WGS and RNA-seq data of PC9 erlotinib-resistant and sensitive cell lines
This dataset contains whole genome sequencing (WGS) and RNA sequencing (RNA-seq) FASTQ files from two PC9 NSCLC cell lines: erlotinib-resistant (PC9-ER-R) and erlotinib-sensitive parental (PC9-ER-S). A total of 4 paired-end FASTQ file pairs were generated using Illumina NovaSeq 6000, comprising 2 WGS and 2 RNA-seq libraries. Data were generated to investigate RAF1 ecDNA-mediated acquired erlotinib resistance mechanisms.
- 08/06/2026
- 2 samples
- DAC: EGAC50000001001
- Technology: Illumina NovaSeq 6000
DUO:0000006 version: 2021-02-23
health or medical or biomedical research
This data use permission indicates that use is allowed for health/medical/biomedical purposes; does not include the study of population origins or ancestry.
DUO:0000018 version: 2021-02-23
not for profit, non commercial use only
This data use modifier indicates that use of the data is limited to not-for-profit organizations and not-for-profit use, non-commercial use.
NSCLC PC9 erlotinib RAF1 Data Access Policy
Access to this dataset is restricted to researchers conducting non-commercial academic research related to cancer genomics and drug resistance mechanisms. Requestors must submit a research proposal outlining the intended use of the data. Data must not be shared with third parties without prior approval from the DAC.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000001832 | Cancer Genomics |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
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| EGAF50000835893 | fastq.gz | 31.9 GB |
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| EGAF50000835894 | fastq.gz | 30.5 GB |
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| EGAF50000835895 | fastq.gz | 30.5 GB |
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| EGAF50000835896 | fastq.gz | 29.1 GB |
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| EGAF50000835897 | fastq.gz | 2.2 GB |
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| EGAF50000835898 | fastq.gz | 2.3 GB |
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| EGAF50000835899 | fastq.gz | 2.4 GB |
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| EGAF50000835900 | fastq.gz | 2.5 GB |
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| 8 Files (131.5 GB) | ||||
