENT SCIENTISTS shall, adhere to the principles of IT-Security as set forth in Annex 1 hereto. 6 Access and Governance The RECIPIENT agrees that it shall take all (commercially) reasonable security precautions to keep the DATA confidential, such precautions to be no less onerous than in the applicable German and EU data protection laws and regulations. The RECIPIENT agrees to use the DATA solely for RESEARCH in the frame of the purpose of the PROJECT. The RECIPIENT agrees that the DATA shall not be distributed or released to any other location and/or to any other person other than RECIPIENT SCIENTISTs or laboratory personnel under the RECIPIENT SCIENTISTs direct supervision. RECIPIENT does not have the right to sublicense the DATA. RECIPIENT shall inform PROVIDER about any third party requests for the DATA. PROVIDER reserves the right to request and inspect DATA security and management documentation at the RECIPIENT’s premises to ensure the adequacy of DATA protection measures with prior notice during the RECIPIENT’s ordinary working hours. DATA shall not be used for COMMERCIAL PURPOSES (e.g. diagnostic services). In case of intended commercial use of DATA, the RECIPIENT shall start negotiations in good faith leading to a fair market compensation of PROVIDER. Such a disclosure of DATA shall require a binding declaration of consent in writing from the person concerned. 7 Errors The RECIPIENT agrees to notify the PROVIDER of any errors detected in the DATA without undue delay. 8 DATA reissue The RECIPIENT accepts that PROVIDER will reissue DATA from time to time, with suitable versioning. If DATA is reissued at the request of the DATA SUBJECT and/or as the result of other ethical scrutiny, the RECIPIENT agrees to destroy all earlier versions of the DATA without undue delay once he has received such information. This shall not apply to the extent that DATA is saved in automatic back-up systems for which destruction shall follow the regular process of such back-up system, however, such DATA shall be eliminated within a period of four (4) weeks after reception of the respective request to do so or within a period of four (4) weeks upon termination in accordance with this Agreement. 9 INTELLECTUAL PROPERTY The RECIPIENT recognizes that nothing in this Agreement shall operate to transfer to the RECIPIENT or its RECIPIENT SCIENTISTs any INTELLECTUAL PROPERTY rights in or relating to the DATA, i.e. ownership of DATA remains unchanged. The RECIPIENT does not have the right to sublicense the DATA. The RECIPIENT shall inform PROVIDER about any third party requests for the DATA. In case the RECIPIENT and its RECIPIENT SCIENTISTs develops INTELLECTUAL PROPERTY based on or related to DATA as set forth in this Agreement the RECIPIENT shall become owner of such results. The RECIPIENT will inform PROVIDER about all developed INTELLECTUAL PROPERTY based on or related to DATA as set forth in this Agreement without undue delay in writing. The RECIPIENT grants PROVIDER a non-exclusive, non-transferable, royalty-free, perpetual, non-sublicensable right to use such developed INTELLECTUAL PROPERTY for internal research purposes including collaborations with any third parties excluding any COMMERCIAL PURPOSES. 