About file location

As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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Human Single-Oocyte Transcriptome - Control and Cannabis Treated

RNAseq data of human single oocytes exposed to THC and its metabolites, (mean concentration measured in the follicular fluid, THC1, n=95, 25 ng/mL Δ9-THC, 5 ng/mL 11-OH-THC, 50 ng/mL 11-COOH-THC) or a supraphysiologic, THC2, n=93, 100 ng/mL Δ9-THC, 50 ng/mL 11-OH-THC, 200 ng/mL 11-COOH-THC).

Request Access

DUO:0000021
version: 2021-02-23

ethics approval required

This data use modifier indicates that the requestor must provide documentation of local IRB/ERB approval.

DUO:0000026
version: 2021-02-23

user specific restriction

This data use modifier indicates that use is limited to use by approved users.

DUO:0000027
version: 2021-02-23

project specific restriction

This data use modifier indicates that use is limited to use within an approved project.

DATA ACCESS AGREEMENT – CReATe Fertility Centre

DATA ACCESS AGREEMENT – CReATe Fertility Centre These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom CReATe Fertility Centre grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorized Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. DAC: Data access committee. Data Producers: CReATe Fertility Centre employees and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. DAC Institution: CReATe Fertility Centre. With an address at: 790 Bay Street, Toronto, ON M5G 1N8 Contact information: Dr. Clifford Librach T: 416-323-7727(drlibrach@createivf.com) and other CReATe Fertility Centre invited to be DAC members. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorized Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognizing the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analyzing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify CReATe Fertility Centre DAC within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify CReATe Fertility Centre DAC prior to any significant changes to the protocol for the Project. 14. The User Institution will notify CReATe Fertility Centre DAC as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. CReATe Fertility Centre may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement at any time. As an example, this may include specific provisions relating to the Data required by Data Producers other than CReATe Fertility Centre. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. User Institution personnel shall use appropriate safeguards (including without limitation with respect to encrypting identifying numbers, linking files, storing and retrieving files from secured locations) to prevent any unauthorized use or disclosure of the Data and shall promptly report to CReATe Fertility Centre DAC any unauthorized use or disclosure of which Recipient becomes aware. 