scRNA and V(D)J sequencing of WM under ibrutinib
Single-cell RNA sequencing (5′ gene expression) and single-cell V(D)J sequencing (B-cell receptor and T-cell receptor) were performed on bone marrow mononuclear cells from patients with Waldenström macroglobulinemia treated with ibrutinib monotherapy. Sequential bone marrow aspirate samples were collected at baseline and after treatment. A total of 222 BAM files are included in this dataset.
- 10/02/2026
- 74 samples
- DAC: EGAC50000000863
- Technology: Illumina NovaSeq 6000
DUO:0000018 version: 2021-02-23
not for profit, non commercial use only
This data use modifier indicates that use of the data is limited to not-for-profit organizations and not-for-profit use, non-commercial use.
DUO:0000025 version: 2021-02-23
time limit on use
This data use modifier indicates that use is approved for a specific number of months.
DUO:0000042 version: 2021-02-23
general research use
This data use permission indicates that use is allowed for general research use for any research purpose.
Data access policy for single-cell RNA-seq and V(D)J profiling in Waldenström macroglobulinemia
Access to this dataset is restricted and will be granted only to qualified researchers for biomedical research purposes. The data consist of human single-cell RNA sequencing (5′ gene expression) and single-cell immune repertoire sequencing (B-cell receptor and T-cell receptor) generated from bone marrow mononuclear cells of patients with Waldenström macroglobulinemia undergoing ibrutinib monotherapy. Approved users may use the data solely for non-commercial biomedical research, including studies of cancer biology, immunology, and treatment response. Data access requests must include a clear research proposal and evidence of appropriate ethical approval or exemption, where applicable. Users must not attempt to re-identify study participants, must not share the data with unauthorized parties, and must comply with all relevant data protection regulations. Any secondary use of the data must be consistent with the scope of this policy and subject to approval by the Data Access Committee (DAC).
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000001596 | Transcriptome Sequencing |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
i
|
|---|---|---|---|---|
| EGAF50000581037 | bam | 1.3 GB |
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| EGAF50000581038 | bam | 1.5 GB |
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| EGAF50000581039 | bam | 820.3 MB |
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| EGAF50000581040 | bam | 1.1 GB |
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| EGAF50000581041 | bam | 324.6 MB |
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| EGAF50000581042 | bam | 419.5 MB |
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| EGAF50000581043 | bam | 1.6 GB |
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| EGAF50000581044 | bam | 219.5 MB |
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| EGAF50000581045 | bam | 478.5 MB |
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| EGAF50000581046 | bam | 778.2 MB |
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| EGAF50000581047 | bam | 996.1 MB |
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| EGAF50000581048 | bam | 337.0 MB |
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| EGAF50000581049 | bam | 1.8 GB |
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| EGAF50000581050 | bam | 481.6 MB |
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| EGAF50000581051 | bam | 1.0 GB |
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| EGAF50000581052 | bam | 1.4 GB |
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| EGAF50000581053 | bam | 719.5 MB |
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| EGAF50000581054 | bam | 483.8 MB |
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| EGAF50000581055 | bam | 873.6 MB |
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| EGAF50000581056 | bam | 723.7 MB |
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| EGAF50000581057 | bam | 1.2 GB |
|
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| EGAF50000581058 | bam | 1.4 GB |
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| EGAF50000581059 | bam | 1.4 GB |
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| EGAF50000581060 | bam | 1.3 GB |
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| EGAF50000581061 | bam | 1.4 GB |
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| EGAF50000581062 | bam | 1.9 GB |
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| EGAF50000581063 | bam | 893.5 MB |
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| EGAF50000581064 | bam | 843.9 MB |
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| EGAF50000581065 | bam | 913.7 MB |
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| EGAF50000581066 | bam | 946.5 MB |
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| EGAF50000581067 | bam | 942.8 MB |
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| EGAF50000581068 | bam | 403.9 MB |
|
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| EGAF50000581069 | bam | 1.3 GB |
|
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| EGAF50000581070 | bam | 599.7 MB |
|
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| EGAF50000581071 | bam | 420.1 MB |
|
