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Bulk RNA sequencing of metastatic colorectal cancer PDX-derived organoids - untreated and treated with IL-6 or TGF-beta1

Bulk RNA sequencing was performed on patient-derived xenograft (PDX)-derived organoid models of metastatic colorectal cancer (mCRC). The aim of this study was to test the effect of IL-6 and TGF-beta1 on mCRC organoid cell differentiation. Transcriptomic profiling was conducted following cytokine treatments to investigate molecular changes associated with treatments.

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DUO:0000007
version: 2021-02-23

disease specific research

This data use permission indicates that use is allowed provided it is related to the specified disease.

ModifiersMONDO:0005575

Quantitative Cancer Cell Biology EGA Policy

Dataset available on request.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000001914 Transcriptome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF50000909968 fastq.gz 3.1 GB
EGAF50000909969 fastq.gz 3.5 GB
EGAF50000909970 fastq.gz 2.7 GB
EGAF50000909971 fastq.gz 2.9 GB
EGAF50000909972 fastq.gz 2.5 GB
EGAF50000909973 fastq.gz 2.7 GB
EGAF50000909974 fastq.gz 3.4 GB
EGAF50000909975 fastq.gz 3.1 GB
EGAF50000909976 fastq.gz 2.8 GB
EGAF50000909977 fastq.gz 3.0 GB
EGAF50000909978 fastq.gz 2.8 GB
EGAF50000909979 fastq.gz 3.0 GB
EGAF50000909980 fastq.gz 3.5 GB
EGAF50000909981 fastq.gz 3.3 GB
EGAF50000909982 fastq.gz 3.3 GB
EGAF50000909983 fastq.gz 3.5 GB
EGAF50000909984 fastq.gz 3.4 GB
EGAF50000909985 fastq.gz 3.9 GB
18 Files (56.3 GB)