10 Publications The RECIPIENT agrees to acknowledge in any RECIPIENT’s work based in whole or part on the DATA, any PROVIDER publications which encompass and from which DATA derive, the respective version of the DATA obtained, and the role of PROVIDER. The RECIPIENT is also entitled to release publications and, in doing so, agrees to acknowledge any of PROVIDER’s work based in whole or part on the DATA in its publication. The RECIPIENT will also declare in any such work that PROVIDER and its employees bear no responsibility for the further analysis or interpretation of the DATA by the RECIPIENT. 11 Violation/Termination of Agreement This Agreement shall expire automatically three (3) years after its signature by both parties. This Agreement will terminate immediately upon any material breach of a provision of this Agreement. The RECIPIENT accepts that the changing ethical framework of human genetic research may lead to: (i) alteration to the provisions of this Agreement, in which case the RECIPIENT may accept such alterations or terminate this Agreement; or (ii) the withdrawal of this Agreement in extreme circumstances. Either party shall have the right to terminate this Agreement with immediate effect upon giving written notice of termination to the other party. In the event that this Agreement is expired the RECIPIENT is required to destroy/discard any Data held, including but not limited to copies and backup copies. This shall not apply to the extent that DATA is saved in automatic back-up systems for which destruction shall follow the regular process of such back-up system, however, such DATA shall be eliminated within a period of four (4) weeks after the date of termination. Upon request of PROVIDER, the RECIPIENT will certify the destruction of the DATA. Sections 4, 5, 9 and 10 of this Agreement remain in full force and effect in case of termination. Notwithstanding the aforementioned, any provision of this Agreement related to confidentiality and/or DATA protection shall survive the expiration of this Agreement to the extent applicable statutory law provides for a deviating period of validity and effectiveness. Nothing contained in this paragraph shall restrict the right of the PROVIDER to seek injunctive relief to prevent any breach or threatened breach of this agreement, furthermore nothing contained in this paragraph shall prohibit the PROVIDER from pursuing any other remedies available to it for such breach or threatened breach, including the recovery of damages from RECIPIENT.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000563 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF50000187973 fastq.gz 1.4 GB
EGAF50000187974 fastq.gz 1.5 GB
EGAF50000187975 fastq.gz 2.6 GB
