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Dataset of scRNAseq from 56 CRC, treatment-naive and post-chemotherapy

The dataset includes FASTQ source files of scRNA-seq for 56 CRC patients, sequenced with Illumina 10x platform. All patients were diagnosed with colorectal cancer between 2014 and 2022 at the Gustave Roussy Institute. Cohort includes 32 samples from untreated patients and 24 samples from patients who received chemotherapy. Chemotherapy included FOLFOX or FOLFIRI as first line, in some cases in combination with anti-VEGF or anti-EGRF drugs (avastin, bevacizumab or cetuximab) as the second and third lines. The post-treatment cohort included 18 responders (partial response, stable disease and complete response) and 6 progressors (progressive disease).

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Single-cell Transcriptome Profiling of Post-treatment versus Treatment-naïve Colorectal Cancer: Insights into Putative Mechanisms of Chemoresistance

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorized Personnel: The individuals at the User Institution to whom the Data Access Committee grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorized Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: The individuals, listed in Appendix I, responsible for the development, organization, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution(s) that has requested access to the Data (detailed in Appendix II). Data Producers Institution(s): The Institution(s) that has produced the Data (detailed in Appendix I). Data Access Committee: The committee responsible for authorizing access to the data. Committee members are listed in Appendix I. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorized Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (https://www.sanger.ac.uk/wp-content/uploads/fortlauderdalereport.pdf) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognizing the contribution of the Data Producers and including a proper acknowledgment in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analyzing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.ott.nih.gov/sites/default/files/documents/pdfs/70fr18413.pdf) in conformity with the Organization for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (https://www.oecd.org/sti/emerging-tech/36198812.pdf). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify the Data Access Committee within 30 days of any changes or departures of Authorized Personnel. 13. The User Institution will notify the Data Access Committee prior to any significant changes to the protocol for the Project. 14. The User Institution will notify the Data Access Committee as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. The Data Access Committee may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorized Personnel. The User Institution will procure that the Authorized Personnel comply with the terms of this agreement. 