Human CMV-specific CD8+ T cells
In this study we established a comprehensive workflow to collect multi-omics single-cell data using a commercially available micro-well based platform. This included whole transcriptome, cell surface markers (targeted sequencing-based cell surface proteomics), T cell specificities, adaptive immune receptor repertoire (AIRR) profiles and sample multiplexing. With this technique we identified novel paired T cell receptor sequences for three prominent human CMV epitopes. In addition, we review the ability of dCODE dextramers to detect antigenspecific T cells at low frequencies by estimating sensitivities and specificities when used as reagents for single-cell multi-omics.
- 27/03/2025
- 12 samples
- DAC: EGAC50000000089
- Technology: Illumina NovaSeq 6000
DAC policy of SyMed Bonn
Access to data generated is made available by completing the data access agreement for review by the data access committee and will be granted to qualified investigators for appropriate use.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000000633 | Transcriptome Analysis |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF50000207397 | fastq.gz | 13.1 GB | ||
| EGAF50000207398 | fastq.gz | 30.0 GB | ||
| EGAF50000207399 | fastq.gz | 54.5 GB | ||
| EGAF50000207400 | fastq.gz | 133.9 GB | ||
| EGAF50000207401 | fastq.gz | 48.7 GB | ||
| EGAF50000207402 | fastq.gz | 118.6 GB | ||
| EGAF50000207403 | fastq.gz | 66.5 GB | ||
| EGAF50000207404 | fastq.gz | 177.7 GB | ||
| EGAF50000207405 | fastq.gz | 71.9 GB | ||
| EGAF50000207406 | fastq.gz | 197.2 GB | ||
| EGAF50000207407 | fastq.gz | 19.5 GB | ||
| EGAF50000207408 | fastq.gz | 56.2 GB | ||
| EGAF50000207409 | fastq.gz | 20.3 GB | ||
| EGAF50000207410 | fastq.gz | 55.7 GB | ||
| EGAF50000207411 | fastq.gz | 1.1 GB | ||
| EGAF50000207412 | fastq.gz | 3.5 GB | ||
| EGAF50000207413 | fastq.gz | 907.0 MB | ||
| EGAF50000207414 | fastq.gz | 2.9 GB | ||
| EGAF50000207415 | fastq.gz | 21.4 GB | ||
| EGAF50000207416 | fastq.gz | 52.5 GB | ||
| EGAF50000207417 | fastq.gz | 18.7 GB | ||
| EGAF50000207418 | fastq.gz | 45.9 GB | ||
| EGAF50000207419 | fastq.gz | 11.8 GB | ||
| EGAF50000207420 | fastq.gz | 27.2 GB | ||
| EGAF50000207421 | csv | 61.8 kB | ||
| 25 Files (1.2 TB) | ||||