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WES Breast Patient-derived Tumor Organoid

This dataset includes 18 Whole Exome Sequencing (WES) samples from 5 subjects. WES is performed on a matched pair of case/control samples, e.g., tumor/control or organoid/control. For each patient, the same control sample is used for the analysis of tumor and organoid samples. The sample name structure identifies the type of sample: <subjectId>_[TON][12]_[Case|Ctrl]_EX2; where T, O, and N refer to Tumor tissue, Organoid, and control sample, respectively. The number 1 or 2 refers to the specific tissue, and Case and Ctrl indicate a tumor tissue (or organoid) and a control sample, respectively. For example, ICSBCS007_T1_Case_EX2 is the first tumor tissue of subject ICSBCS007; ICSBCS007_O1_Case_EX2 is the tumor organoid derived from that tumor sample, and ICSBCS007_N1_Ctrl_EX2 is the matching control sample. More information can be found in the sample information table.

Request Access

DUO:0000021
version: 2019-01-07

ethics approval required

This data use modifier indicates that the requestor must provide documentation of local IRB/ERB approval.

DUO:0000042
version: 2019-01-07

general research use

This data use permission indicates that use is allowed for general research use for any research purpose.

This dataset is provided to You in accordance to the policy terms.

Terms and Conditions In signing this Agreement: 1. You, the Data Recipient, agree to only use the Data for the Purpose of the Project. 2. You agree to preserve, at all times, the confidentiality of information and Data pertaining to Data Subjects. You undertake not to use or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy. 3. You agree not to attempt to identify Data Subjects. 4. You and your Authorised Personnel agree to take into consideration any usage restrictions (if any), stemming from consent, i.e. the appropriate lawful basis for processing the Data, as well as any usage restrictions stemming from any applicable internal policies of your Institution. 5. You agree that in handling this Data You will follow an up-to-date information technology (IT) policy that must include, at a minimum, the following items: a. Logging and auditing of Access to the Data and to the computer network; b. Password protection to computer network and/or strong data encryption; c. Virus and malware protection to computers on the computer network; d. Secure backup procedure; 6. You acknowledge that Access to the Data is granted for the duration of the Project described in Section I, as well as any new Project under the same research field or area. Any use of the Data for a Project of another research field or area will need to be approved under a new Agreement. 7. You recognize that nothing in this Agreement shall operate to transfer to You any intellectual property rights to the Data. 8. You agree not to make intellectual property claims on the Data and not to use intellectual property protection in ways that would prevent or block Access to, or use of, any element of the Data. 9. You can elect to perform further Research that would add intellectual and resource capital to the Data, and decide to obtain intellectual property rights on these downstream discoveries. In this case, You agree to implement licensing policies that will not obstruct further Research, following the Organisation for Economic Co-operation and Development Guidelines. 10. You agree that the Research Project 1) bears no legal responsibility for the accuracy or comprehensiveness of the Data; 2) accepts no liability for indirect, consequential, or incidental damages or losses arising from use of the Data; and 3) bears no responsibility for the further analysis or interpretation of these Data over and above that published by the Controller(s). 