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| EGAF50000581072 | bam | 631.6 MB |
|
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| EGAF50000581073 | bam | 1.8 GB |
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| EGAF50000581074 | bam | 1.6 GB |
|
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| EGAF50000581075 | bam | 1.6 GB |
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| EGAF50000581076 | bam | 1.3 GB |
|
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| EGAF50000581077 | bam | 896.2 MB |
|
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| EGAF50000581078 | bam | 1.5 GB |
|
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| EGAF50000581079 | bam | 666.2 MB |
|
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| EGAF50000581080 | bam | 847.8 MB |
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| EGAF50000581081 | bam | 1.1 GB |
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| EGAF50000581082 | bam | 825.3 MB |
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| EGAF50000581083 | bam | 725.9 MB |
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| EGAF50000581084 | bam | 662.5 MB |
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| EGAF50000581085 | bam | 1.6 GB |
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| EGAF50000581086 | bam | 681.9 MB |
|
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| EGAF50000581087 | bam | 1.1 GB |
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| EGAF50000581088 | bam | 1.3 GB |
|
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| EGAF50000581089 | bam | 583.7 MB |
|
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| EGAF50000581090 | bam | 1.2 GB |
|
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| EGAF50000581091 | bam | 931.2 MB |
|
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| EGAF50000581092 | bam | 1.1 GB |
|
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| EGAF50000581093 | bam | 583.8 MB |
|
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| EGAF50000581094 | bam | 439.0 MB |
|
|
| EGAF50000581095 | bam | 507.1 MB |
|
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| EGAF50000581096 | bam | 300.3 MB |
|
|
| EGAF50000581097 | bam | 1.3 GB |
|
|
| EGAF50000581098 | bam | 1.6 GB |
|
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| EGAF50000581099 | bam | 1.6 GB |
|
|
| EGAF50000581100 | bam | 1.7 GB |
|
|
| EGAF50000581101 | bam | 652.6 MB |
|
|
| EGAF50000581102 | bam | 2.1 GB |
|
|
| EGAF50000581103 | bam | 722.1 MB |
|
|
| EGAF50000581104 | bam | 239.2 MB |
|
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| EGAF50000581105 | bam | 687.4 MB |
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| EGAF50000581106 | bam | 1.3 GB |
|
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| EGAF50000581107 | bam | 1.3 GB |
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| EGAF50000581108 | bam | 4.3 GB |
|
|
| EGAF50000581109 | bam | 942.4 MB |
|
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| EGAF50000581110 | bam | 1.3 GB |
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| EGAF50000581111 | bam | 1.1 GB |
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| EGAF50000581112 | bam | 1.3 GB |
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| EGAF50000581113 | bam | 992.4 MB |
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| EGAF50000581114 | bam | 1.3 GB |
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| EGAF50000581115 | bam | 2.0 GB |
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| EGAF50000581116 | bam | 2.0 GB |
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| EGAF50000581117 | bam | 2.3 GB |
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| EGAF50000581118 | bam | 2.2 GB |
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| EGAF50000581119 | bam | 94.2 MB |
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| EGAF50000581120 | bam | 1.1 GB |
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| EGAF50000581121 | bam | 1.3 GB |
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| EGAF50000581122 | bam | 1.5 GB |
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| EGAF50000581123 | bam | 2.0 GB |
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| EGAF50000581124 | bam | 1.2 GB |
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| EGAF50000581125 | bam | 29.7 GB |
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| EGAF50000581126 | bam | 1.1 GB |
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| EGAF50000581127 | bam | 1.3 GB |
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| EGAF50000581128 | bam | 1.1 GB |
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| EGAF50000581129 | bam | 2.4 GB |
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| EGAF50000581130 | bam | 2.5 GB |
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| EGAF50000581131 | bam | 1.8 GB |
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| EGAF50000581132 | bam | 2.3 GB |
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| EGAF50000581133 | bam | 1.3 GB |
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| EGAF50000581134 | bam | 1.8 GB |
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| EGAF50000581135 | bam | 1.6 GB |
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| EGAF50000581136 | bam | 1.8 GB |
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| EGAF50000581137 | bam | 1.5 GB |
