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RNA-Seq of human longitudinal whole blood samples from PCR-positive and PCR-negative adults following controlled inoculation with Influenza A H3N2 virus.

Understanding of the transcriptomic profile of individuals in early influenza infection is limited. To investigate this, longitudinal whole-blood samples (n=178) were taken from adult participants following controlled inoculation with Influenza A H3N2 virus (sampling at baseline (0) and days 1, 2, 3, 7, 10 and 14 post-challenge). Most participants became influenza PCR-positive; a minority remained PCR-negative. Total RNA was extracted from PAXgene tubes before undergoing globin and rRNA depletion. DNA libraries were constructed using the NEBNext® Ultra™ II Directional RNA Library Prep Kit for Illumina. All samples were then sequenced using Illumina NovaSeq 6000.

Request Access

Data is available upon reasonable request to the data access committee (Prof. Christopher Chiu, and Dr Myrsini Kaforou, Imperial College London).

Data is available upon reasonable request to the data access committee (Prof. Christopher Chiu, and Dr Myrsini Kaforou, Imperial College London). Investigators will be asked to provide a short summary of how they wish to use the data in their research prior to granting access.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000679 Transcriptome Analysis

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF50000227227 fastq.gz 1.5 GB
EGAF50000227228 fastq.gz 1.5 GB
EGAF50000227229 fastq.gz 1.3 GB
EGAF50000227230 fastq.gz 1.3 GB
EGAF50000227231 fastq.gz 1.4 GB
EGAF50000227232 fastq.gz 1.3 GB
EGAF50000227233 fastq.gz 1.4 GB
EGAF50000227234 fastq.gz 1.3 GB
EGAF50000227235 fastq.gz 1.4 GB
EGAF50000227236 fastq.gz 1.5 GB
EGAF50000227237 fastq.gz 1.4 GB
EGAF50000227238 fastq.gz 1.4 GB
EGAF50000227239 fastq.gz 1.2 GB
EGAF50000227240 fastq.gz 1.3 GB
EGAF50000227241 fastq.gz 1.5 GB
EGAF50000227242 fastq.gz 1.5 GB
EGAF50000227243 fastq.gz 1.3 GB
EGAF50000227244 fastq.gz 1.4 GB
EGAF50000227245 fastq.gz 1.4 GB
EGAF50000227246 fastq.gz 1.6 GB
EGAF50000227247 fastq.gz 1.6 GB
EGAF50000227248 fastq.gz 1.3 GB
EGAF50000227249 fastq.gz 1.3 GB
EGAF50000227250 fastq.gz 1.4 GB
EGAF50000227251 fastq.gz 1.4 GB
EGAF50000227252 fastq.gz 1.0 GB
EGAF50000227253 fastq.gz 1.4 GB
EGAF50000227254 fastq.gz 1.4 GB
EGAF50000227255 fastq.gz 1.3 GB
EGAF50000227256 fastq.gz 1.4 GB
EGAF50000227257 fastq.gz 1.3 GB
EGAF50000227258 fastq.gz 1.4 GB
EGAF50000227259 fastq.gz 1.5 GB
EGAF50000227260 fastq.gz 1.2 GB
EGAF50000227261 fastq.gz 1.3 GB
