Survival and safety of laser interstitial thermal therapy and adjuvant pembrolizumab in recurrent high-grade astrocytoma: a Phase 1/randomized Phase 2b trial
This dataset is the immune profiling of the trial patients. Cryopreserved PBMCs obtained from the patients at different time points were processed to single-cell transcriptomic or TCR libraries using 10x next GEM single Cell 5' v2 kit. We also performed whole exome sequencing (WES) of the tumor to identify the mutation burden. The WES data was generated by sequencing company Novogene. There are total of 69 of single cell libraires, 69 of single cell TCR libraries, and 13 of tumor WES data being generated from 18 trial patients recruited at University of Florida.
- 30/01/2026
- 82 samples
- DAC: EGAC50000000677
- Technology: Illumina NovaSeq 6000
DUO:0000042 version: 2021-02-23
general research use
This data use permission indicates that use is allowed for general research use for any research purpose.
USC Data Agreement Policy
General Research Use Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000001144 | RNASeq |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
i
|
|---|---|---|---|---|
| EGAF50000404150 | vcf | 35.5 MB |
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| EGAF50000404151 | vcf | 31.9 MB |
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| EGAF50000404152 | vcf | 37.2 MB |
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| EGAF50000404153 | fastq.gz | 7.1 GB |
|
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| EGAF50000404154 | fastq.gz | 4.6 GB |
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| EGAF50000404155 | fastq.gz | 27.7 GB |
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| EGAF50000404156 | fastq.gz | 2.2 GB |
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| EGAF50000404157 | fastq.gz | 7.8 GB |
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| EGAF50000404158 | fastq.gz | 6.9 GB |
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| EGAF50000404159 | fastq.gz | 2.0 GB |
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| EGAF50000404160 | fastq.gz | 8.5 GB |
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| EGAF50000404161 | fastq.gz | 1.4 GB |
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| EGAF50000404162 | fastq.gz | 6.8 GB |
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| EGAF50000404163 | fastq.gz | 27.2 GB |
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| EGAF50000404164 | fastq.gz | 5.3 GB |
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| EGAF50000404165 | fastq.gz | 5.4 GB |
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| EGAF50000404166 | fastq.gz | 21.2 GB |
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| EGAF50000404167 | fastq.gz | 29.5 GB |
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| EGAF50000404168 | fastq.gz | 4.2 GB |
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| EGAF50000404169 | fastq.gz | 2.4 GB |
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| EGAF50000404170 | fastq.gz | 6.7 GB |
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| EGAF50000404171 | fastq.gz | 14.0 GB |
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| EGAF50000404172 | fastq.gz | 6.1 GB |
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| EGAF50000404173 | fastq.gz | 25.5 GB |
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| EGAF50000404174 | fastq.gz | 1.8 GB |
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| EGAF50000404175 | fastq.gz | 23.7 GB |
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| EGAF50000404176 | fastq.gz | 7.5 GB |
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| EGAF50000404177 | fastq.gz | 6.4 GB |
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| EGAF50000404178 | fastq.gz | 2.0 GB |
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| EGAF50000404179 | fastq.gz | 7.6 GB |
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| EGAF50000404180 | fastq.gz | 29.1 GB |
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| EGAF50000404181 | fastq.gz | 55.6 GB |
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| EGAF50000404182 | fastq.gz | 6.9 GB |
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| EGAF50000404183 | fastq.gz | 26.8 GB |
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| EGAF50000404184 | fastq.gz | 1.9 GB |
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| EGAF50000404185 | fastq.gz | 6.7 GB |
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| EGAF50000404186 | fastq.gz | 7.2 GB |
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| EGAF50000404187 | fastq.gz | 1.6 GB |
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| EGAF50000404188 | fastq.gz | 5.6 GB |
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| EGAF50000404189 | fastq.gz | 23.8 GB |
|
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| EGAF50000404190 | fastq.gz | 24.1 GB |
|
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| EGAF50000404191 | fastq.gz | 11.6 GB |
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| EGAF50000404192 | fastq.gz | 2.1 GB |