19.This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of France and shall be subject to the exclusive jurisdiction of the France courts. Agreed for User Institution (Name, Title, Date, Signature): Principal Investigator (Name, Title, Date, Signature): I confirm that I have read and understood this Agreement. Agreed for the Data Access Committee (Name, Title, Date, Signature): APPENDIX I – DATASET DETAILS & DATA ACCESS COMMITTEE APPENDIX II – PROJECT DETAILS APPENDIX III – PUBLICATION POLICY APPENDIX I – DATASET DETAILS & DATA ACCESS COMMITTEE Dataset reference (EGA Study ID, Dataset Accession Numbers and Dataset Details): Name of the project that created the dataset : Single-cell Transcriptome Profiling of Post-treatment versus Treatment-naïve Colorectal Cancer: Insights into Putative Mechanisms of Chemoresistance Data Producers Institution(s): Gustave Roussy, 114, rue Edouard Vaillant – 94805 VILLEJUIF Cedex, FRANCE Names of other data producers/collaborators (Name, Email, Job Title): Sergey Nikolaev, (Sergey.NIKOLAEV@gustaveroussy.fr), Team leader, Antoine Hollebecque, (Antoine.HOLLEBECQUE@gustaveroussy.fr), Senior medical oncologist Grigory Puzanov, (Grigory.PUZANOV@gustaveroussy.fr), Postdoctoral Researcher Specific limitations on areas of research: File access: Data can be held in unencrypted files on an institutional compute system, with Unix user group read/write access for one or more appropriate groups but not Unix world read/write access behind a secure firewall. Laptops holding these data should have password protected logins and screenlocks (set to lock after 5 min of inactivity). If held on USB keys or other portable hard drives, the data must be encrypted. Name of the Data Access Committee: Sergey Nikolaev (Sergey.NIKOLAEV@gustaveroussy.fr) Antoine Hollebecque (Antoine.HOLLEBECQUE@gustaveroussy.fr) Fabrice Andre (FABRICE.ANDRE@gustaveroussy.fr) Data Access Committee Members (Name, Email, Job Title): Sergey Nikolaev, (Sergey.NIKOLAEV@gustaveroussy.fr), Team leader Principal Investigator Head of Bioinformatics platform Marc Deloger (Marc.DELOGER@gustaveroussy.fr) Bio-informatician Grigory Puzanov, (Grigory.PUZANOV@gustaveroussy.fr), Postdoctoral Researcher Data Manager Grigory Puzanov, (Grigory.PUZANOV@gustaveroussy.fr), Postdoctoral Researcher Data Protection Officer Clara BECHET (Clara.BECHET@gustaveroussy.fr) APPENDIX II – PROJECT DETAILS (to be completed by the Requestor) Details of dataset requested i.e., EGA Study and Dataset Accession Number: Brief abstract of the Project in which the Data will be used (500 words max): Drug resistance remains a major clinical challenge in the treatment of colorectal cancer (CRC) with conventional chemotherapy. Analyzing changes within tumor cells and tumor microenvironment (TME) after treatment and in metastases is essential to understanding how resistance develops. In this study, we analyzed scRNA-seq data from 56 CRCs including treatment-naïve tumors and tumors treated with standard chemotherapy