EGAF50000227262 fastq.gz 1.2 GB
EGAF50000227263 fastq.gz 1.5 GB
EGAF50000227264 fastq.gz 1.4 GB
EGAF50000227265 fastq.gz 1.5 GB
EGAF50000227266 fastq.gz 1.3 GB
EGAF50000227267 fastq.gz 1.3 GB
EGAF50000227268 fastq.gz 1.4 GB
EGAF50000227269 fastq.gz 1.3 GB
EGAF50000227270 fastq.gz 1.4 GB
EGAF50000227271 fastq.gz 1.2 GB
EGAF50000227272 fastq.gz 1.2 GB
EGAF50000227273 fastq.gz 1.3 GB
EGAF50000227274 fastq.gz 1.3 GB
EGAF50000227275 fastq.gz 1.4 GB
EGAF50000227276 fastq.gz 1.4 GB
EGAF50000227277 fastq.gz 1.4 GB
EGAF50000227278 fastq.gz 1.3 GB
EGAF50000227279 fastq.gz 1.3 GB
EGAF50000227280 fastq.gz 1.5 GB
EGAF50000227281 fastq.gz 1.5 GB
EGAF50000227282 fastq.gz 1.5 GB
EGAF50000227283 fastq.gz 1.5 GB
EGAF50000227284 fastq.gz 1.4 GB
EGAF50000227285 fastq.gz 1.5 GB
EGAF50000227286 fastq.gz 1.3 GB
EGAF50000227287 fastq.gz 1.3 GB
EGAF50000227288 fastq.gz 1.4 GB
EGAF50000227289 fastq.gz 1.4 GB
EGAF50000227290 fastq.gz 1.4 GB
EGAF50000227291 fastq.gz 1.5 GB
EGAF50000227292 fastq.gz 1.5 GB
EGAF50000227293 fastq.gz 1.5 GB
EGAF50000227294 fastq.gz 1.5 GB
EGAF50000227295 fastq.gz 1.4 GB
EGAF50000227296 fastq.gz 1.5 GB
EGAF50000227297 fastq.gz 1.4 GB
EGAF50000227298 fastq.gz 1.4 GB
EGAF50000227299 fastq.gz 1.4 GB
EGAF50000227300 fastq.gz 1.4 GB
EGAF50000227301 fastq.gz 1.4 GB
EGAF50000227302 fastq.gz 1.4 GB
EGAF50000227303 fastq.gz 1.3 GB
EGAF50000227304 fastq.gz 1.3 GB
EGAF50000227305 fastq.gz 1.5 GB
EGAF50000227306 fastq.gz 1.6 GB
EGAF50000227307 fastq.gz 1.6 GB
EGAF50000227308 fastq.gz 1.7 GB
EGAF50000227309 fastq.gz 1.3 GB
EGAF50000227310 fastq.gz 1.4 GB
EGAF50000227311 fastq.gz 1.3 GB
EGAF50000227312 fastq.gz 1.3 GB
EGAF50000227313 fastq.gz 1.3 GB
EGAF50000227314 fastq.gz 1.3 GB
EGAF50000227315 fastq.gz 1.4 GB
EGAF50000227316 fastq.gz 1.4 GB
EGAF50000227317 fastq.gz 1.3 GB
EGAF50000227318 fastq.gz 1.4 GB
EGAF50000227319 fastq.gz 1.4 GB
EGAF50000227320 fastq.gz 1.3 GB
EGAF50000227321 fastq.gz 1.4 GB
EGAF50000227322 fastq.gz 1.5 GB
EGAF50000227323 fastq.gz 1.5 GB
EGAF50000227324 fastq.gz 1.5 GB
EGAF50000227325 fastq.gz 1.4 GB
EGAF50000227326 fastq.gz 1.4 GB
EGAF50000227327 fastq.gz 1.4 GB
EGAF50000227328 fastq.gz 1.4 GB
EGAF50000227329 fastq.gz 1.4 GB
EGAF50000227330 fastq.gz 1.4 GB
EGAF50000227331 fastq.gz 1.4 GB
EGAF50000227332 fastq.gz 1.4 GB
EGAF50000227333 fastq.gz 1.2 GB
EGAF50000227334 fastq.gz 1.5 GB
EGAF50000227335 fastq.gz 1.5 GB
EGAF50000227336 fastq.gz 1.4 GB
EGAF50000227337 fastq.gz 1.4 GB
EGAF50000227338 fastq.gz 1.3 GB
EGAF50000227339 fastq.gz 1.6 GB
EGAF50000227340 fastq.gz 1.4 GB
EGAF50000227341 fastq.gz 1.4 GB