11. You agree to hold the Data Subject(s) and Data Controller(s) harmless and to defend and indemnify all these parties against all liabilities, demands, damages, expenses, and losses arising out of Your use for any Purpose of the Data. 12. You agree to a moratorium on publishing global analyses of the dataset until the Data Controller(s) have published their own global analysis or twelve (12) months, the maximum, have passed from the time the Data were deposited, whichever occurs first. You acknowledge that prompt publication or public disclosure of the results of the Research Project is encouraged. You also agree that by publishing Your global analyses of the Data, you will not disclose any results generated from the Data. 13. You agree to acknowledge the contribution of the Data Controller(s) in all oral and written presentations, disclosures, and Publications resulting from all analyses of the Data. 14. You agree to use the Data in Your laboratory. Any Authorised Personnel shall work under Your direct supervision. You agree to distribute a copy of these terms to the Authorised Personnel. 15. You may not transfer any information included in the Data to anyone unless specifically designated in the Research Project, or by prior specific or general written authorisation of the Data Controller(s) responsible for the generation of the original Data in each case. 16. You may not transfer the Data itself to anyone outside the Institution, unless the Controller(s) has (have) approved such transfer and its terms in writing. 17. Should You wish to share the Data with an external collaborator, the external collaborator must complete a separate Data Access Agreement. 18. You shall ensure that ‘all’ who have Access to the Data, namely You and Your Authorised Personnel, will be listed out, and are made aware and be bound by the terms of this Agreement. You remain solely and fully responsible for Your Authorised Personnel’s non-compliance with the provision of the Agreement and/or applicable laws. 19. In case of a breach of security resulting from ‘accidental’ use of Data by You and Your Authorised Personnel, which leads to disclosure of Data, then You must report this to Data Controller(s) within 72 hours maximum, and follow any relevant rule as provided by the GDPR. 20. In case of a ‘non-accidental or minor’ breach of hDAA by You, You will further be required to destroy any Data held. 21. You accept that this Agreement will terminate immediately upon ‘any’ breach by You, or its termination (see Section I). 22. You endeavour to settle any dispute with the Data Controller(s) amicably. If you are unable to reach an Agreement, you will meet and negotiate in good faith in an effort to resolve the issue. If the issue has not been resolved within a reasonable period (e.g. 30 calendar days), you are both entitled to submit it for resolution by an arbitrator. 23. Further, the language of the proceedings will be ‘English’ if not otherwise agreed. The award of the arbitration will be final and binding upon the parties concerned.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000684 Exome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF00008579250 fastq.gz 4.3 GB Report
EGAF00008579251 fastq.gz 4.4 GB Report
EGAF00008579252 fastq.gz 4.3 GB Report
EGAF00008579253 fastq.gz 4.4 GB Report
EGAF00008579254 fastq.gz 3.9 GB Report
EGAF00008579255 fastq.gz 4.4 GB Report
EGAF00008579256 fastq.gz 4.5 GB Report
EGAF00008579257 fastq.gz 4.4 GB Report
EGAF00008579258 fastq.gz 4.5 GB Report
EGAF00008579261 fastq.gz 3.6 GB Report
EGAF00008579262 fastq.gz 3.6 GB Report
EGAF00008579263 fastq.gz 3.9 GB Report
EGAF00008579264 fastq.gz 3.5 GB Report
EGAF00008579265 fastq.gz 3.6 GB Report
EGAF00008579266 fastq.gz 3.6 GB Report
EGAF00008579267 fastq.gz 3.5 GB Report
EGAF00008579268 fastq.gz 3.6 GB Report
EGAF00008579269 fastq.gz 3.8 GB Report
EGAF00008579270 fastq.gz 3.5 GB Report
EGAF00008579271 fastq.gz 3.9 GB Report
EGAF00008579274 fastq.gz 3.9 GB Report
EGAF00008579275 fastq.gz 3.6 GB Report
EGAF00008579276 fastq.gz 3.6 GB Report
EGAF00008579277 fastq.gz 3.6 GB Report
EGAF00008579278 fastq.gz 3.7 GB Report
EGAF00008579279 fastq.gz 3.7 GB Report
EGAF00008579280 fastq.gz 4.1 GB Report
EGAF00008579281 fastq.gz 3.8 GB Report
