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NGS sequencing data of archival FFPE tumor tissue

The aim of the study was to identify mutations in key ovarian cancer genes (BRCA1, BRCA2,TP53, PTEN, ATM, ATR, NF1) in archival fresh-frozen paraffin embedded (FFPE) tumor tissue from platinum-resistant ovarian cancer patients enrolled in the phase I/II GANNET53 clinical trial. From the enrolled 133 patients, archival FFPE tissue was available and DNA was extracted thereof. The DNA samples passing quality control (n=118) were NGS sequenced using the SureSeq™ Ovarian Cancer Panel and the NGS Library Preparation kit (Oxford Gene Technology), which covers all exons of 7 key ovarian cancer genes for single nucleotide variants (SNV) and indels, and the Illumina MiSeq platform. For the paired-end runs, one Read 1 (R1) and one Read 2 (R2) FASTQ file were created for each sample. FASTQ files were compressed and created with the extension \.fastq.gz.

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000935 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF50000330825 fastq.gz 299.0 MB
EGAF50000330826 fastq.gz 315.5 MB
EGAF50000330827 fastq.gz 241.3 MB
EGAF50000330828 fastq.gz 256.3 MB
EGAF50000330829 fastq.gz 143.6 MB
EGAF50000330830 fastq.gz 149.3 MB
EGAF50000330831 fastq.gz 210.0 MB
EGAF50000330832 fastq.gz 164.6 MB
EGAF50000330833 fastq.gz 225.0 MB
EGAF50000330834 fastq.gz 170.1 MB
EGAF50000330835 fastq.gz 229.4 MB
EGAF50000330836 fastq.gz 212.4 MB
EGAF50000330837 fastq.gz 113.1 MB
EGAF50000330838 fastq.gz 122.0 MB
EGAF50000330839 fastq.gz 189.4 MB
EGAF50000330840 fastq.gz 211.2 MB
EGAF50000330841 fastq.gz 502.9 MB
EGAF50000330842 fastq.gz 146.1 MB
EGAF50000330843 fastq.gz 157.4 MB
EGAF50000330844 fastq.gz 554.1 MB
EGAF50000330845 fastq.gz 273.8 MB
EGAF50000330846 fastq.gz 233.8 MB
EGAF50000330847 fastq.gz 291.8 MB
EGAF50000330848 fastq.gz 247.8 MB
EGAF50000330849 fastq.gz 217.9 MB
EGAF50000330850 fastq.gz 88.8 MB
EGAF50000330851 fastq.gz 228.7 MB
EGAF50000330852 fastq.gz 90.9 MB
EGAF50000330853 fastq.gz 138.2 MB
EGAF50000330854 fastq.gz 145.3 MB
EGAF50000330855 fastq.gz 217.9 MB
EGAF50000330856 fastq.gz 119.2 MB
EGAF50000330857 fastq.gz 122.5 MB
EGAF50000330858 fastq.gz 235.4 MB
EGAF50000330859 fastq.gz 145.3 MB
EGAF50000330860 fastq.gz 117.3 MB
EGAF50000330861 fastq.gz 153.4 MB
EGAF50000330862 fastq.gz 120.9 MB
EGAF50000330863 fastq.gz 96.0 MB
EGAF50000330864 fastq.gz 100.8 MB
EGAF50000330865 fastq.gz 119.5 MB
EGAF50000330866 fastq.gz 125.0 MB
EGAF50000330867 fastq.gz 160.7 MB
EGAF50000330868 fastq.gz 101.8 MB
EGAF50000330869 fastq.gz 169.3 MB
EGAF50000330870 fastq.gz 136.5 MB
EGAF50000330871 fastq.gz 105.4 MB
EGAF50000330872 fastq.gz 149.0 MB
EGAF50000330873 fastq.gz 147.0 MB
EGAF50000330874 fastq.gz 142.7 MB
EGAF50000330875 fastq.gz 94.0 MB
EGAF50000330876 fastq.gz 96.7 MB
EGAF50000330877 fastq.gz 136.2 MB
EGAF50000330878 fastq.gz 141.6 MB
EGAF50000330879 fastq.gz 186.0 MB
EGAF50000330880 fastq.gz 148.9 MB
EGAF50000330881 fastq.gz 193.1 MB
EGAF50000330882 fastq.gz 153.7 MB