with the known response status (18 responders and 6 progressors). In our cohort, primary left-sided CRCs were associated with metastatic potential mesenchymal phenotype and with depleted B cells. In the post-treatment CRC, there was a high prevalence of dendritic cells (DC) in the TME in the response group. The DC-derived signature was associated with better survival in a large CRC cohort from the TCGA. In progressors there was an enrichment of pericyte-like fibroblasts, which appeared to be associated with poor survival in a CRC-TCGA cohort. Progressors also showed elevated fractions of exhausted CD8+ T memory cells suggesting a pro-inflammatory TME. In tumor cells of progressors group, we identified specific expression of chemo-protective markers MTRNR2L1 and CDX1; and their co-expression with stemness-related immune-checkpoint CD24. In summary, scRNA-seq provides a valuable information for the discovery of prognostic markers, and reveals distinct features potentially underlying response to chemotherapy or disease progression in CRC. User Institution(s): All Individuals who the User Institution to be named as registered users (Name, Email, Job Title, Supervisor): All Individuals that should have an account created at the EGA (Name, Email, Job Title): APPENDIX III – PUBLICATION POLICY The Data Access Committee anticipates that the dataset could be useful to other qualified researchers for a variety of purposes. However, some areas of work are subject to a publication moratorium. The publication moratorium covers any publications (including oral communications) that describe the use of the dataset. For research papers, submission for publication should not occur until the Data Access Committee have published their own global analysis or twelve (12) months after these data were first made available on the relevant hosting database, unless the Data Access Committee has provided written consent to earlier submission. In any publications based on these data, please describe how the data can be accessed, including the name of the hosting database (e.g., The European Genome-phenome Archive at the European Bioinformatics Institute) and its accession numbers (e.g., EGAS00000000029), and acknowledge its use in a form agreed by the User Institution with the Data Access Committee.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000830 Transcriptome Analysis

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF50000309615 fastq.gz 436.9 MB
EGAF50000309616 fastq.gz 475.7 MB
EGAF50000309617 fastq.gz 1.4 GB
EGAF50000309618 fastq.gz 2.8 GB
EGAF50000309619 fastq.gz 564.3 MB
EGAF50000309620 fastq.gz 610.5 MB
EGAF50000309621 fastq.gz 1.9 GB
EGAF50000309622 fastq.gz 4.1 GB
EGAF50000309623 fastq.gz 637.6 MB
EGAF50000309624 fastq.gz 2.0 GB
EGAF50000309625 fastq.gz 4.6 GB
EGAF50000309626 fastq.gz 665.4 MB
EGAF50000309627 fastq.gz 4.4 GB
EGAF50000309628 fastq.gz 566.7 MB
EGAF50000309629 fastq.gz 710.1 MB
EGAF50000309630 fastq.gz 2.0 GB