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| EGAF50000581138 | bam | 1.2 GB |
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| EGAF50000581139 | bam | 2.3 GB |
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| EGAF50000581140 | bam | 2.1 GB |
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| EGAF50000581141 | bam | 1.7 GB |
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| EGAF50000581142 | bam | 1.2 GB |
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| EGAF50000581143 | bam | 1.1 GB |
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| EGAF50000581144 | bam | 1.4 GB |
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| EGAF50000581145 | bam | 1.4 GB |
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| EGAF50000581146 | bam | 1.4 GB |
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| EGAF50000581147 | bam | 1.2 GB |
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| EGAF50000581148 | bam | 1.2 GB |
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| EGAF50000581149 | bam | 1.3 GB |
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| EGAF50000581150 | bam | 1.3 GB |
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| EGAF50000581151 | bam | 8.5 GB |
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| EGAF50000581152 | bam | 21.8 GB |
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| EGAF50000581153 | bam | 16.0 GB |
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| EGAF50000581154 | bam | 8.2 GB |
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| EGAF50000581155 | bam | 12.9 GB |
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| EGAF50000581156 | bam | 8.2 GB |
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| EGAF50000581157 | bam | 8.9 GB |
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| EGAF50000581158 | bam | 11.3 GB |
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| EGAF50000581159 | bam | 15.4 GB |
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| EGAF50000581160 | bam | 14.6 GB |
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| EGAF50000581161 | bam | 14.7 GB |
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| EGAF50000581162 | bam | 14.3 GB |
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| EGAF50000581163 | bam | 11.4 GB |
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| EGAF50000581164 | bam | 14.5 GB |
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| EGAF50000581165 | bam | 12.5 GB |
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| EGAF50000581166 | bam | 12.3 GB |
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| EGAF50000581167 | bam | 15.0 GB |
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| EGAF50000581168 | bam | 9.6 GB |
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| EGAF50000581169 | bam | 12.4 GB |
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| EGAF50000581170 | bam | 13.6 GB |
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| EGAF50000581171 | bam | 9.6 GB |
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| EGAF50000581172 | bam | 10.7 GB |
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| EGAF50000581173 | bam | 12.1 GB |
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| EGAF50000581174 | bam | 20.4 GB |
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| EGAF50000581175 | bam | 16.9 GB |
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| EGAF50000581176 | bam | 14.0 GB |
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| EGAF50000581177 | bam | 15.5 GB |
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| EGAF50000581178 | bam | 12.1 GB |
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| EGAF50000581179 | bam | 11.8 GB |
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| EGAF50000581180 | bam | 13.8 GB |
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| EGAF50000581181 | bam | 9.5 GB |
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| EGAF50000581182 | bam | 10.7 GB |
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| EGAF50000581183 | bam | 791.3 MB |
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| EGAF50000581184 | bam | 2.0 GB |
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| EGAF50000581185 | bam | 649.5 MB |
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| EGAF50000581186 | bam | 1.6 GB |
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| EGAF50000581187 | bam | 827.9 MB |
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| EGAF50000581188 | bam | 856.7 MB |
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| EGAF50000581189 | bam | 1.2 GB |
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| EGAF50000581190 | bam | 1.2 GB |
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| EGAF50000581191 | bam | 1.4 GB |
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| EGAF50000581192 | bam | 1.5 GB |
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| EGAF50000581193 | bam | 1.7 GB |
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| EGAF50000581194 | bam | 1.5 GB |
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| EGAF50000581195 | bam | 1.3 GB |
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| EGAF50000581196 | bam | 1.1 GB |
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| EGAF50000581197 | bam | 1.4 GB |
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| EGAF50000581198 | bam | 1.0 GB |