EGAF50000227342 fastq.gz 1.4 GB
EGAF50000227343 fastq.gz 1.3 GB
EGAF50000227344 fastq.gz 1.4 GB
EGAF50000227345 fastq.gz 1.4 GB
EGAF50000227346 fastq.gz 1.4 GB
EGAF50000227347 fastq.gz 1.4 GB
EGAF50000227348 fastq.gz 1.5 GB
EGAF50000227349 fastq.gz 1.5 GB
EGAF50000227350 fastq.gz 1.2 GB
EGAF50000227351 fastq.gz 1.3 GB
EGAF50000227352 fastq.gz 1.4 GB
EGAF50000227353 fastq.gz 1.5 GB
EGAF50000227354 fastq.gz 1.3 GB
EGAF50000227355 fastq.gz 1.3 GB
EGAF50000227356 fastq.gz 1.3 GB
EGAF50000227357 fastq.gz 1.4 GB
EGAF50000227358 fastq.gz 1.5 GB
EGAF50000227359 fastq.gz 1.3 GB
EGAF50000227360 fastq.gz 1.3 GB
EGAF50000227361 fastq.gz 1.6 GB
EGAF50000227362 fastq.gz 1.3 GB
EGAF50000227363 fastq.gz 1.3 GB
EGAF50000227364 fastq.gz 1.6 GB
EGAF50000227365 fastq.gz 1.6 GB
EGAF50000227366 fastq.gz 1.5 GB
EGAF50000227367 fastq.gz 1.5 GB
EGAF50000227368 fastq.gz 1.3 GB
EGAF50000227369 fastq.gz 1.3 GB
EGAF50000227370 fastq.gz 1.3 GB
EGAF50000227371 fastq.gz 1.4 GB
EGAF50000227372 fastq.gz 1.3 GB
EGAF50000227373 fastq.gz 1.3 GB
EGAF50000227374 fastq.gz 1.4 GB
EGAF50000227375 fastq.gz 1.4 GB
EGAF50000227376 fastq.gz 1.3 GB
EGAF50000227377 fastq.gz 1.3 GB
EGAF50000227378 fastq.gz 1.3 GB
EGAF50000227379 fastq.gz 480.3 MB
EGAF50000227380 fastq.gz 1.3 GB
EGAF50000227381 fastq.gz 1.1 GB
EGAF50000227382 fastq.gz 1.4 GB
EGAF50000227383 fastq.gz 1.3 GB
EGAF50000227384 fastq.gz 1.4 GB
EGAF50000227385 fastq.gz 1.3 GB
EGAF50000227386 fastq.gz 1.3 GB
EGAF50000227387 fastq.gz 1.4 GB
EGAF50000227388 fastq.gz 1.4 GB
EGAF50000227389 fastq.gz 1.3 GB
EGAF50000227390 fastq.gz 1.4 GB
EGAF50000227391 fastq.gz 1.4 GB
EGAF50000227392 fastq.gz 1.3 GB
EGAF50000227393 fastq.gz 1.3 GB
EGAF50000227394 fastq.gz 1.3 GB
EGAF50000227395 fastq.gz 1.5 GB
EGAF50000227396 fastq.gz 1.4 GB
EGAF50000227397 fastq.gz 1.5 GB
EGAF50000227398 fastq.gz 1.3 GB
EGAF50000227399 fastq.gz 1.4 GB
EGAF50000227400 fastq.gz 1.6 GB
EGAF50000227401 fastq.gz 1.4 GB
EGAF50000227402 fastq.gz 1.5 GB
EGAF50000227403 fastq.gz 1.4 GB
EGAF50000227404 fastq.gz 1.3 GB
EGAF50000227405 fastq.gz 1.4 GB
EGAF50000227406 fastq.gz 1.2 GB
EGAF50000227407 fastq.gz 1.2 GB
EGAF50000227408 fastq.gz 1.3 GB
EGAF50000227409 fastq.gz 1.3 GB
EGAF50000227410 fastq.gz 1.2 GB
EGAF50000227411 fastq.gz 1.2 GB
EGAF50000227412 fastq.gz 1.4 GB
EGAF50000227413 fastq.gz 1.2 GB
EGAF50000227414 fastq.gz 1.2 GB
EGAF50000227415 fastq.gz 1.4 GB
EGAF50000227416 fastq.gz 1.5 GB
EGAF50000227417 fastq.gz 1.3 GB
EGAF50000227418 fastq.gz 1.4 GB
EGAF50000227419 fastq.gz 1.3 GB
EGAF50000227420 fastq.gz 1.3 GB
EGAF50000227421 fastq.gz 1.3 GB
EGAF50000227422 fastq.gz 1.4 GB
