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Single cell targeted DNA-sequencing (and antibody sequencing) of high hyperdiploid B-ALL

This dataset contains all sequencing data of the publication "Single-cell DNA and Surface Protein Characterization of High Hyperdiploid Acute Lymphoblastic Leukemia at Diagnosis and During Treatment". We provide both the raw fastq-files as well as the processed data in the form of .h5 files. There are 13 patients: XJ176, XH135, XJ180, XI145, XI148, XI167, XI150, XJ175, XJ178, XI162, XF98, XG111 and XG115. Of 9 patients, also follow-up samples during/after treatment were sequenced: XJ180, XI145, XI148, XI167, XI150, XJ175, XJ178, XI162 and XG111. To identify the cell types and distinguish between normal and leukemic cells, cell surface proteins were also captured for 6 samples: XF98, XG111 (at diagnosis and during treatment), XG115, XI162 (after treatment) and XJ175 (after treatment). All samples were processed on the MissionBio platform with a custom amplicon panel, and DaB-seq for the combined targeted DNA and protein sequencing.

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This policy applies to the access to and transfer of VIB research datasets that contain non-anonymous Personal Data which are subject to the provisions of the General Data Protection Regulation (EU) 2016/679.

Applicability This policy applies to the access to and transfer of VIB research datasets that contain non-anonymous Personal Data which are subject to the provisions of the General Data Protection Regulation (EU) 2016/679. Access/transfer conditions - The access/transfer is subject to approval by the VIB Data Access Committee. - The proposed research purpose should not be incompatible with the primary research purpose for which the data were originally generated. - The Recipient shall have the necessary competence to handle such datasets. - The Recipient shall have in place adequate safeguards for the protection of Personal Data. - Access is subject to a Data Transfer/Access Agreement which will be managed by VIB Innovation & Business. - The Data Transfer/Access will be limited to the Data that are necessary for the proposed research. Access/transfer procedure - Requests to access or obtain non-anonymous datasets should be submitted to dac@vib.be with a copy to the responsible scientist that has uploaded the dataset onto the repository. - The Requestor must fill in an online request form that will gather amongst other the following information: o Name, affiliation (legal entity) and contact information of the requesting recipient party. o Reference to the specific dataset(s) for which access or transfer is requested. o Description of the research purpose for which the data will be used. - The VIB Data Access Committee will take a decision to approve access/transfer within 14 days upon receipt of the request, involving the responsible scientist. - Data access will be given / Data will be transferred subject to and after completion of a Data Transfer/Access Agreement.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000580 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF50000193581 fastq.gz 3.8 GB