|
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| EGAF50000404193 | fastq.gz | 7.2 GB |
|
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| EGAF50000404194 | fastq.gz | 27.6 GB |
|
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| EGAF50000404195 | fastq.gz | 29.2 GB |
|
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| EGAF50000404196 | fastq.gz | 7.0 GB |
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| EGAF50000404197 | fastq.gz | 7.7 GB |
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| EGAF50000404198 | fastq.gz | 33.9 GB |
|
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| EGAF50000404199 | fastq.gz | 6.6 GB |
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| EGAF50000404200 | fastq.gz | 25.6 GB |
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| EGAF50000404201 | fastq.gz | 6.2 GB |
|
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| EGAF50000404202 | fastq.gz | 23.4 GB |
|
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| EGAF50000404203 | fastq.gz | 7.7 GB |
|
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| EGAF50000404204 | fastq.gz | 26.8 GB |
|
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| EGAF50000404205 | fq.gz | 3.2 GB |
|
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| EGAF50000404206 | fastq.gz | 1.2 GB |
|
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| EGAF50000404207 | fastq.gz | 4.4 GB |
|
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| EGAF50000404208 | fastq.gz | 2.0 GB |
|
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| EGAF50000404209 | fastq.gz | 7.8 GB |
|
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| EGAF50000404210 | fq.gz | 3.7 GB |
|
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| EGAF50000404211 | fastq.gz | 1.4 GB |
|
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| EGAF50000404212 | fastq.gz | 5.0 GB |
|
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| EGAF50000404213 | fastq.gz | 6.1 GB |
|
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| EGAF50000404214 | fastq.gz | 1.4 GB |
|
|
| EGAF50000404215 | fastq.gz | 5.0 GB |
|
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| EGAF50000404216 | fastq.gz | 1.2 GB |
|
|
| EGAF50000404217 | fastq.gz | 4.4 GB |
|
|
| EGAF50000404218 | fastq.gz | 1.5 GB |
|
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| EGAF50000404219 | fastq.gz | 5.4 GB |
|
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| EGAF50000404220 | fastq.gz | 1.9 GB |
|
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| EGAF50000404221 | fastq.gz | 3.8 GB |
|
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| EGAF50000404222 | fastq.gz | 1.3 GB |
|
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| EGAF50000404223 | fastq.gz | 1.3 GB |
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| EGAF50000404224 | fastq.gz | 4.5 GB |
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| EGAF50000404225 | fastq.gz | 1.3 GB |
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| EGAF50000404226 | fastq.gz | 4.4 GB |
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| EGAF50000404227 | fastq.gz | 8.1 GB |
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| EGAF50000404228 | fastq.gz | 33.7 GB |
|
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| EGAF50000404229 | fastq.gz | 6.6 GB |
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| EGAF50000404230 | fastq.gz | 25.4 GB |
|
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| EGAF50000404231 | fastq.gz | 6.7 GB |
|
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| EGAF50000404232 | fastq.gz | 5.6 GB |
|
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| EGAF50000404233 | fastq.gz | 21.8 GB |
|
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| EGAF50000404234 | fastq.gz | 6.9 GB |
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| EGAF50000404235 | fastq.gz | 1.3 GB |
|
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| EGAF50000404236 | fastq.gz | 5.0 GB |
|
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| EGAF50000404237 | fastq.gz | 1.5 GB |
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| EGAF50000404238 | fastq.gz | 1.3 GB |
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| EGAF50000404239 | fastq.gz | 1.5 GB |
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| EGAF50000404240 | fastq.gz | 5.7 GB |
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| EGAF50000404241 | fastq.gz | 2.9 GB |
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| EGAF50000404242 | fastq.gz | 10.4 GB |
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| EGAF50000404243 | fastq.gz | 1.2 GB |
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| EGAF50000404244 | fastq.gz | 6.3 GB |
|
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| EGAF50000404245 | fastq.gz | 1.3 GB |
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| EGAF50000404246 | fastq.gz | 4.8 GB |
|
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| EGAF50000404247 | fastq.gz | 1.3 GB |
|