EGAF50000330883 fastq.gz 150.5 MB
EGAF50000330884 fastq.gz 158.0 MB
EGAF50000330885 fastq.gz 251.5 MB
EGAF50000330886 fastq.gz 235.3 MB
EGAF50000330887 fastq.gz 167.2 MB
EGAF50000330888 fastq.gz 182.2 MB
EGAF50000330889 fastq.gz 262.5 MB
EGAF50000330890 fastq.gz 279.7 MB
EGAF50000330891 fastq.gz 253.0 MB
EGAF50000330892 fastq.gz 176.8 MB
EGAF50000330893 fastq.gz 265.8 MB
EGAF50000330894 fastq.gz 130.8 MB
EGAF50000330895 fastq.gz 188.2 MB
EGAF50000330896 fastq.gz 140.1 MB
EGAF50000330897 fastq.gz 181.9 MB
EGAF50000330898 fastq.gz 193.5 MB
EGAF50000330899 fastq.gz 191.5 MB
EGAF50000330900 fastq.gz 117.2 MB
EGAF50000330901 fastq.gz 197.8 MB
EGAF50000330902 fastq.gz 120.8 MB
EGAF50000330903 fastq.gz 99.0 MB
EGAF50000330904 fastq.gz 147.4 MB
EGAF50000330905 fastq.gz 104.4 MB
EGAF50000330906 fastq.gz 126.8 MB
EGAF50000330907 fastq.gz 155.0 MB
EGAF50000330908 fastq.gz 134.8 MB
EGAF50000330909 fastq.gz 149.1 MB
EGAF50000330910 fastq.gz 158.4 MB
EGAF50000330911 fastq.gz 161.4 MB
EGAF50000330912 fastq.gz 130.4 MB
EGAF50000330913 fastq.gz 170.9 MB
EGAF50000330914 fastq.gz 141.8 MB
EGAF50000330915 fastq.gz 139.9 MB
EGAF50000330916 fastq.gz 148.2 MB
EGAF50000330917 fastq.gz 139.9 MB
EGAF50000330918 fastq.gz 145.0 MB
EGAF50000330919 fastq.gz 269.5 MB
EGAF50000330920 fastq.gz 284.8 MB
EGAF50000330921 fastq.gz 106.2 MB
EGAF50000330922 fastq.gz 113.3 MB
EGAF50000330923 fastq.gz 160.2 MB
EGAF50000330924 fastq.gz 174.0 MB
EGAF50000330925 fastq.gz 169.1 MB
EGAF50000330926 fastq.gz 158.5 MB
EGAF50000330927 fastq.gz 195.4 MB
EGAF50000330928 fastq.gz 207.7 MB
EGAF50000330929 fastq.gz 165.0 MB
EGAF50000330930 fastq.gz 111.2 MB
EGAF50000330931 fastq.gz 171.7 MB
EGAF50000330932 fastq.gz 176.9 MB
EGAF50000330933 fastq.gz 246.6 MB
EGAF50000330934 fastq.gz 273.0 MB
EGAF50000330935 fastq.gz 207.8 MB
EGAF50000330936 fastq.gz 220.9 MB
EGAF50000330937 fastq.gz 133.0 MB
EGAF50000330938 fastq.gz 138.5 MB
EGAF50000330939 fastq.gz 179.4 MB
EGAF50000330940 fastq.gz 166.1 MB
EGAF50000330941 fastq.gz 216.6 MB
EGAF50000330942 fastq.gz 161.5 MB
EGAF50000330943 fastq.gz 227.6 MB
EGAF50000330944 fastq.gz 173.7 MB
EGAF50000330945 fastq.gz 149.1 MB
EGAF50000330946 fastq (1).gz 173.8 MB
EGAF50000330947 fastq.gz 168.0 MB
EGAF50000330948 fastq.gz 185.3 MB
EGAF50000330949 fastq.gz 144.1 MB
EGAF50000330950 fastq.gz 149.9 MB
EGAF50000330951 fastq.gz 201.8 MB
EGAF50000330952 fastq.gz 219.5 MB
EGAF50000330953 fastq.gz 137.0 MB
EGAF50000330954 fastq.gz 147.0 MB
EGAF50000330955 fastq.gz 177.4 MB
EGAF50000330956 fastq.gz 183.7 MB
EGAF50000330957 fastq.gz 114.3 MB
EGAF50000330958 fastq.gz 122.8 MB
EGAF50000330959 fastq.gz 128.2 MB
EGAF50000330960 fastq.gz 138.5 MB
EGAF50000330961 fastq.gz 272.0 MB
EGAF50000330962 fastq.gz 287.0 MB
EGAF50000330963 fastq.gz 116.5 MB
EGAF50000330964 fastq.gz 125.9 MB
EGAF50000330965 fastq.gz 102.1 MB
EGAF50000330966 fastq.gz 105.6 MB
EGAF50000330967 fastq.gz 113.9 MB
EGAF50000330968 fastq.gz 111.1 MB
EGAF50000330969 fastq.gz 165.2 MB
EGAF50000330970 fastq.gz 169.0 MB
EGAF50000330971 fastq.gz 178.2 MB