EGAF50000193582 fastq 2.gz 4.2 GB
EGAF50000193583 fastq 2.gz 4.5 GB
EGAF50000193584 fastq.gz 4.5 GB
EGAF50000193585 fastq.gz 3.9 GB
EGAF50000193586 fastq 2.gz 5.2 GB
EGAF50000193587 fastq 2.gz 5.2 GB
EGAF50000193588 fastq.gz 5.1 GB
EGAF50000193589 fastq.gz 4.0 GB
EGAF50000193590 fastq 2.gz 4.1 GB
EGAF50000193591 fastq.gz 4.2 GB
EGAF50000193592 fastq 2.gz 4.6 GB
EGAF50000193593 fastq.gz 5.1 GB
EGAF50000193594 fastq.gz 4.5 GB
EGAF50000193595 fastq 2.gz 5.5 GB
EGAF50000193596 fastq 2.gz 12.5 GB
EGAF50000193597 fastq 2.gz 12.3 GB
EGAF50000193598 fastq.gz 12.6 GB
EGAF50000193599 fastq.gz 12.6 GB
EGAF50000193600 fastq.gz 12.4 GB
EGAF50000193601 fastq 2.gz 12.4 GB
EGAF50000193602 fastq 2.gz 12.1 GB
EGAF50000193603 fastq 2.gz 13.7 GB
EGAF50000193604 fastq.gz 11.9 GB
EGAF50000193605 fastq.gz 15.8 GB
EGAF50000193606 fastq 2.gz 16.5 GB
EGAF50000193607 fastq.gz 19.2 GB
EGAF50000193608 fastq 2.gz 15.0 GB
EGAF50000193609 fastq.gz 16.6 GB
EGAF50000193610 fastq 2.gz 17.6 GB
EGAF50000193611 fastq.gz 20.2 GB
EGAF50000193612 h5 519.7 MB
EGAF50000193613 fastq.gz 8.4 GB
EGAF50000193614 fastq.gz 8.8 GB
EGAF50000193615 fastq.gz 8.4 GB
EGAF50000193616 fastq.gz 8.8 GB
EGAF50000193617 h5 531.6 MB
EGAF50000193618 fastq.gz 9.0 GB
EGAF50000193619 fastq.gz 9.9 GB
EGAF50000193620 fastq.gz 9.2 GB
EGAF50000193621 fastq.gz 10.2 GB
EGAF50000193622 h5 395.5 MB
EGAF50000193623 fastq.gz 12.1 GB
EGAF50000193624 fastq.gz 13.3 GB
EGAF50000193625 h5 515.1 MB
EGAF50000193626 fastq.gz 9.4 GB
EGAF50000193627 fastq.gz 10.0 GB
EGAF50000193628 fastq.gz 9.5 GB
EGAF50000193629 fastq.gz 10.2 GB
EGAF50000193630 h5 869.7 MB
EGAF50000193631 fastq.gz 10.0 GB
EGAF50000193632 fastq.gz 12.0 GB
EGAF50000193633 fastq.gz 13.3 GB
EGAF50000193634 fastq.gz 10.9 GB
EGAF50000193635 fastq.gz 9.9 GB
EGAF50000193636 fastq.gz 10.9 GB
EGAF50000193637 h5 390.1 MB
EGAF50000193638 h5 325.2 MB
EGAF50000193639 fastq.gz 9.3 GB
EGAF50000193640 fastq.gz 10.3 GB
EGAF50000193641 fastq.gz 9.4 GB
EGAF50000193642 fastq.gz 10.5 GB
EGAF50000193643 fastq.gz 14.7 GB
EGAF50000193644 h5 371.3 MB
EGAF50000193645 fastq.gz 11.0 GB
EGAF50000193646 fastq.gz 11.9 GB
EGAF50000193647 fastq.gz 14.4 GB
EGAF50000193648 fastq.gz 14.6 GB
EGAF50000193649 fastq.gz 14.3 GB
EGAF50000193650 h5 866.2 MB
EGAF50000193651 fastq.gz 6.8 GB
EGAF50000193652 fastq.gz 7.6 GB
EGAF50000193653 fastq.gz 6.9 GB
EGAF50000193654 fastq.gz 7.8 GB
EGAF50000193655 fastq.gz 11.0 GB
EGAF50000193656 fastq.gz 11.9 GB
EGAF50000193657 h5 745.7 MB
EGAF50000193658 fastq.gz 10.4 GB
EGAF50000193659 fastq.gz 9.6 GB
EGAF50000193660 fastq.gz 10.4 GB