EGAF50000309631 fastq.gz 665.3 MB
EGAF50000309632 fastq.gz 806.0 MB
EGAF50000309633 fastq.gz 2.2 GB
EGAF50000309634 fastq.gz 4.4 GB
EGAF50000309635 fastq.gz 647.4 MB
EGAF50000309636 fastq.gz 4.6 GB
EGAF50000309637 fastq.gz 784.9 MB
EGAF50000309638 fastq.gz 2.4 GB
EGAF50000309639 fastq.gz 4.1 GB
EGAF50000309640 fastq.gz 657.8 MB
EGAF50000309641 fastq.gz 644.3 MB
EGAF50000309642 fastq.gz 1.8 GB
EGAF50000309643 fastq.gz 4.4 GB
EGAF50000309644 fastq.gz 658.5 MB
EGAF50000309645 fastq.gz 699.5 MB
EGAF50000309646 fastq.gz 2.0 GB
EGAF50000309647 fastq.gz 715.5 MB
EGAF50000309648 fastq.gz 801.1 MB
EGAF50000309649 fastq.gz 2.5 GB
EGAF50000309650 fastq.gz 5.0 GB
EGAF50000309651 fastq.gz 350.4 MB
EGAF50000309652 fastq.gz 361.1 MB
EGAF50000309653 fastq.gz 2.2 GB
EGAF50000309654 fastq.gz 1.1 GB
EGAF50000309655 fastq.gz 336.7 MB
EGAF50000309656 fastq.gz 344.2 MB
EGAF50000309657 fastq.gz 2.3 GB
EGAF50000309658 fastq.gz 1.1 GB
EGAF50000309659 fastq.gz 266.9 MB
EGAF50000309660 fastq.gz 303.5 MB
EGAF50000309661 fastq.gz 820.6 MB
EGAF50000309662 fastq.gz 1.8 GB
EGAF50000309663 fastq.gz 304.7 MB
EGAF50000309664 fastq.gz 938.3 MB
EGAF50000309665 fastq.gz 302.3 MB
EGAF50000309666 fastq.gz 2.0 GB
EGAF50000309667 fastq.gz 341.8 MB
EGAF50000309668 fastq.gz 366.3 MB
EGAF50000309669 fastq.gz 1.1 GB
EGAF50000309670 fastq.gz 2.4 GB
EGAF50000309671 fastq.gz 390.3 MB
EGAF50000309672 fastq.gz 435.3 MB
EGAF50000309673 fastq.gz 1.3 GB
EGAF50000309674 fastq.gz 2.9 GB
EGAF50000309675 fastq.gz 2.2 GB
EGAF50000309676 fastq.gz 666.9 MB
EGAF50000309677 fastq.gz 770.0 MB
EGAF50000309678 fastq.gz 4.9 GB
EGAF50000309679 fastq.gz 406.9 MB
EGAF50000309680 fastq.gz 398.4 MB
EGAF50000309681 fastq.gz 1.3 GB
EGAF50000309682 fastq.gz 2.9 GB
EGAF50000309683 fastq.gz 1.4 GB
EGAF50000309684 fastq.gz 2.9 GB
EGAF50000309685 fastq.gz 440.6 MB
EGAF50000309686 fastq.gz 479.0 MB
EGAF50000309687 fastq.gz 4.1 GB
EGAF50000309688 fastq.gz 565.4 MB
EGAF50000309689 fastq.gz 618.0 MB
EGAF50000309690 fastq.gz 1.9 GB
EGAF50000309691 fastq.gz 639.9 MB
EGAF50000309692 fastq.gz 676.0 MB
EGAF50000309693 fastq.gz 2.0 GB
EGAF50000309694 fastq.gz 4.6 GB
EGAF50000309695 fastq.gz 568.8 MB
EGAF50000309696 fastq.gz 717.1 MB
EGAF50000309697 fastq.gz 2.0 GB
EGAF50000309698 fastq.gz 4.4 GB
EGAF50000309699 fastq.gz 667.1 MB
EGAF50000309700 fastq.gz 812.5 MB
EGAF50000309701 fastq.gz 2.2 GB
EGAF50000309702 fastq.gz 4.4 GB
EGAF50000309703 fastq.gz 793.8 MB
EGAF50000309704 fastq.gz 650.2 MB
EGAF50000309705 fastq.gz 2.4 GB
EGAF50000309706 fastq.gz 4.6 GB
EGAF50000309707 fastq.gz 402.7 MB
EGAF50000309708 fastq.gz 451.1 MB
EGAF50000309709 fastq.gz 1.3 GB
EGAF50000309710 fastq.gz 2.7 GB
EGAF50000309711 fastq.gz 459.9 MB
EGAF50000309712 fastq.gz 474.9 MB
EGAF50000309713 fastq.gz 1.3 GB
EGAF50000309714 fastq.gz 2.9 GB
EGAF50000309715 fastq.gz 351.9 MB
EGAF50000309716 fastq.gz 415.2 MB
EGAF50000309717 fastq.gz 1.1 GB
EGAF50000309718 fastq.gz 2.4 GB
EGAF50000309719 fastq.gz 349.1 MB
EGAF50000309720 fastq.gz 399.8 MB