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| EGAF50000404248 | fastq.gz | 4.7 GB |
|
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| EGAF50000404249 | fastq.gz | 7.0 GB |
|
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| EGAF50000404250 | fastq.gz | 932.0 MB |
|
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| EGAF50000404251 | fastq.gz | 3.2 GB |
|
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| EGAF50000404252 | fastq.gz | 5.2 GB |
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| EGAF50000404253 | fastq.gz | 7.5 GB |
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| EGAF50000404254 | fastq.gz | 1.6 GB |
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| EGAF50000404255 | fastq.gz | 5.6 GB |
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| EGAF50000404256 | fastq.gz | 2.2 GB |
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| EGAF50000404257 | fastq.gz | 1.9 GB |
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| EGAF50000404258 | fastq.gz | 4.4 GB |
|
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| EGAF50000404259 | fastq.gz | 24.2 GB |
|
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| EGAF50000404260 | fastq.gz | 6.9 GB |
|
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| EGAF50000404261 | fastq.gz | 26.6 GB |
|
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| EGAF50000404262 | fastq.gz | 6.0 GB |
|
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| EGAF50000404263 | fq.gz | 3.4 GB |
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| EGAF50000404264 | fq.gz | 2.7 GB |
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| EGAF50000404265 | fq.gz | 2.7 GB |
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| EGAF50000404266 | fq.gz | 2.9 GB |
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| EGAF50000404267 | fq.gz | 2.6 GB |
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| EGAF50000404268 | fq.gz | 3.1 GB |
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| EGAF50000404269 | fq.gz | 3.3 GB |
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| EGAF50000404270 | fq.gz | 2.9 GB |
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| EGAF50000404271 | fq.gz | 3.1 GB |
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| EGAF50000404272 | fq.gz | 3.2 GB |
|
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| EGAF50000404273 | fq.gz | 3.0 GB |
|
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| EGAF50000404274 | fq.gz | 3.8 GB |
|
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| EGAF50000404275 | fq.gz | 2.9 GB |
|
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| EGAF50000404276 | fq.gz | 2.5 GB |
|
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| EGAF50000404277 | fastq.gz | 6.2 GB |
|
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| EGAF50000404278 | fastq.gz | 7.3 GB |
|
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| EGAF50000404279 | fastq.gz | 29.2 GB |
|
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| EGAF50000404280 | fastq.gz | 25.6 GB |
|
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| EGAF50000404281 | fastq.gz | 26.2 GB |
|
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| EGAF50000404282 | fastq.gz | 29.5 GB |
|
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| EGAF50000404283 | fastq.gz | 7.2 GB |
|
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| EGAF50000404284 | fastq.gz | 23.0 GB |
|
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| EGAF50000404285 | fastq.gz | 21.5 GB |
|
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| EGAF50000404286 | fastq.gz | 21.4 GB |
|
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| EGAF50000404287 | fastq.gz | 2.0 GB |
|
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| EGAF50000404288 | fastq.gz | 7.4 GB |
|
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| EGAF50000404289 | fastq.gz | 1.2 GB |
|
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| EGAF50000404290 | fastq.gz | 2.5 GB |
|
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| EGAF50000404291 | fq.gz | 2.4 GB |
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| EGAF50000404292 | fq.gz | 2.6 GB |
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| EGAF50000404293 | fq.gz | 3.6 GB |
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| EGAF50000404294 | fq.gz | 2.8 GB |
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| EGAF50000404295 | fq.gz | 2.9 GB |
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| EGAF50000404296 | fq.gz | 3.2 GB |
|
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| EGAF50000404297 | fq.gz | 3.3 GB |
|
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| EGAF50000404298 | fq.gz | 3.5 GB |
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| EGAF50000404299 | fq.gz | 3.7 GB |
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| EGAF50000404300 | fq.gz | 3.2 GB |
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| EGAF50000404301 | fastq.gz | 7.8 GB |
|
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| EGAF50000404302 | fastq.gz | 7.0 GB |
