RNA sequencing data from 10 patient derived colorectal cancer organoids
This dataset comprises RNA-sequencing data from ten colorectal cancer (CRC) organoids, derived from histologically verified primary tumor tissues of patients undergoing surgical resection. Paired-end sequencing produced 20 FASTQ.gz files. The organoids were cultured in Geltrex-based droplets using PDO culture medium and harvested for RNA extraction. Total RNA was isolated and subjected to full-length mRNA sequencing, producing high-quality RNA-seq data. The dataset includes transcriptomic profiles of seven microsatellite stable (MSS) and three microsatellite instable (MSI) tumors, providing a valuable resource for the analysis of non-canonical tumor-specific antigens (ncTSAs) using the NovumRNA pipeline. This dataset aids in uncovering potential immunotherapy targets in CRC, particularly in hard-to-treat low-TMB MSS cases.
- 19/11/2024
- 10 samples
- DAC: EGAC50000000406
- Technology: Illumina NovaSeq X
- HMB DUO:0000006 (version: 2021-02-23)health or medical or biomedical researchThis data use permission indicates that use is allowed for health/medical/biomedical purposes; does not include the study of population origins or ancestry.
- NCU DUO:0000046 (version: 2021-02-23)non-commercial use onlyThis data use modifier indicates that use of the data is limited to not-for-profit use.
ICBI Data Access Agreement NovumRNA
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000000685 | RNASeq |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF50000227808 | fastq.gz | 9.3 GB | ||
| EGAF50000227809 | fastq.gz | 9.5 GB | ||
| EGAF50000227810 | fastq.gz | 6.8 GB | ||
| EGAF50000227811 | fastq.gz | 7.0 GB | ||
| EGAF50000227812 | fastq.gz | 16.6 GB | ||
| EGAF50000227813 | fastq.gz | 17.4 GB | ||
| EGAF50000227814 | fastq.gz | 15.5 GB | ||
| EGAF50000227815 | fastq.gz | 15.0 GB | ||
| EGAF50000227816 | fastq.gz | 17.8 GB | ||
| EGAF50000227817 | fastq.gz | 18.5 GB | ||
| EGAF50000227818 | fastq.gz | 15.5 GB | ||
| EGAF50000227819 | fastq.gz | 16.3 GB | ||
| EGAF50000227820 | fastq.gz | 7.3 GB | ||
| EGAF50000227821 | fastq.gz | 7.5 GB | ||
| EGAF50000227822 | fastq.gz | 13.3 GB | ||
| EGAF50000227823 | fastq.gz | 14.1 GB | ||
| EGAF50000227824 | fastq.gz | 12.0 GB | ||
| EGAF50000227825 | fastq.gz | 11.6 GB | ||
| EGAF50000227826 | fastq.gz | 8.2 GB | ||
| EGAF50000227827 | fastq.gz | 8.5 GB | ||
| 20 Files (247.8 GB) | ||||