10x single-nucleus RNA-seq of postoperative human FCD II brain tissues
This dataset contains 10x Genomics single-nucleus RNA sequencing data from postoperative brain tissues of patients with focal cortical dysplasia type II (FCD II). The samples were processed using the Chromium platform.
- 18/06/2025
- 10 samples
- DAC: EGAC50000000546
- Technologies: Illumina HiSeq 2500, Illumina NovaSeq 6000
DUO:0000018 version: 2021-02-23
not for profit, non commercial use only
This data use modifier indicates that use of the data is limited to not-for-profit organizations and not-for-profit use, non-commercial use.
DUO:0000026 version: 2021-02-23
user specific restriction
This data use modifier indicates that use is limited to use by approved users.
DUO:0000027 version: 2021-02-23
project specific restriction
This data use modifier indicates that use is limited to use within an approved project.
DUO:0000028 version: 2021-02-23
institution specific restriction
This data use modifier indicates that use is limited to use within an approved institution.
Data Access Policy for Human Brain Genomic Studies
1. Purpose of the Policy This data access policy governs the controlled sharing of single-nucleus RNA sequencing (snRNA-seq) data obtained from postoperative human brain tissue of patients with drug-resistant epilepsy. The policy ensures compliance with ethical and legal requirements while facilitating responsible data sharing for scientific research. 2. Consent and Confidentiality The dataset contains pseudonymized single-nuclei transcriptomic data. Patients provided informed consent for the use of their data in research. No direct personal identifiers are included in the dataset. Any attempt to cross-reference the data with other sources to re-identify individuals is strictly prohibited. 3. Data Access Requirements Access to the dataset is controlled and requires approval from the Data Access Committee (DAC). Data requests must come from recognized academic, clinical, or non-profit research institutions. Applicants must provide a detailed research proposal specifying the intended use of the data. Data will not be shared for commercial purposes. 4. Data Use Agreement (DUA) Access to the dataset is strictly conditional upon prior signature of a Data Use Agreement (DUA) specifying the rights and obligations of data users, including compliance with ethical and legal requirements. The dataset must not be shared with third parties without prior authorization. Users must ensure that data security measures are in place to prevent unauthorized access. 5. Governance and Oversight A designated Data Access Committee (DAC) will review and approve data access requests. The DAC will ensure that research proposals align with the original ethical approvals. Approved researchers must report any publications or findings arising from the dataset. 6. Restrictions Data use is restricted to non-commercial scientific research. Any results generated must adhere to Open Science principles, where applicable. Researchers must comply with local and international data protection regulations.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000000964 | Transcriptome Sequencing |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
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| EGAF50000350200 | fastq.gz | 1.1 GB |
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| EGAF50000350201 | fastq.gz | 3.7 GB |
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| EGAF50000350202 | fastq.gz | 8.6 GB |
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| EGAF50000350203 | fastq.gz | 827.0 MB |
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| EGAF50000350204 | fastq.gz | 2.8 GB |
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| EGAF50000350205 | fastq.gz | 6.5 GB |
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| EGAF50000350206 | fastq.gz | 23.1 GB |
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| EGAF50000350207 | fastq.gz | 2.6 GB |
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| EGAF50000350208 | fastq.gz | 7.9 GB |
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| EGAF50000350209 | fastq.gz | 13.0 GB |
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| EGAF50000350210 | fastq.gz | 28.8 GB |
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| EGAF50000350211 | fastq.gz | 3.7 GB |
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| EGAF50000350212 | fastq.gz | 8.5 GB |
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| EGAF50000350213 | fastq.gz | 1.1 GB |
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| EGAF50000350214 | fastq.gz | 55.3 GB |
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| EGAF50000350215 | fastq.gz | 131.7 GB |
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| EGAF50000350216 | fastq.gz | 642.7 MB |
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| EGAF50000350217 | fastq.gz | 2.2 GB |
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| EGAF50000350218 | fastq.gz | 5.0 GB |
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| EGAF50000350219 | fastq.gz | 652.3 MB |
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| EGAF50000350220 | fastq.gz | 2.2 GB |
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| EGAF50000350221 | fastq.gz | 5.1 GB |
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| EGAF50000350222 | fastq.gz | 11.0 GB |
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| EGAF50000350223 | fastq.gz | 24.3 GB |
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| EGAF50000350224 | fastq.gz | 2.9 GB |
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| EGAF50000350225 | fastq.gz | 837.4 MB |
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| EGAF50000350226 | fastq.gz | 6.6 GB |
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| EGAF50000350227 | fastq.gz | 28.4 GB |
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| EGAF50000350228 | fastq.gz | 13.0 GB |
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| EGAF50000350229 | fastq.gz | 14.7 GB |
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| EGAF50000350230 | fastq.gz | 32.6 GB |
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| EGAF50000350231 | fastq.gz | 7.8 GB |
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| EGAF50000350232 | fastq.gz | 2.6 GB |
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| EGAF50000350233 | fastq.gz | 22.8 GB |
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| EGAF50000350234 | fastq.gz | 139.7 GB |
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| EGAF50000350235 | fastq.gz | 58.9 GB |
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| 36 Files (681.3 GB) | ||||