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| EGAF50000581199 | bam | 1.1 GB |
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| EGAF50000581200 | bam | 1.8 GB |
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| EGAF50000581201 | bam | 896.5 MB |
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| EGAF50000581202 | bam | 705.0 MB |
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| EGAF50000581203 | bam | 2.1 GB |
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| EGAF50000581204 | bam | 2.0 GB |
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| EGAF50000581205 | bam | 1.1 GB |
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| EGAF50000581206 | bam | 523.5 MB |
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| EGAF50000581207 | bam | 1.2 GB |
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| EGAF50000581208 | bam | 1.0 GB |
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| EGAF50000581209 | bam | 677.5 MB |
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| EGAF50000581210 | bam | 1.1 GB |
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| EGAF50000581211 | bam | 1.1 GB |
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| EGAF50000581212 | bam | 1.0 GB |
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| EGAF50000581213 | bam | 1.1 GB |
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| EGAF50000581214 | bam | 1.5 GB |
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| EGAF50000581215 | bam | 1.5 GB |
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| EGAF50000581216 | bam | 1.3 GB |
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| EGAF50000581217 | bam | 6.9 GB |
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| EGAF50000581218 | bam | 8.7 GB |
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| EGAF50000581219 | bam | 8.7 GB |
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| EGAF50000581220 | bam | 8.8 GB |
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| EGAF50000581221 | bam | 11.1 GB |
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| EGAF50000581222 | bam | 10.7 GB |
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| EGAF50000581223 | bam | 11.1 GB |
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| EGAF50000581224 | bam | 12.2 GB |
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| EGAF50000581225 | bam | 13.8 GB |
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| EGAF50000581226 | bam | 14.6 GB |
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| EGAF50000581227 | bam | 8.0 GB |
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| EGAF50000581228 | bam | 9.9 GB |
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| EGAF50000581229 | bam | 12.1 GB |
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| EGAF50000581230 | bam | 12.8 GB |
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| EGAF50000581231 | bam | 8.2 GB |
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| EGAF50000581232 | bam | 18.9 GB |
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| EGAF50000581233 | bam | 8.2 GB |
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| EGAF50000581234 | bam | 9.7 GB |
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| EGAF50000581235 | bam | 9.2 GB |
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| EGAF50000581236 | bam | 9.3 GB |
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| EGAF50000581237 | bam | 13.0 GB |
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| EGAF50000581238 | bam | 16.7 GB |
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| EGAF50000581239 | bam | 13.5 GB |
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| EGAF50000581240 | bam | 11.0 GB |
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| EGAF50000581241 | bam | 9.0 GB |
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| EGAF50000581242 | bam | 13.1 GB |
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| EGAF50000581243 | bam | 13.7 GB |
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| EGAF50000581244 | bam | 16.5 GB |
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| EGAF50000581245 | bam | 10.3 GB |
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| EGAF50000581246 | bam | 12.4 GB |
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| EGAF50000581247 | bam | 13.8 GB |
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| EGAF50000581248 | bam | 15.1 GB |
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| EGAF50000581249 | bam | 8.5 GB |
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| EGAF50000581250 | bam | 10.5 GB |
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| EGAF50000581251 | bam | 11.6 GB |
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| EGAF50000581252 | bam | 12.1 GB |
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| EGAF50000581253 | bam | 12.1 GB |
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| EGAF50000581254 | bam | 13.1 GB |
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| EGAF50000581255 | bam | 12.9 GB |
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| EGAF50000581256 | bam | 13.8 GB |
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| EGAF50000581257 | bam | 14.3 GB |
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| EGAF50000581258 | bam | 16.5 GB |
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| 222 Files (1.1 TB) | ||||