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| EGAF50000404303 | fastq.gz | 26.6 GB |
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| EGAF50000404304 | fastq.gz | 6.3 GB |
|
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| EGAF50000404305 | fastq.gz | 23.1 GB |
|
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| EGAF50000404306 | fastq.gz | 29.0 GB |
|
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| EGAF50000404307 | fastq.gz | 6.3 GB |
|
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| EGAF50000404308 | fastq.gz | 24.1 GB |
|
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| EGAF50000404309 | fastq.gz | 9.5 GB |
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| EGAF50000404310 | fastq.gz | 6.8 GB |
|
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| EGAF50000404311 | fastq.gz | 23.1 GB |
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| EGAF50000404312 | fastq.gz | 7.0 GB |
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| EGAF50000404313 | fastq.gz | 27.5 GB |
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| EGAF50000404314 | fastq.gz | 7.4 GB |
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| EGAF50000404315 | fastq.gz | 29.5 GB |
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| EGAF50000404316 | fastq.gz | 6.8 GB |
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| EGAF50000404317 | fastq.gz | 9.4 GB |
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| EGAF50000404318 | fastq.gz | 5.3 GB |
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| EGAF50000404319 | fastq.gz | 1.7 GB |
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| EGAF50000404320 | fastq.gz | 6.1 GB |
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| EGAF50000404321 | fastq.gz | 7.1 GB |
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| EGAF50000404322 | fastq.gz | 9.4 GB |
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| EGAF50000404323 | fastq.gz | 1.7 GB |
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| EGAF50000404324 | fastq.gz | 6.1 GB |
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| EGAF50000404325 | fastq.gz | 7.6 GB |
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| EGAF50000404326 | fastq.gz | 2.0 GB |
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| EGAF50000404327 | fastq.gz | 5.4 GB |
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| EGAF50000404328 | fastq.gz | 7.2 GB |
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| EGAF50000404329 | fastq.gz | 9.6 GB |
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| EGAF50000404330 | fastq.gz | 37.1 GB |
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| EGAF50000404331 | fastq.gz | 1.5 GB |
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| EGAF50000404332 | fastq.gz | 6.1 GB |
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| EGAF50000404333 | fastq.gz | 4.4 GB |
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| EGAF50000404334 | fastq.gz | 1.4 GB |
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| EGAF50000404335 | fastq.gz | 5.2 GB |
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| EGAF50000404336 | fastq.gz | 1.1 GB |
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| EGAF50000404337 | fastq.gz | 7.6 GB |
|
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| EGAF50000404338 | fastq.gz | 7.7 GB |
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| EGAF50000404339 | fastq.gz | 6.9 GB |
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| EGAF50000404340 | fastq.gz | 26.4 GB |
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| EGAF50000404341 | fastq.gz | 1.6 GB |
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| EGAF50000404342 | fastq.gz | 5.8 GB |
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| EGAF50000404343 | fastq.gz | 1.7 GB |
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| EGAF50000404344 | fastq.gz | 7.7 GB |
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| EGAF50000404345 | fastq.gz | 6.2 GB |
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| EGAF50000404346 | fastq.gz | 2.2 GB |
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| EGAF50000404347 | fastq.gz | 8.8 GB |
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| EGAF50000404348 | fastq.gz | 6.2 GB |
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| EGAF50000404349 | fastq.gz | 24.2 GB |
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| EGAF50000404350 | fastq.gz | 4.9 GB |
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| EGAF50000404351 | fastq.gz | 5.1 GB |
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| EGAF50000404352 | fastq.gz | 7.5 GB |
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| EGAF50000404353 | fastq.gz | 7.3 GB |
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| EGAF50000404354 | fastq.gz | 28.5 GB |
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| EGAF50000404355 | fastq.gz | 5.9 GB |
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| EGAF50000404356 | fastq.gz | 23.2 GB |