EGAF50000330972 fastq.gz 163.3 MB
EGAF50000330973 fastq.gz 609.0 MB
EGAF50000330974 fastq.gz 645.2 MB
EGAF50000330975 fastq.gz 109.1 MB
EGAF50000330976 fastq.gz 105.9 MB
EGAF50000330977 fastq.gz 203.3 MB
EGAF50000330978 fastq.gz 190.4 MB
EGAF50000330979 fastq.gz 120.8 MB
EGAF50000330980 fastq.gz 130.2 MB
EGAF50000330981 fastq.gz 114.5 MB
EGAF50000330982 fastq.gz 123.1 MB
EGAF50000330983 fastq.gz 140.1 MB
EGAF50000330984 fastq.gz 123.9 MB
EGAF50000330985 fastq.gz 145.3 MB
EGAF50000330986 fastq.gz 139.2 MB
EGAF50000330987 fastq.gz 123.0 MB
EGAF50000330988 fastq.gz 116.2 MB
EGAF50000330989 fastq.gz 186.7 MB
EGAF50000330990 fastq.gz 142.1 MB
EGAF50000330991 fastq.gz 100.6 MB
EGAF50000330992 fastq.gz 97.1 MB
EGAF50000330993 fastq.gz 125.1 MB
EGAF50000330994 fastq.gz 132.0 MB
EGAF50000330995 fastq.gz 170.0 MB
EGAF50000330996 fastq.gz 160.6 MB
EGAF50000330997 fastq.gz 267.5 MB
EGAF50000330998 fastq.gz 251.3 MB
EGAF50000330999 fastq.gz 211.6 MB
EGAF50000331000 fastq.gz 223.6 MB
EGAF50000331001 fastq.gz 248.2 MB
EGAF50000331002 fastq.gz 232.4 MB
EGAF50000331003 fastq.gz 235.0 MB
EGAF50000331004 fastq.gz 220.1 MB
EGAF50000331005 fastq.gz 215.5 MB
EGAF50000331006 fastq.gz 203.0 MB
EGAF50000331007 fastq.gz 161.3 MB
EGAF50000331008 fastq.gz 146.0 MB
EGAF50000331009 fastq.gz 234.5 MB
EGAF50000331010 fastq.gz 119.2 MB
EGAF50000331011 fastq.gz 223.4 MB
EGAF50000331012 fastq.gz 113.4 MB
EGAF50000331013 fastq.gz 243.7 MB
EGAF50000331014 fastq.gz 234.7 MB
EGAF50000331015 fastq.gz 148.8 MB
EGAF50000331016 fastq.gz 88.4 MB
EGAF50000331017 fastq.gz 137.4 MB
EGAF50000331018 fastq.gz 86.0 MB
EGAF50000331019 fastq.gz 167.1 MB
EGAF50000331020 fastq.gz 158.7 MB
EGAF50000331021 fastq.gz 160.7 MB
EGAF50000331022 fastq.gz 149.1 MB
EGAF50000331023 fastq.gz 151.3 MB
EGAF50000331024 fastq.gz 159.7 MB
EGAF50000331025 fastq.gz 216.3 MB
EGAF50000331026 fastq.gz 199.4 MB
EGAF50000331027 fastq.gz 172.8 MB
EGAF50000331028 fastq.gz 164.4 MB
EGAF50000331029 fastq.gz 163.9 MB
EGAF50000331030 fastq.gz 156.2 MB
EGAF50000331031 fastq.gz 202.7 MB
EGAF50000331032 fastq.gz 190.1 MB
EGAF50000331033 fastq.gz 278.0 MB
EGAF50000331034 fastq.gz 260.9 MB
EGAF50000331035 fastq.gz 139.0 MB
EGAF50000331036 fastq.gz 125.9 MB
EGAF50000331037 fastq.gz 183.9 MB
EGAF50000331038 fastq.gz 172.3 MB
EGAF50000331039 fastq.gz 145.3 MB
EGAF50000331040 fastq.gz 139.8 MB
EGAF50000331041 fastq.gz 220.9 MB
EGAF50000331042 fastq.gz 211.1 MB
EGAF50000331043 fastq.gz 130.6 MB
EGAF50000331044 fastq.gz 126.4 MB
EGAF50000331045 fastq.gz 136.4 MB
EGAF50000331046 fastq.gz 125.2 MB
EGAF50000331047 fastq.gz 312.6 MB
EGAF50000331048 fastq.gz 295.0 MB
EGAF50000331049 fastq.gz 127.6 MB
EGAF50000331050 fastq.gz 118.4 MB
EGAF50000331051 fastq.gz 146.9 MB
EGAF50000331052 fastq.gz 140.4 MB
EGAF50000331053 fastq.gz 548.9 MB
EGAF50000331054 fastq.gz 506.7 MB
EGAF50000331055 fastq.gz 150.8 MB
EGAF50000331056 fastq.gz 145.0 MB
EGAF50000331057 fastq.gz 123.7 MB
EGAF50000331058 fastq.gz 115.9 MB
EGAF50000331059 fastq.gz 256.9 MB
EGAF50000331060 fastq.gz 238.0 MB
236 Files (42.4 GB)