EGAF50000309721 fastq.gz 1.1 GB
EGAF50000309722 fastq.gz 2.4 GB
EGAF50000309723 fastq.gz 417.1 MB
EGAF50000309724 fastq.gz 1.1 GB
EGAF50000309725 fastq.gz 2.4 GB
EGAF50000309726 fastq.gz 368.6 MB
EGAF50000309727 fastq.gz 378.1 MB
EGAF50000309728 fastq.gz 415.8 MB
EGAF50000309729 fastq.gz 1.2 GB
EGAF50000309730 fastq.gz 2.5 GB
EGAF50000309731 fastq.gz 422.9 MB
EGAF50000309732 fastq.gz 410.1 MB
EGAF50000309733 fastq.gz 1.2 GB
EGAF50000309734 fastq.gz 2.6 GB
EGAF50000309735 fastq.gz 214.1 MB
EGAF50000309736 fastq.gz 689.9 MB
EGAF50000309737 fastq.gz 214.8 MB
EGAF50000309738 fastq.gz 1.1 GB
EGAF50000309739 fastq.gz 689.9 MB
EGAF50000309740 fastq.gz 4.4 GB
EGAF50000309741 fastq.gz 2.3 GB
EGAF50000309742 fastq.gz 719.9 MB
EGAF50000309743 fastq.gz 629.2 MB
EGAF50000309744 fastq.gz 742.7 MB
EGAF50000309745 fastq.gz 2.1 GB
EGAF50000309746 fastq.gz 4.0 GB
EGAF50000309747 fastq.gz 4.4 GB
EGAF50000309748 fastq.gz 702.0 MB
EGAF50000309749 fastq.gz 806.6 MB
EGAF50000309750 fastq.gz 2.3 GB
EGAF50000309751 fastq.gz 773.8 MB
EGAF50000309752 fastq.gz 901.4 MB
EGAF50000309753 fastq.gz 2.6 GB
EGAF50000309754 fastq.gz 5.1 GB
EGAF50000309755 fastq.gz 664.3 MB
EGAF50000309756 fastq.gz 737.3 MB
EGAF50000309757 fastq.gz 2.2 GB
EGAF50000309758 fastq.gz 4.1 GB
EGAF50000309759 fastq.gz 715.1 MB
EGAF50000309760 fastq.gz 697.9 MB
EGAF50000309761 fastq.gz 2.0 GB
EGAF50000309762 fastq.gz 3.9 GB
EGAF50000309763 fastq.gz 695.1 MB
EGAF50000309764 fastq.gz 687.3 MB
EGAF50000309765 fastq.gz 2.2 GB
EGAF50000309766 fastq.gz 4.2 GB
EGAF50000309767 fastq.gz 603.7 MB
EGAF50000309768 fastq.gz 2.0 GB
EGAF50000309769 fastq.gz 4.4 GB
EGAF50000309770 fastq.gz 644.4 MB
EGAF50000309771 fastq.gz 4.2 GB
EGAF50000309772 fastq.gz 632.0 MB
EGAF50000309773 fastq.gz 734.4 MB
EGAF50000309774 fastq.gz 2.2 GB
EGAF50000309775 fastq.gz 844.4 MB
EGAF50000309776 fastq.gz 908.9 MB
EGAF50000309777 fastq.gz 2.8 GB
EGAF50000309778 fastq.gz 5.2 GB
EGAF50000309779 fastq.gz 1.8 GB
EGAF50000309780 fastq.gz 493.5 MB
EGAF50000309781 fastq.gz 584.9 MB
EGAF50000309782 fastq.gz 3.3 GB
EGAF50000309783 fastq.gz 446.4 MB
EGAF50000309784 fastq.gz 1.3 GB
EGAF50000309785 fastq.gz 2.7 GB
EGAF50000309786 fastq.gz 399.0 MB
EGAF50000309787 fastq.gz 455.6 MB
EGAF50000309788 fastq.gz 469.3 MB
EGAF50000309789 fastq.gz 1.3 GB
EGAF50000309790 fastq.gz 2.9 GB
EGAF50000309791 fastq.gz 352.4 MB
EGAF50000309792 fastq.gz 416.3 MB
EGAF50000309793 fastq.gz 1.1 GB
EGAF50000309794 fastq.gz 2.4 GB
EGAF50000309795 fastq.gz 1.1 GB
EGAF50000309796 fastq.gz 343.8 MB
EGAF50000309797 fastq.gz 392.1 MB
EGAF50000309798 fastq.gz 2.3 GB
EGAF50000309799 fastq.gz 2.4 GB
EGAF50000309800 fastq.gz 365.0 MB
EGAF50000309801 fastq.gz 411.6 MB
EGAF50000309802 fastq.gz 1.1 GB
EGAF50000309803 fastq.gz 374.7 MB
EGAF50000309804 fastq.gz 410.9 MB
EGAF50000309805 fastq.gz 1.2 GB
EGAF50000309806 fastq.gz 2.5 GB
EGAF50000309807 fastq.gz 419.9 MB
EGAF50000309808 fastq.gz 406.4 MB
EGAF50000309809 fastq.gz 2.6 GB
EGAF50000309810 fastq.gz 1.2 GB