EGAF00008579282 fastq.gz 3.6 GB Report
EGAF00008579283 fastq.gz 3.9 GB Report
EGAF00008579284 fastq.gz 4.0 GB Report
EGAF00008579285 fastq.gz 3.8 GB Report
EGAF00008579286 fastq.gz 3.9 GB Report
EGAF00008579287 fastq.gz 3.9 GB Report
EGAF00008579288 fastq.gz 4.0 GB Report
EGAF00008579289 fastq.gz 3.9 GB Report
EGAF00008579290 fastq.gz 3.9 GB Report
EGAF00008579292 fastq.gz 4.0 GB Report
EGAF00008579293 fastq.gz 4.0 GB Report
EGAF00008579294 fastq.gz 3.7 GB Report
EGAF00008579295 fastq.gz 3.5 GB Report
EGAF00008579296 fastq.gz 3.7 GB Report
EGAF00008579297 fastq.gz 3.6 GB Report
EGAF00008579298 fastq.gz 3.9 GB Report
EGAF00008579299 fastq.gz 3.8 GB Report
EGAF00008579300 fastq.gz 3.7 GB Report
EGAF00008579301 fastq.gz 3.5 GB Report
EGAF00008579302 fastq.gz 3.8 GB Report
EGAF00008579303 fastq.gz 3.8 GB Report
EGAF00008579304 fastq.gz 4.0 GB Report
EGAF00008579305 fastq.gz 3.5 GB Report
EGAF00008579306 fastq.gz 3.8 GB Report
EGAF00008579307 fastq.gz 3.8 GB Report
EGAF00008579309 fastq.gz 3.4 GB Report
EGAF00008579310 fastq.gz 3.5 GB Report
EGAF00008579311 fastq.gz 3.4 GB Report
EGAF00008579312 fastq.gz 3.6 GB Report
EGAF00008579313 fastq.gz 3.4 GB Report
EGAF00008579314 fastq.gz 3.5 GB Report
EGAF00008579315 fastq.gz 3.5 GB Report
EGAF00008579316 fastq.gz 3.4 GB Report
EGAF00008579318 fastq.gz 3.4 GB Report
EGAF00008579319 fastq.gz 3.5 GB Report
EGAF00008579320 fastq.gz 3.6 GB Report
EGAF00008579321 fastq.gz 3.9 GB Report
EGAF00008579322 fastq.gz 3.6 GB Report
EGAF00008579323 fastq.gz 3.6 GB Report
EGAF00008579324 fastq.gz 3.6 GB Report
EGAF00008579325 fastq.gz 3.6 GB Report
EGAF00008579326 fastq.gz 3.4 GB Report
EGAF00008579328 fastq.gz 4.3 GB Report
EGAF00008579330 fastq.gz 3.3 GB Report
EGAF00008579331 fastq.gz 4.4 GB Report
EGAF00008579332 fastq.gz 4.5 GB Report
EGAF00008579333 fastq.gz 3.4 GB Report
EGAF00008579334 fastq.gz 4.6 GB Report
EGAF00008579335 fastq.gz 4.0 GB Report
EGAF00008579337 fastq.gz 4.6 GB Report
EGAF00008579339 fastq.gz 3.4 GB Report
EGAF00008579340 fastq.gz 3.5 GB Report
EGAF00008579341 fastq.gz 3.9 GB Report
EGAF00008579342 fastq.gz 2.9 GB Report
EGAF00008579343 fastq.gz 4.8 GB Report
EGAF00008579344 fastq.gz 5.0 GB Report
EGAF00008579345 fastq.gz 4.8 GB Report
EGAF00008579346 fastq.gz 3.5 GB Report
EGAF00008579347 fastq.gz 4.4 GB Report
EGAF00008579348 fastq.gz 3.5 GB Report
EGAF00008579349 fastq.gz 3.7 GB Report
EGAF00008579350 fastq.gz 4.5 GB Report
EGAF00008579352 fastq.gz 3.7 GB Report
EGAF00008579353 fastq.gz 4.5 GB Report
EGAF00008587146 fastq.gz 3.7 GB Report
EGAF00008587147 fastq.gz 3.8 GB Report
EGAF00008587148 fastq.gz 3.9 GB Report
EGAF00008587149 fastq.gz 4.1 GB Report
EGAF00008587150 fastq.gz 3.8 GB Report
EGAF00008587152 fastq.gz 3.7 GB Report
EGAF00008587153 fastq.gz 3.6 GB Report
EGAF00008587155 fastq.gz 4.0 GB Report
EGAF00008587157 fastq.gz 3.7 GB Report
EGAF00008587159 fastq.gz 3.9 GB Report
EGAF00008587160 fastq.gz 3.9 GB Report
EGAF00008587161 fastq.gz 3.8 GB Report
EGAF00008587162 fastq.gz 4.0 GB Report
EGAF00008587163 fastq.gz 4.1 GB Report
EGAF00008587164 fastq.gz 3.8 GB Report
EGAF00008587168 fastq.gz 3.9 GB Report
EGAF00008587187 fastq.gz 4.0 GB Report
EGAF00008587199 fastq.gz 3.7 GB Report
EGAF00008587200 fastq.gz 4.0 GB Report
EGAF00008587287 fastq.gz 3.6 GB Report
EGAF00008587316 fastq.gz 3.1 GB Report
EGAF00008587317 fastq.gz 3.5 GB Report
EGAF00008587318 fastq.gz 3.0 GB Report
EGAF00008587319 fastq.gz 3.5 GB Report
EGAF00008589785 fastq.gz 3.3 GB Report
EGAF00008589786 fastq.gz 3.4 GB Report
EGAF00008589796 fastq.gz 4.7 GB Report
EGAF00008589853 fastq.gz 3.0 GB Report
EGAF00008614370 fastq.gz 3.7 GB Report
EGAF00008614371 fastq.gz 3.8 GB Report
EGAF00008614372 fastq.gz 3.8 GB Report
EGAF00008614373 fastq.gz 3.9 GB Report
EGAF00008614374 fastq.gz 3.8 GB Report
EGAF00008614375 fastq.gz 3.9 GB Report
EGAF00008614376 fastq.gz 3.7 GB Report
EGAF00008614377 fastq.gz 3.9 GB Report
EGAF00008614646 fastq.gz 4.0 GB Report
EGAF00008614647 fastq.gz 3.9 GB Report
EGAF00008614648 fastq.gz 3.9 GB Report
EGAF00008614649 fastq.gz 4.0 GB Report
132 Files (503.8 GB)