EGAF50000187976 fastq.gz 2.9 GB
EGAF50000187977 fastq.gz 2.4 GB
EGAF50000187978 fastq.gz 2.7 GB
EGAF50000187979 fastq.gz 3.2 GB
EGAF50000187980 fastq.gz 3.8 GB
EGAF50000187981 fastq.gz 2.0 GB
EGAF50000187982 fastq.gz 2.2 GB
EGAF50000187983 fastq.gz 2.4 GB
EGAF50000187984 fastq.gz 2.7 GB
EGAF50000187985 fastq.gz 2.8 GB
EGAF50000187986 fastq.gz 3.2 GB
EGAF50000187987 fastq.gz 2.8 GB
EGAF50000187988 fastq.gz 3.0 GB
EGAF50000187989 fastq.gz 2.8 GB
EGAF50000187990 fastq.gz 3.0 GB
EGAF50000187991 fastq.gz 2.2 GB
EGAF50000187992 fastq.gz 2.2 GB
EGAF50000187993 fastq.gz 2.1 GB
EGAF50000187994 fastq.gz 2.3 GB
EGAF50000187995 fastq.gz 2.4 GB
EGAF50000187996 fastq.gz 2.6 GB
EGAF50000187997 fastq.gz 2.6 GB
EGAF50000187998 fastq.gz 2.9 GB
EGAF50000187999 fastq.gz 3.1 GB
EGAF50000188000 fastq.gz 3.5 GB
EGAF50000188001 fastq.gz 2.2 GB
EGAF50000188002 fastq.gz 2.3 GB
EGAF50000188003 fastq.gz 2.0 GB
EGAF50000188004 fastq.gz 2.3 GB
EGAF50000188005 fastq.gz 2.5 GB
EGAF50000188006 fastq.gz 2.7 GB
EGAF50000188007 fastq.gz 2.5 GB
EGAF50000188008 fastq.gz 2.8 GB
EGAF50000188009 fastq.gz 2.5 GB
EGAF50000188010 fastq.gz 2.9 GB
EGAF50000188011 fastq.gz 2.4 GB
EGAF50000188012 fastq.gz 2.7 GB
EGAF50000188013 fastq.gz 2.5 GB
EGAF50000188014 fastq.gz 2.8 GB
EGAF50000188015 fastq.gz 2.6 GB
EGAF50000188016 fastq.gz 3.0 GB
EGAF50000188017 fastq.gz 2.4 GB
EGAF50000188018 fastq.gz 2.8 GB
EGAF50000188019 fastq.gz 2.3 GB
EGAF50000188020 fastq.gz 2.6 GB
EGAF50000188021 fastq.gz 2.3 GB
EGAF50000188022 fastq.gz 2.6 GB
EGAF50000188023 fastq.gz 3.5 GB
EGAF50000188024 fastq.gz 4.0 GB
EGAF50000188025 fastq.gz 2.5 GB
EGAF50000188026 fastq.gz 2.7 GB
EGAF50000188027 fastq.gz 2.8 GB
EGAF50000188028 fastq.gz 3.1 GB
EGAF50000188029 fastq.gz 2.4 GB
EGAF50000188030 fastq.gz 2.7 GB
EGAF50000188031 fastq.gz 2.7 GB
EGAF50000188032 fastq.gz 3.0 GB
EGAF50000188033 fastq.gz 2.8 GB
EGAF50000188034 fastq.gz 3.0 GB
EGAF50000188035 fastq.gz 2.2 GB
EGAF50000188036 fastq.gz 2.5 GB
EGAF50000188037 fastq.gz 3.3 GB
EGAF50000188038 fastq.gz 3.7 GB
EGAF50000188039 fastq.gz 2.7 GB
EGAF50000188040 fastq.gz 2.9 GB
EGAF50000188041 fastq.gz 2.3 GB
EGAF50000188042 fastq.gz 2.6 GB
EGAF50000188043 fastq.gz 2.2 GB
EGAF50000188044 fastq.gz 2.5 GB
EGAF50000188045 fastq.gz 3.5 GB
EGAF50000188046 fastq.gz 4.0 GB
EGAF50000188047 fastq.gz 2.7 GB
EGAF50000188048 fastq.gz 3.0 GB
EGAF50000188049 fastq.gz 3.7 GB
EGAF50000188050 fastq.gz 4.1 GB
EGAF50000188051 fastq.gz 3.6 GB
EGAF50000188052 fastq.gz 4.1 GB
EGAF50000188053 fastq.gz 2.5 GB
EGAF50000188054 fastq.gz 2.7 GB
EGAF50000188055 fastq.gz 2.3 GB
EGAF50000188056 fastq.gz 2.6 GB
EGAF50000188057 fastq.gz 3.2 GB
EGAF50000188058 fastq.gz 3.4 GB
EGAF50000188059 fastq.gz 2.2 GB
EGAF50000188060 fastq.gz 2.5 GB
EGAF50000188061 fastq.gz 2.7 GB
EGAF50000188062 fastq.gz 3.1 GB
EGAF50000188063 fastq.gz 2.5 GB
EGAF50000188064 fastq.gz 2.8 GB
EGAF50000188065 fastq.gz 2.2 GB
EGAF50000188066 fastq.gz 2.3 GB
EGAF50000188067 fastq.gz 2.1 GB
EGAF50000188068 fastq.gz 2.4 GB
EGAF50000188069 fastq.gz 2.3 GB