EGAF50000227423 fastq.gz 1.3 GB
EGAF50000227424 fastq.gz 1.3 GB
EGAF50000227425 fastq.gz 1.4 GB
EGAF50000227426 fastq.gz 1.4 GB
EGAF50000227427 fastq.gz 1.5 GB
EGAF50000227428 fastq.gz 1.5 GB
EGAF50000227429 fastq.gz 1.5 GB
EGAF50000227430 fastq.gz 1.6 GB
EGAF50000227431 fastq.gz 1.5 GB
EGAF50000227432 fastq.gz 1.5 GB
EGAF50000227433 fastq.gz 1.3 GB
EGAF50000227434 fastq.gz 1.3 GB
EGAF50000227435 fastq.gz 1.3 GB
EGAF50000227436 fastq.gz 1.3 GB
EGAF50000227437 fastq.gz 1.5 GB
EGAF50000227438 fastq.gz 1.5 GB
EGAF50000227439 fastq.gz 1.6 GB
EGAF50000227440 fastq.gz 1.4 GB
EGAF50000227441 fastq.gz 1.4 GB
EGAF50000227442 fastq.gz 1.4 GB
EGAF50000227443 fastq.gz 1.4 GB
EGAF50000227444 fastq.gz 1.7 GB
EGAF50000227445 fastq.gz 1.4 GB
EGAF50000227446 fastq.gz 1.4 GB
EGAF50000227447 fastq.gz 1.4 GB
EGAF50000227448 fastq.gz 1.4 GB
EGAF50000227449 fastq.gz 1.4 GB
EGAF50000227450 fastq.gz 1.4 GB
EGAF50000227451 fastq.gz 1.3 GB
EGAF50000227452 fastq.gz 1.5 GB
EGAF50000227453 fastq.gz 1.6 GB
EGAF50000227454 fastq.gz 1.5 GB
EGAF50000227455 fastq.gz 1.5 GB
EGAF50000227456 fastq.gz 1.4 GB
EGAF50000227457 fastq.gz 1.4 GB
EGAF50000227458 fastq.gz 1.3 GB
EGAF50000227459 fastq.gz 1.4 GB
EGAF50000227460 fastq.gz 1.4 GB
EGAF50000227461 fastq.gz 1.6 GB
EGAF50000227462 fastq.gz 1.5 GB
EGAF50000227463 fastq.gz 1.3 GB
EGAF50000227464 fastq.gz 1.4 GB
EGAF50000227465 fastq.gz 1.4 GB
EGAF50000227466 fastq.gz 1.5 GB
EGAF50000227467 fastq.gz 1.5 GB
EGAF50000227468 fastq.gz 1.5 GB
EGAF50000227469 fastq.gz 1.4 GB
EGAF50000227470 fastq.gz 1.5 GB
EGAF50000227471 fastq.gz 1.3 GB
EGAF50000227472 fastq.gz 1.3 GB
EGAF50000227473 fastq.gz 1.2 GB
EGAF50000227474 fastq.gz 1.3 GB
EGAF50000227475 fastq.gz 1.3 GB
EGAF50000227476 fastq.gz 1.7 GB
EGAF50000227477 fastq.gz 1.6 GB
EGAF50000227478 fastq.gz 1.5 GB
EGAF50000227479 fastq.gz 1.4 GB
EGAF50000227480 fastq.gz 1.4 GB
EGAF50000227481 fastq.gz 1.5 GB
EGAF50000227482 fastq.gz 1.5 GB
EGAF50000227483 fastq.gz 1.4 GB
EGAF50000227484 fastq.gz 1.4 GB
EGAF50000227485 fastq.gz 1.5 GB
EGAF50000227486 fastq.gz 1.5 GB
EGAF50000227487 fastq.gz 1.5 GB
EGAF50000227488 fastq.gz 1.3 GB
EGAF50000227489 fastq.gz 1.4 GB
EGAF50000227490 fastq.gz 1.4 GB
EGAF50000227491 fastq.gz 1.5 GB
EGAF50000227492 fastq.gz 1.3 GB
EGAF50000227493 fastq.gz 1.3 GB
EGAF50000227494 fastq.gz 1.4 GB
EGAF50000227495 fastq.gz 1.5 GB
EGAF50000227496 fastq.gz 1.4 GB
EGAF50000227497 fastq.gz 1.4 GB
EGAF50000227498 fastq.gz 1.3 GB
EGAF50000227499 fastq.gz 1.4 GB
EGAF50000227500 fastq.gz 1.3 GB
EGAF50000227501 fastq.gz 1.4 GB
EGAF50000227502 fastq.gz 1.4 GB