EGAF50000193661 fastq.gz 9.6 GB
EGAF50000193662 h5 861.8 MB
EGAF50000193663 fastq.gz 8.4 GB
EGAF50000193664 fastq.gz 8.9 GB
EGAF50000193665 fastq.gz 8.6 GB
EGAF50000193666 fastq.gz 9.1 GB
EGAF50000193667 h5 356.1 MB
EGAF50000193668 h5 387.2 MB
EGAF50000193669 h5 299.7 MB
EGAF50000193670 fastq.gz 8.3 GB
EGAF50000193671 fastq.gz 9.3 GB
EGAF50000193672 fastq.gz 8.5 GB
EGAF50000193673 fastq.gz 9.6 GB
EGAF50000193674 fastq.gz 7.2 GB
EGAF50000193675 fastq.gz 7.9 GB
EGAF50000193676 fastq.gz 7.1 GB
EGAF50000193677 fastq.gz 7.9 GB
EGAF50000193678 h5 368.7 MB
EGAF50000193679 fastq.gz 11.0 GB
EGAF50000193680 fastq.gz 12.0 GB
EGAF50000193681 fastq.gz 10.9 GB
EGAF50000193682 fastq.gz 12.0 GB
EGAF50000193683 h5 390.3 MB
EGAF50000193684 fastq.gz 8.1 GB
EGAF50000193685 fastq.gz 8.9 GB
EGAF50000193686 fastq.gz 8.2 GB
EGAF50000193687 h5 648.8 MB
EGAF50000193688 fastq.gz 9.1 GB
EGAF50000193689 h5 370.3 MB
EGAF50000193690 h5 760.9 MB
EGAF50000193691 fastq.gz 7.8 GB
EGAF50000193692 fastq.gz 8.7 GB
EGAF50000193693 fastq.gz 7.7 GB
EGAF50000193694 fastq.gz 8.6 GB
EGAF50000193695 h5 459.8 MB
EGAF50000193696 h5 1.9 GB
EGAF50000193697 fastq.gz 9.3 GB
EGAF50000193698 fastq.gz 10.5 GB
EGAF50000193699 fastq.gz 9.3 GB
EGAF50000193700 fastq.gz 2.2 GB
EGAF50000193701 h5 400.4 MB
EGAF50000193702 h5 430.9 MB
EGAF50000193703 h5 911.3 MB
EGAF50000193704 fastq.gz 8.9 GB
EGAF50000193705 fastq.gz 8.8 GB
EGAF50000193706 fastq.gz 9.2 GB
EGAF50000193707 fastq.gz 9.2 GB
EGAF50000193708 fastq.gz 2.9 GB
EGAF50000193709 fastq.gz 2.4 GB
EGAF50000193710 fastq.gz 2.8 GB
EGAF50000193711 fastq.gz 2.4 GB
EGAF50000193712 h5 337.9 MB
EGAF50000193713 h5 528.0 MB
EGAF50000193714 fastq.gz 8.0 GB
EGAF50000193715 fastq.gz 8.9 GB
EGAF50000193716 fastq.gz 8.1 GB
EGAF50000193717 fastq.gz 9.0 GB
EGAF50000193718 h5 1.3 GB
EGAF50000193719 fastq.gz 9.9 GB
EGAF50000193720 fastq.gz 10.9 GB
EGAF50000193721 fastq.gz 10.0 GB
EGAF50000193722 fastq.gz 11.0 GB
EGAF50000193723 fastq.gz 2.9 GB
EGAF50000193724 fastq.gz 2.8 GB
EGAF50000193725 fastq.gz 2.9 GB
EGAF50000193726 fastq.gz 2.8 GB
EGAF50000193727 fastq.gz 14.1 GB
EGAF50000193728 fastq.gz 16.1 GB
EGAF50000193729 fastq.gz 14.3 GB
EGAF50000193730 fastq.gz 16.2 GB
EGAF50000193731 fastq.gz 13.1 GB
EGAF50000193732 fastq.gz 14.4 GB
EGAF50000193733 fastq.gz 13.3 GB
EGAF50000193734 fastq.gz 14.5 GB
EGAF50000193735 fastq.gz 11.8 GB
EGAF50000193736 fastq.gz 10.6 GB
EGAF50000193737 fastq.gz 11.7 GB
EGAF50000193738 fastq.gz 10.5 GB
EGAF50000193739 fastq.gz 5.3 GB
EGAF50000193740 fastq.gz 4.8 GB
EGAF50000193741 fastq.gz 5.2 GB
EGAF50000193742 fastq.gz 4.7 GB
EGAF50000193743 fastq.gz 16.0 GB
EGAF50000193744 fastq.gz 18.4 GB
EGAF50000193745 fastq.gz 16.2 GB
EGAF50000193746 fastq.gz 18.7 GB
EGAF50000193747 fastq.gz 5.2 GB
EGAF50000193748 fastq.gz 5.2 GB
EGAF50000193749 fastq.gz 5.1 GB
EGAF50000193750 fastq.gz 5.1 GB
EGAF50000193751 fastq 2.gz 5.6 GB
171 Files (1.4 TB)