EGAF50000188070 fastq.gz 2.4 GB
EGAF50000188071 fastq.gz 3.2 GB
EGAF50000188072 fastq.gz 3.6 GB
EGAF50000188073 fastq.gz 2.4 GB
EGAF50000188074 fastq.gz 2.7 GB
EGAF50000188075 fastq.gz 2.4 GB
EGAF50000188076 fastq.gz 2.7 GB
EGAF50000188077 fastq.gz 2.0 GB
EGAF50000188078 fastq.gz 2.2 GB
EGAF50000188079 fastq.gz 3.8 GB
EGAF50000188080 fastq.gz 4.1 GB
EGAF50000188081 fastq.gz 2.5 GB
EGAF50000188082 fastq.gz 2.7 GB
EGAF50000188083 fastq.gz 2.3 GB
EGAF50000188084 fastq.gz 2.5 GB
EGAF50000188085 fastq.gz 2.1 GB
EGAF50000188086 fastq.gz 2.3 GB
EGAF50000188087 fastq.gz 2.4 GB
EGAF50000188088 fastq.gz 2.7 GB
EGAF50000188089 fastq.gz 3.7 GB
EGAF50000188090 fastq.gz 4.1 GB
EGAF50000188091 fastq.gz 1.9 GB
EGAF50000188092 fastq.gz 2.2 GB
EGAF50000188093 fastq.gz 3.0 GB
EGAF50000188094 fastq.gz 3.2 GB
EGAF50000188095 fastq.gz 2.3 GB
EGAF50000188096 fastq.gz 2.5 GB
EGAF50000188097 fastq.gz 2.6 GB
EGAF50000188098 fastq.gz 2.8 GB
EGAF50000188099 fastq.gz 2.8 GB
EGAF50000188100 fastq.gz 3.1 GB
EGAF50000188101 fastq.gz 2.8 GB
EGAF50000188102 fastq.gz 3.0 GB
EGAF50000188103 fastq.gz 2.2 GB
EGAF50000188104 fastq.gz 2.5 GB
EGAF50000188105 fastq.gz 2.7 GB
EGAF50000188106 fastq.gz 2.9 GB
EGAF50000188107 fastq.gz 2.5 GB
EGAF50000188108 fastq.gz 2.7 GB
EGAF50000188109 fastq.gz 2.7 GB
EGAF50000188110 fastq.gz 3.0 GB
EGAF50000188111 fastq.gz 2.7 GB
EGAF50000188112 fastq.gz 2.9 GB
EGAF50000188113 fastq.gz 2.0 GB
EGAF50000188114 fastq.gz 2.2 GB
EGAF50000188115 fastq.gz 2.5 GB
EGAF50000188116 fastq.gz 2.6 GB
EGAF50000188117 fastq.gz 2.8 GB
EGAF50000188118 fastq.gz 3.0 GB
EGAF50000188119 fastq.gz 2.2 GB
EGAF50000188120 fastq.gz 2.5 GB
EGAF50000188121 fastq.gz 2.3 GB
EGAF50000188122 fastq.gz 2.6 GB
EGAF50000188123 fastq.gz 2.1 GB
EGAF50000188124 fastq.gz 2.3 GB
EGAF50000188125 fastq.gz 2.1 GB
EGAF50000188126 fastq.gz 2.3 GB
EGAF50000188127 fastq.gz 1.9 GB
EGAF50000188128 fastq.gz 2.1 GB
EGAF50000188129 fastq.gz 3.4 GB
EGAF50000188130 fastq.gz 3.6 GB
EGAF50000188131 fastq.gz 2.5 GB
EGAF50000188132 fastq.gz 2.6 GB
EGAF50000188133 fastq.gz 2.4 GB
EGAF50000188134 fastq.gz 2.7 GB
EGAF50000188135 fastq.gz 2.2 GB
EGAF50000188136 fastq.gz 2.4 GB
EGAF50000188137 fastq.gz 2.6 GB
EGAF50000188138 fastq.gz 2.9 GB
EGAF50000188139 fastq.gz 2.6 GB
EGAF50000188140 fastq.gz 2.8 GB
EGAF50000188141 fastq.gz 3.0 GB
EGAF50000188142 fastq.gz 3.2 GB
EGAF50000188143 fastq.gz 2.7 GB
EGAF50000188144 fastq.gz 3.0 GB
EGAF50000188145 fastq.gz 2.1 GB
EGAF50000188146 fastq.gz 2.4 GB
EGAF50000188147 fastq.gz 2.3 GB
EGAF50000188148 fastq.gz 2.5 GB
EGAF50000188149 fastq.gz 2.4 GB
EGAF50000188150 fastq.gz 2.6 GB
EGAF50000188151 fastq.gz 2.3 GB
EGAF50000188152 fastq.gz 2.6 GB
EGAF50000188153 fastq.gz 2.4 GB
EGAF50000188154 fastq.gz 2.6 GB
EGAF50000188155 fastq.gz 2.1 GB
EGAF50000188156 fastq.gz 2.2 GB
EGAF50000188157 fastq.gz 2.9 GB
EGAF50000188158 fastq.gz 3.1 GB
EGAF50000188159 fastq.gz 3.3 GB
EGAF50000188160 fastq.gz 3.7 GB
EGAF50000188161 fastq.gz 2.4 GB
EGAF50000188162 fastq.gz 2.7 GB
190 Files (510.3 GB)