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| EGAF50000404357 | fastq.gz | 7.9 GB |
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| EGAF50000404358 | fastq.gz | 30.4 GB |
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| EGAF50000404359 | fastq.gz | 23.2 GB |
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| EGAF50000404360 | fastq.gz | 2.5 GB |
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| EGAF50000404361 | fastq.gz | 23.3 GB |
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| EGAF50000404362 | fastq.gz | 6.9 GB |
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| EGAF50000404363 | fastq.gz | 7.8 GB |
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| EGAF50000404364 | fastq.gz | 28.5 GB |
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| EGAF50000404365 | fastq.gz | 4.3 GB |
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| EGAF50000404366 | fastq.gz | 29.3 GB |
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| EGAF50000404367 | fastq.gz | 1.4 GB |
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| EGAF50000404368 | fastq.gz | 6.1 GB |
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| EGAF50000404369 | fastq.gz | 23.8 GB |
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| EGAF50000404370 | fastq.gz | 7.4 GB |
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| EGAF50000404371 | fastq.gz | 2.3 GB |
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| EGAF50000404372 | fastq.gz | 8.6 GB |
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| EGAF50000404373 | fastq.gz | 8.0 GB |
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| EGAF50000404374 | fastq.gz | 28.9 GB |
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| EGAF50000404375 | fastq.gz | 6.5 GB |
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| EGAF50000404376 | fastq.gz | 25.4 GB |
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| EGAF50000404377 | fastq.gz | 8.1 GB |
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| EGAF50000404378 | fastq.gz | 8.5 GB |
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| EGAF50000404379 | fastq.gz | 2.0 GB |
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| EGAF50000404380 | fastq.gz | 7.1 GB |
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| EGAF50000404381 | fastq.gz | 1.7 GB |
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| EGAF50000404382 | fastq.gz | 1.9 GB |
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| EGAF50000404383 | fastq.gz | 1.9 GB |
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| EGAF50000404384 | fastq.gz | 2.1 GB |
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| EGAF50000404385 | fastq.gz | 20.3 GB |
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| EGAF50000404386 | fastq.gz | 29.5 GB |
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| EGAF50000404387 | fastq.gz | 24.3 GB |
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| EGAF50000404388 | fastq.gz | 1.6 GB |
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| EGAF50000404389 | fastq.gz | 5.8 GB |
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| EGAF50000404390 | fastq.gz | 6.7 GB |
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| EGAF50000404391 | fastq.gz | 1.1 GB |
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| EGAF50000404392 | fastq.gz | 26.2 GB |
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| EGAF50000404393 | fastq.gz | 5.9 GB |
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| EGAF50000404394 | fastq.gz | 26.5 GB |
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| EGAF50000404395 | fastq.gz | 7.7 GB |
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| EGAF50000404396 | fastq.gz | 29.9 GB |
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| EGAF50000404397 | fastq.gz | 6.3 GB |
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| EGAF50000404398 | fastq.gz | 5.8 GB |
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| EGAF50000404399 | fastq.gz | 2.0 GB |
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| EGAF50000404400 | fastq.gz | 1.2 GB |
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| EGAF50000404401 | fastq.gz | 7.4 GB |
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| EGAF50000404402 | fastq.gz | 27.3 GB |
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| EGAF50000404403 | fastq.gz | 7.8 GB |
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| EGAF50000404404 | fastq.gz | 7.0 GB |
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| EGAF50000404405 | fastq.gz | 1.2 GB |
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| EGAF50000404406 | fastq.gz | 4.3 GB |
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| EGAF50000404407 | fastq.gz | 9.0 GB |
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| EGAF50000404408 | fastq.gz | 35.7 GB |
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| EGAF50000404409 | fastq.gz | 2.6 GB |
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| EGAF50000404410 | fastq.gz | 1.4 GB |