EGAF50000227503 fastq.gz 1.5 GB
EGAF50000227504 fastq.gz 1.4 GB
EGAF50000227505 fastq.gz 1.5 GB
EGAF50000227506 fastq.gz 1.6 GB
EGAF50000227507 fastq.gz 1.6 GB
EGAF50000227508 fastq.gz 1.5 GB
EGAF50000227509 fastq.gz 1.4 GB
EGAF50000227510 fastq.gz 1.4 GB
EGAF50000227511 fastq.gz 1.5 GB
EGAF50000227512 fastq.gz 1.5 GB
EGAF50000227513 fastq.gz 1.3 GB
EGAF50000227514 fastq.gz 1.4 GB
EGAF50000227515 fastq.gz 1.2 GB
EGAF50000227516 fastq.gz 1.2 GB
EGAF50000227517 fastq.gz 1.3 GB
EGAF50000227518 fastq.gz 1.5 GB
EGAF50000227519 fastq.gz 1.4 GB
EGAF50000227520 fastq.gz 1.5 GB
EGAF50000227521 fastq.gz 1.4 GB
EGAF50000227522 fastq.gz 1.4 GB
EGAF50000227523 fastq.gz 1.5 GB
EGAF50000227524 fastq.gz 1.3 GB
EGAF50000227525 fastq.gz 1.3 GB
EGAF50000227526 fastq.gz 1.7 GB
EGAF50000227527 fastq.gz 1.4 GB
EGAF50000227528 fastq.gz 1.5 GB
EGAF50000227529 fastq.gz 1.5 GB
EGAF50000227530 fastq.gz 1.4 GB
EGAF50000227531 fastq.gz 1.4 GB
EGAF50000227532 fastq.gz 1.4 GB
EGAF50000227533 fastq.gz 1.4 GB
EGAF50000227534 fastq.gz 1.4 GB
EGAF50000227535 fastq.gz 1.5 GB
EGAF50000227536 fastq.gz 1.5 GB
EGAF50000227537 fastq.gz 1.5 GB
EGAF50000227538 fastq.gz 1.5 GB
EGAF50000227539 fastq.gz 1.6 GB
EGAF50000227540 fastq.gz 1.2 GB
EGAF50000227541 fastq.gz 1.2 GB
EGAF50000227542 fastq.gz 1.3 GB
EGAF50000227543 fastq.gz 1.3 GB
EGAF50000227544 fastq.gz 1.4 GB
EGAF50000227545 fastq.gz 1.4 GB
EGAF50000227546 fastq.gz 1.4 GB
EGAF50000227547 fastq.gz 1.5 GB
EGAF50000227548 fastq.gz 1.4 GB
EGAF50000227549 fastq.gz 1.3 GB
EGAF50000227550 fastq.gz 1.3 GB
EGAF50000227551 fastq.gz 1.3 GB
EGAF50000227552 fastq.gz 1.3 GB
EGAF50000227553 fastq.gz 1.3 GB
EGAF50000227554 fastq.gz 1.4 GB
EGAF50000227555 fastq.gz 1.5 GB
EGAF50000227556 fastq.gz 1.5 GB
EGAF50000227557 fastq.gz 1.2 GB
EGAF50000227558 fastq.gz 1.3 GB
EGAF50000227559 fastq.gz 1.4 GB
EGAF50000227560 fastq.gz 1.4 GB
EGAF50000227561 fastq.gz 1.3 GB
EGAF50000227562 fastq.gz 1.3 GB
EGAF50000227563 fastq.gz 1.3 GB
EGAF50000227564 fastq.gz 1.4 GB
EGAF50000227565 fastq.gz 1.2 GB
EGAF50000227566 fastq.gz 1.4 GB
EGAF50000227567 fastq.gz 1.3 GB
EGAF50000227568 fastq.gz 1.3 GB
EGAF50000227569 fastq.gz 1.4 GB
EGAF50000227570 fastq.gz 1.5 GB
EGAF50000227571 fastq.gz 1.5 GB
EGAF50000227572 fastq.gz 1.5 GB
EGAF50000227573 fastq.gz 1.4 GB
EGAF50000227574 fastq.gz 1.3 GB
EGAF50000227575 fastq.gz 1.5 GB
EGAF50000227576 fastq.gz 1.2 GB
EGAF50000227577 fastq.gz 1.3 GB
EGAF50000227578 fastq.gz 1.2 GB
EGAF50000227579 fastq.gz 1.3 GB
EGAF50000227580 fastq.gz 1.3 GB
EGAF50000227581 fastq.gz 1.4 GB
EGAF50000227582 fastq.gz 1.5 GB
356 Files (494.3 GB)