EGAF50000309811 fastq.gz 215.1 MB
EGAF50000309812 fastq.gz 693.8 MB
EGAF50000309813 fastq.gz 1.1 GB
EGAF50000309814 fastq.gz 685.4 MB
EGAF50000309815 fastq.gz 660.7 MB
EGAF50000309816 fastq.gz 734.1 MB
EGAF50000309817 fastq.gz 2.1 GB
EGAF50000309818 fastq.gz 4.1 GB
EGAF50000309819 fastq.gz 710.6 MB
EGAF50000309820 fastq.gz 2.0 GB
EGAF50000309821 fastq.gz 3.8 GB
EGAF50000309822 fastq.gz 695.2 MB
EGAF50000309823 fastq.gz 679.8 MB
EGAF50000309824 fastq.gz 4.2 GB
EGAF50000309825 fastq.gz 691.8 MB
EGAF50000309826 fastq.gz 2.2 GB
EGAF50000309827 fastq.gz 636.6 MB
EGAF50000309828 fastq.gz 2.0 GB
EGAF50000309829 fastq.gz 597.7 MB
EGAF50000309830 fastq.gz 4.4 GB
EGAF50000309831 fastq.gz 630.2 MB
EGAF50000309832 fastq.gz 729.9 MB
EGAF50000309833 fastq.gz 2.2 GB
EGAF50000309834 fastq.gz 4.2 GB
EGAF50000309835 fastq.gz 838.2 MB
EGAF50000309836 fastq.gz 901.7 MB
EGAF50000309837 fastq.gz 2.8 GB
EGAF50000309838 fastq.gz 5.2 GB
EGAF50000309839 fastq.gz 3.9 GB
EGAF50000309840 fastq.gz 588.6 MB
EGAF50000309841 fastq.gz 669.7 MB
EGAF50000309842 fastq.gz 2.0 GB
EGAF50000309843 fastq.gz 681.0 MB
EGAF50000309844 fastq.gz 668.4 MB
EGAF50000309845 fastq.gz 2.1 GB
EGAF50000309846 fastq.gz 4.1 GB
EGAF50000309847 fastq.gz 373.4 MB
EGAF50000309848 fastq.gz 407.5 MB
EGAF50000309849 fastq.gz 1.2 GB
EGAF50000309850 fastq.gz 2.7 GB
EGAF50000309851 fastq.gz 579.0 MB
EGAF50000309852 fastq.gz 684.5 MB
EGAF50000309853 fastq.gz 1.9 GB
EGAF50000309854 fastq.gz 3.7 GB
EGAF50000309855 fastq.gz 720.9 MB
EGAF50000309856 fastq.gz 808.2 MB
EGAF50000309857 fastq.gz 2.3 GB
EGAF50000309858 fastq.gz 4.5 GB
EGAF50000309859 fastq.gz 2.5 GB
EGAF50000309860 fastq.gz 4.6 GB
EGAF50000309861 fastq.gz 823.7 MB
EGAF50000309862 fastq.gz 778.2 MB
EGAF50000309863 fastq.gz 688.7 MB
EGAF50000309864 fastq.gz 692.4 MB
EGAF50000309865 fastq.gz 2.2 GB
EGAF50000309866 fastq.gz 4.5 GB
EGAF50000309867 fastq.gz 574.3 MB
EGAF50000309868 fastq.gz 1.9 GB
EGAF50000309869 fastq.gz 541.9 MB
EGAF50000309870 fastq.gz 3.9 GB
EGAF50000309871 fastq.gz 549.1 MB
EGAF50000309872 fastq.gz 581.7 MB
EGAF50000309873 fastq.gz 1.8 GB
EGAF50000309874 fastq.gz 4.0 GB
EGAF50000309875 fastq.gz 694.5 MB
EGAF50000309876 fastq.gz 723.3 MB
EGAF50000309877 fastq.gz 2.3 GB
EGAF50000309878 fastq.gz 4.8 GB
EGAF50000309879 fastq.gz 578.6 MB
EGAF50000309880 fastq.gz 553.8 MB
EGAF50000309881 fastq.gz 1.8 GB
EGAF50000309882 fastq.gz 3.9 GB
EGAF50000309883 fastq.gz 533.9 MB
EGAF50000309884 fastq.gz 460.0 MB
EGAF50000309885 fastq.gz 1.4 GB
EGAF50000309886 fastq.gz 2.9 GB
EGAF50000309887 fastq.gz 539.2 MB
EGAF50000309888 fastq.gz 568.0 MB
EGAF50000309889 fastq.gz 1.7 GB
EGAF50000309890 fastq.gz 3.5 GB
EGAF50000309891 fastq.gz 1.1 GB
EGAF50000309892 fastq.gz 333.9 MB
EGAF50000309893 fastq.gz 339.8 MB
EGAF50000309894 fastq.gz 2.3 GB
EGAF50000309895 fastq.gz 813.9 MB
EGAF50000309896 fastq.gz 300.8 MB
EGAF50000309897 fastq.gz 1.8 GB
EGAF50000309898 fastq.gz 264.4 MB
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518 Files (812.3 GB)