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| EGAF50000404411 | fastq.gz | 2.0 GB |
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| EGAF50000404412 | fastq.gz | 5.1 GB |
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| EGAF50000404413 | fastq.gz | 8.6 GB |
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| EGAF50000404414 | fastq.gz | 6.0 GB |
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| EGAF50000404415 | fastq.gz | 3.0 GB |
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| EGAF50000404416 | fastq.gz | 8.7 GB |
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| EGAF50000404417 | fastq.gz | 34.6 GB |
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| EGAF50000404418 | fastq.gz | 6.3 GB |
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| EGAF50000404419 | fastq.gz | 24.5 GB |
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| EGAF50000404420 | fastq.gz | 6.5 GB |
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| EGAF50000404421 | fastq.gz | 25.8 GB |
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| EGAF50000404422 | fastq.gz | 28.1 GB |
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| EGAF50000404423 | fastq.gz | 24.7 GB |
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| EGAF50000404424 | fastq.gz | 7.6 GB |
|
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| EGAF50000404425 | fastq.gz | 6.9 GB |
|
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| EGAF50000404426 | fastq.gz | 1.3 GB |
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| EGAF50000404427 | fastq.gz | 8.0 GB |
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| EGAF50000404428 | fastq.gz | 25.4 GB |
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| EGAF50000404429 | fastq.gz | 25.4 GB |
|
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| EGAF50000404430 | fastq.gz | 6.5 GB |
|
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| EGAF50000404431 | fastq.gz | 2.4 GB |
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| EGAF50000404432 | fastq.gz | 25.1 GB |
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| EGAF50000404433 | fastq.gz | 7.5 GB |
|
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| EGAF50000404434 | fastq.gz | 1.6 GB |
|
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| EGAF50000404435 | fastq.gz | 8.4 GB |
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| EGAF50000404436 | fastq.gz | 33.2 GB |
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| EGAF50000404437 | fastq.gz | 6.3 GB |
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| EGAF50000404438 | fastq.gz | 6.5 GB |
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| EGAF50000404439 | fastq.gz | 1.7 GB |
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| EGAF50000404440 | fastq.gz | 5.2 GB |
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| EGAF50000404441 | fastq.gz | 23.0 GB |
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| EGAF50000404442 | fastq.gz | 30.4 GB |
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| EGAF50000404443 | fastq.gz | 6.5 GB |
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|
| EGAF50000404444 | fastq.gz | 2.2 GB |
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| EGAF50000404445 | fastq.gz | 26.1 GB |
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|
| EGAF50000404446 | fastq.gz | 4.7 GB |
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|
| EGAF50000404447 | fastq.gz | 8.2 GB |
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| EGAF50000404448 | fastq.gz | 25.6 GB |
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|
| EGAF50000404449 | fastq.gz | 23.2 GB |
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| EGAF50000404450 | fastq.gz | 5.9 GB |
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| EGAF50000404451 | fastq.gz | 1.6 GB |
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| EGAF50000404452 | fastq.gz | 24.4 GB |
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|
| EGAF50000404453 | fastq.gz | 5.4 GB |
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|
| EGAF50000404454 | fastq.gz | 6.0 GB |
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|
| EGAF50000404455 | tsv.gz | 2.6 MB |
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|
| EGAF50000404456 | mtx.gz | 2.8 GB |
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|
| EGAF50000404457 | tsv.gz | 183.2 kB |
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|
| EGAF50000404458 | csv | 121.5 MB |
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|
| EGAF50000404459 | RDS | 12.2 GB |
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|
| EGAF50000404460 | vcf | 41.3 MB |
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| EGAF50000404461 | vcf | 40.5 MB |
|
|
| EGAF50000404462 | vcf | 39.7 MB |
|
|
| EGAF50000404463 | vcf | 35.5 MB |
|
|
| EGAF50000404464 | vcf | 46.6 MB |
|
|
| EGAF50000404465 | vcf | 38.8 MB |
|
|
| EGAF50000404466 | vcf | 33.7 MB |
|
|
| EGAF50000404467 | vcf | 36.4 MB |
|
|
| EGAF50000404468 | vcf | 65.5 MB |
|
|
| EGAF50000404469 | vcf | 32.0 MB |
|
|
| 320 Files (3.1 TB) | ||||