20. All results, data, experiences and inventions generated by User Institution personnel in connection with its use of the Data shall be available to CReATe Fertility Centre at all times. User Institution personnel shall fully cooperate with CReATe Fertility Centre, at User Institution personnel's cost, providing such documents and information and performing such acts as are reasonably requested by CReATe Fertility Centre. Ownership of intellectual property invented or created under this Agreement shall lie with CReATe Fertility Centre. Agreed for User Institution Signature: Name: Title: Date: Principal Investigator I confirm that I have read and understood this Agreement. Signature: Name: Title: Date: Agreed for CReaTe Fertility Centre Signature: Name: Title: Date: APPENDIX I – DATASET DETAILS APPENDIX II ––PROJECT DETAILS APPENDIX III –– PUBLICATION POLICY APPENDIX I – DATASET DETAILS (to be completed by the data producer before passing to applicant) Dataset reference (EGA Study ID and Dataset Details) Name of project that created the dataset Names of other data producers/collaborators Specific limitations on areas of research Minimum protection measures required File access: Data can be held in unencrypted files on an institutional computer system, with Unix user group read/write access for one or more appropriate groups but not Unix world read/write access behind a secure firewall. Laptops holding these data should have password protected logins and screenlocks (set to lock after 5 min of inactivity). If held on USB keys or other portable hard drives, the data must be encrypted. APPENDIX II – PROJECT DETAILS (to be completed by the Requestor) Details of dataset requested i.e., EGA Study and Dataset Accession Number Brief abstract of the Project in which the Data will be used (500 words max) All Individuals who the User Institution to be named as registered users Name of Registered User Email Job Title Supervisor* All Individuals that should have an account created at the EGA Name of Registered User Email Job Title APPENDIX III – PUBLICATION POLICY CReATe Fertility Centre intends to publish the results of their analysis of this dataset and do not consider its deposition into public databases to be the equivalent of such publications. CReATe Fertility Centre anticipates that the dataset could be useful to other qualified researchers for a variety of purposes. However, some areas of work are subject to a publication moratorium. The publication moratorium covers any publications (including oral and poster communications) that describe the use of the dataset. For research papers, submission for publication should not occur until 12 months after these data were first made available on the relevant hosting database, unless CReATe Fertility Centre has provided written consent to earlier submission. In any publications based on these data, please describe how the data can be accessed, including the name of the hosting database (e.g., The European Genome-phenome Archive at the European Bioinformatics Institute) and its accession numbers (e.g., EGAS00000000029), and acknowledge its use in a form agreed by the User Institution with CReATe Fertility Centre.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000001052 Transcriptome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF50000382068 fastq.gz 1.1 GB
EGAF50000382069 fastq.gz 1.2 GB
EGAF50000382070 fastq.gz 1.2 GB
EGAF50000382071 fastq.gz 1.2 GB
EGAF50000382072 fastq.gz 1.2 GB
EGAF50000382073 fastq.gz 1.2 GB
EGAF50000382074 fastq.gz 1.4 GB
EGAF50000382075 fastq.gz 1.5 GB
EGAF50000382076 fastq.gz 1.5 GB
EGAF50000382077 fastq.gz 1.6 GB
EGAF50000382078 fastq.gz 1.0 GB
EGAF50000382079 fastq.gz 1.1 GB
EGAF50000382080 fastq.gz 1.2 GB
EGAF50000382081 fastq.gz 1.1 GB
EGAF50000382082 fastq.gz 996.0 MB
EGAF50000382083 fastq.gz 1.1 GB
EGAF50000382084 fastq.gz 1.3 GB
EGAF50000382085 fastq.gz 1.4 GB
EGAF50000382086 fastq.gz 1.3 GB
EGAF50000382087 fastq.gz 1.3 GB
EGAF50000382088 fastq.gz 1.6 GB
EGAF50000382089 fastq.gz 1.7 GB
EGAF50000382090 fastq.gz 1.6 GB
EGAF50000382091 fastq.gz 1.7 GB
EGAF50000382092 fastq.gz 1.3 GB
EGAF50000382093 fastq.gz 1.3 GB
EGAF50000382094 fastq.gz 1.1 GB
EGAF50000382095 fastq.gz 1.0 GB
EGAF50000382096 fastq.gz 1.3 GB
EGAF50000382097 fastq.gz 1.2 GB
EGAF50000382098 fastq.gz 1.0 GB
EGAF50000382099 fastq.gz 994.6 MB
EGAF50000382100 fastq.gz 1.4 GB
EGAF50000382101 fastq.gz 1.4 GB
EGAF50000382102 fastq.gz 1.4 GB
EGAF50000382103 fastq.gz 1.4 GB
EGAF50000382104 fastq.gz 1.4 GB
EGAF50000382105 fastq.gz 1.4 GB
EGAF50000382106 fastq.gz 1.4 GB
EGAF50000382107 fastq.gz 1.3 GB
EGAF50000382108 fastq.gz 2.2 GB
EGAF50000382109 fastq.gz 2.3 GB
EGAF50000382110 fastq.gz 1.1 GB
EGAF50000382111 fastq.gz 1.0 GB
EGAF50000382112 fastq.gz 2.2 GB
EGAF50000382113 fastq.gz 2.2 GB
EGAF50000382114 fastq.gz 1.0 GB
EGAF50000382115 fastq.gz 1.1 GB
EGAF50000382116 fastq.gz 1.4 GB
EGAF50000382117 fastq.gz 1.3 GB
EGAF50000382118 fastq.gz 1.3 GB
EGAF50000382119 fastq.gz 870.5 MB
EGAF50000382120 fastq.gz 1.3 GB
EGAF50000382121 fastq.gz 837.8 MB
EGAF50000382122 fastq.gz 849.1 MB
EGAF50000382123 fastq.gz 818.5 MB
EGAF50000382124 fastq.gz 1.2 GB
EGAF50000382125 fastq.gz 1.2 GB
EGAF50000382126 fastq.gz 1.1 GB
EGAF50000382127 fastq.gz 1.2 GB
EGAF50000382128 fastq.gz 2.2 GB
EGAF50000382129 fastq.gz 2.3 GB
EGAF50000382130 fastq.gz 2.1 GB
EGAF50000382131 fastq.gz 2.0 GB
EGAF50000382132 fastq.gz 2.5 GB
EGAF50000382133 fastq.gz 1.9 GB
EGAF50000382134 fastq.gz 2.4 GB
EGAF50000382135 fastq.gz 2.0 GB
EGAF50000382136 fastq.gz 1.8 GB
EGAF50000382137 fastq.gz 1.7 GB
EGAF50000382138 fastq.gz 1.7 GB
EGAF50000382139 fastq.gz 1.6 GB
EGAF50000382140 fastq.gz 2.2 GB
EGAF50000382141 fastq.gz 2.2 GB
EGAF50000382142 fastq.gz 2.8 GB
EGAF50000382143 fastq.gz 2.7 GB
EGAF50000382144 fastq.gz 2.4 GB
EGAF50000382145 fastq.gz 2.3 GB
EGAF50000382146 fastq.gz 4.1 GB
EGAF50000382147 fastq.gz 3.9 GB
EGAF50000382148 fastq.gz 2.4 GB
EGAF50000382149 fastq.gz 2.3 GB
EGAF50000382150 fastq.gz 4.3 GB
EGAF50000382151 fastq.gz 4.2 GB
EGAF50000382152 fastq.gz 1.7 GB
EGAF50000382153 fastq.gz 1.7 GB
EGAF50000382154 fastq.gz 1.9 GB
EGAF50000382155 fastq.gz 2.0 GB
EGAF50000382156 fastq.gz 3.2 GB
EGAF50000382157 fastq.gz 3.2 GB
EGAF50000382158 fastq.gz 3.2 GB
EGAF50000382159 fastq.gz 3.3 GB
EGAF50000382160 fastq.gz 2.9 GB
EGAF50000382161 fastq.gz 2.8 GB
EGAF50000382162 fastq.gz 2.2 GB
EGAF50000382163 fastq.gz 2.1 GB
EGAF50000382164 fastq.gz 2.4 GB
EGAF50000382165 fastq.gz 2.4 GB
EGAF50000382166 fastq.gz 2.7 GB
EGAF50000382167 fastq.gz 2.8 GB
EGAF50000382168 fastq.gz 2.2 GB
EGAF50000382169 fastq.gz 2.2 GB
EGAF50000382170 fastq.gz 4.7 GB
EGAF50000382171 fastq.gz 3.0 GB
EGAF50000382172 fastq.gz 3.2 GB
EGAF50000382173 fastq.gz 4.9 GB
EGAF50000382174 fastq.gz 1.6 GB
EGAF50000382175 fastq.gz 1.6 GB
EGAF50000382176 fastq.gz 1.6 GB
EGAF50000382177 fastq.gz 1.6 GB
EGAF50000382178 fastq.gz 2.6 GB
EGAF50000382179 fastq.gz 2.7 GB
EGAF50000382180 fastq.gz 3.8 GB
EGAF50000382181 fastq.gz 3.9 GB
EGAF50000382182 fastq.gz 2.3 GB
EGAF50000382183 fastq.gz 2.2 GB
EGAF50000382184 fastq.gz 1.9 GB
EGAF50000382185 fastq.gz 1.8 GB
EGAF50000382186 fastq.gz 2.0 GB
EGAF50000382187 fastq.gz 2.0 GB
EGAF50000382188 fastq.gz 1.9 GB
EGAF50000382189 fastq.gz 1.8 GB
EGAF50000382190 fastq.gz 2.0 GB
EGAF50000382191 fastq.gz 1.9 GB
EGAF50000382192 fastq.gz 2.0 GB
EGAF50000382193 fastq.gz 1.9 GB
EGAF50000382194 fastq.gz 2.1 GB
EGAF50000382195 fastq.gz 2.1 GB
EGAF50000382196 fastq.gz 2.2 GB
EGAF50000382197 fastq.gz 2.1 GB
EGAF50000382198 fastq.gz 3.6 GB
EGAF50000382199 fastq.gz 3.5 GB
EGAF50000382200 fastq.gz 2.3 GB
EGAF50000382201 fastq.gz 2.4 GB
EGAF50000382202 fastq.gz 1.9 GB
EGAF50000382203 fastq.gz 1.9 GB
EGAF50000382204 fastq.gz 2.2 GB
EGAF50000382205 fastq.gz 2.1 GB
EGAF50000382206 fastq.gz 1.6 GB
EGAF50000382207 fastq.gz 1.6 GB
EGAF50000382208 fastq.gz 1.6 GB
EGAF50000382209 fastq.gz 1.5 GB
EGAF50000382210 fastq.gz 1.2 GB
EGAF50000382211 fastq.gz 1.1 GB
EGAF50000382212 fastq.gz 2.0 GB
EGAF50000382213 fastq.gz 1.9 GB
EGAF50000382214 fastq.gz 1.2 GB
EGAF50000382215 fastq.gz 1.1 GB
EGAF50000382216 fastq.gz 1.7 GB
EGAF50000382217 fastq.gz 1.6 GB
EGAF50000382218 fastq.gz 2.4 GB
EGAF50000382219 fastq.gz 2.5 GB
EGAF50000382220 fastq.gz 1.7 GB
EGAF50000382221 fastq.gz 2.6 GB
EGAF50000382222 fastq.gz 2.5 GB
EGAF50000382223 fastq.gz 1.7 GB
EGAF50000382224 fastq.gz 2.7 GB
EGAF50000382225 fastq.gz 2.7 GB
EGAF50000382226 fastq.gz 3.1 GB
EGAF50000382227 fastq.gz 3.3 GB
EGAF50000382228 fastq.gz 1.7 GB
EGAF50000382229 fastq.gz 1.6 GB
EGAF50000382230 fastq.gz 2.4 GB
EGAF50000382231 fastq.gz 2.3 GB
EGAF50000382232 fastq.gz 1.6 GB
EGAF50000382233 fastq.gz 1.6 GB
EGAF50000382234 fastq.gz 1.6 GB
EGAF50000382235 fastq.gz 1.6 GB
EGAF50000382236 fastq.gz 1.9 GB
EGAF50000382237 fastq.gz 1.7 GB
EGAF50000382238 fastq.gz 3.2 GB
EGAF50000382239 fastq.gz 3.2 GB
EGAF50000382240 fastq.gz 1.6 GB
EGAF50000382241 fastq.gz 1.8 GB
EGAF50000382242 fastq.gz 1.7 GB
EGAF50000382243 fastq.gz 1.8 GB
EGAF50000382244 fastq.gz 2.6 GB
EGAF50000382245 fastq.gz 2.0 GB
EGAF50000382246 fastq.gz 2.8 GB
EGAF50000382247 fastq.gz 2.1 GB
EGAF50000382248 fastq.gz 1.9 GB
EGAF50000382249 fastq.gz 1.9 GB
EGAF50000382250 fastq.gz 2.4 GB
EGAF50000382251 fastq.gz 2.3 GB
EGAF50000382252 fastq.gz 1.8 GB
EGAF50000382253 fastq.gz 1.7 GB
EGAF50000382254 fastq.gz 2.1 GB
EGAF50000382255 fastq.gz 2.3 GB
EGAF50000382256 fastq.gz 2.2 GB
EGAF50000382257 fastq.gz 2.3 GB
EGAF50000382258 fastq.gz 2.0 GB
EGAF50000382259 fastq.gz 2.0 GB
EGAF50000382260 fastq.gz 2.0 GB
EGAF50000382261 fastq.gz 2.1 GB
EGAF50000382262 fastq.gz 2.2 GB
EGAF50000382263 fastq.gz 2.2 GB
EGAF50000382264 fastq.gz 2.8 GB
EGAF50000382265 fastq.gz 2.7 GB
EGAF50000382266 fastq.gz 1.6 GB
EGAF50000382267 fastq.gz 1.6 GB
EGAF50000382268 fastq.gz 2.3 GB
EGAF50000382269 fastq.gz 2.3 GB
202 Files (401.3 GB)