About file location

As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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Lothian Birth Cohort 1936 single nuclei RNA sequencing dataset of central white matter

Nuclei isolated from central white matter samples from 14 members of the LBC1936 were sequenced across 3xP3 flowcells using the Illumina NextSeq2000 platform. This dataset contains the paired-end FASTQ reads from each flowcell for each individual.

Request Access

DUO:0000006
version: 2019-01-07

health or medical or biomedical research

This data use permission indicates that use is allowed for health/medical/biomedical purposes; does not include the study of population origins or ancestry.

DUO:0000014
version: 2019-01-07

research use only

This data use limitation indicates that use is limited to research purposes (e.g., does not include its use in clinical care).

DUO:0000019
version: 2019-01-07

publication required

This data use modifier indicates that requestor agrees to make results of studies using the data available to the larger scientific community.

DUO:0000025
version: 2019-01-07

time limit on use

This data use modifier indicates that use is approved for a specific number of months.

DUO:0000026
version: 2019-01-07

user specific restriction

This data use modifier indicates that use is limited to use by approved users.

DUO:0000027
version: 2019-01-07

project specific restriction

This data use modifier indicates that use is limited to use within an approved project.

DUO:0000028
version: 2019-01-07

institution specific restriction

This data use modifier indicates that use is limited to use within an approved institution.

DUO:0000029
version: 2019-01-07

return to database or resource

This data use modifier indicates that the requestor must return derived/enriched data to the database/resource.

Data access agreement for accessing the Lothian Birth Cohorts genetic and phenotypic data.

DATA ACCESS AGREEMENT Transfer of Data THIS AGREEMENT SETS OUT THE TERMS AND CONDITIONS ON WHICH ACCESS WILL BE GRANTED TO THE DATA SPECIFIED BELOW. BY SIGNING THIS AGREEMENT YOU AGREE TO BE BOUND BY THESE TERMS AND CONDITIONS 1. Defined Terms For the purpose of this Agreement, the following terms shall be understood to mean: “Agreement” this Data Access Agreement. “Confidential Information” any information of a confidential nature disclosed by Edinburgh to You in whatever form (whether written, oral, visual or electronic). “Data” [INSERT DESCRIPTION OF DATA]… all of which forms part of the Database. A full list of data items is appended with a Data Request Form. ] “Database” the Lothian Birth Cohort 1936 and the Lothian Birth Cohort 1921 Study Databases. “Derived Data” the data, datasets, algorithms and /or derived variables used therein which may be derived from the use or analysis of the Data by You in carrying out the Project. “Edinburgh” The University Court Of The University Of Edinburgh, a charitable body registered in Scotland under registration number SC005336, incorporated under the Universities (Scotland) Acts and having its main administrative offices at Old College, South Bridge Edinburgh, EH8 9YL. “Edinburgh Scientist” Dr Simon Cox, Director of the Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, 7 George Square Edinburgh, EH8 9JZ. “Intellectual Property” means (i) patents, designs, trade marks and trade names (whether registered or unregistered), copyright and related rights, database rights, know-how and confidential information; (ii) all other intellectual property rights and similar or equivalent rights anywhere in the world which currently exist or are recognised in the future; and (iii) applications, extensions and renewals in relation to such rights. “Project” the project entitled “TBC”. “Recipient Institution” TBC “Recipient Scientist(s)” TBC “Term” TBC years “You” the Recipient Institution and/or the Recipient Scientist. 2. Use of the Data 2.1 You acknowledge and agree that only the Recipient Scientist(s) is/are permitted to have access to and to use the Data. The Recipient Scientist(s) will access and use the Data solely for the purpose of carrying out the Project and will not access or use the Data for any other purpose without prior written consent from Edinburgh. Recipient Institution shall in any event procure acceptance of the terms of this Agreement by all persons who have access to the Data. 2.2 You will comply with all security and operating requirements notified to you by Edinburgh and will use the Data in accordance with all applicable laws, regulations and research governance. 2.3 You undertake to make no attempt to link the Data to any other datasets whatsoever (including, without limitation, any external datasets or any datasets from the same patient cohort) held by different recipients or by You for different projects, without prior written consent from Edinburgh, or to use the Data to identify the Data subjects. 2.4 You will not use the Data for any commercial purpose or any purpose that is subject to consulting or licensing obligations to third parties without prior written consent from Edinburgh. 3. Ownership of Data, Derived Data and Intellectual Property 3.1 The Data and all intellectual property rights therein will remain the property of Edinburgh at all times and no right, title or interest in or to the Data is granted to You other than as expressly set out in this Agreement. 3.2 The Derived Data and all intellectual property rights therein will be owned by Edinburgh. Edinburgh agrees to provide You with a copy of the Derived Data and hereby grants to You a non-exclusive, royalty-free perpetual licence to use the Derived Data for health research purposes. 3.3 You shall have the right to develop Intellectual Property based on comparisons with your own data. 4. Confidentiality 4.1 You shall keep confidential the Data and any Confidential Information for so long as such Data and/or Confidential Information remain confidential in nature, notwithstanding termination or expiry of this Agreement. 4.2 The obligation in Clause 4.1 shall not apply where You can prove that the Data and/or Confidential Information: (a) has become public knowledge, other than through an unauthorised disclosure by You; (b) was already known to You prior to disclosure by Edinburgh or was independently developed by You without use of or recourse to the Data and/or Confidential Information; (c) was disclosed to You by a third party not under any obligation of confidence to Edinburgh; or (d) is required to be disclosed by law or by requirement of a regulatory body or court order. 5. Collaboration and Publications You agree to use reasonable endeavours to collaborate with Edinburgh with regard to Your analysis of the Data, with a view to publishing the results arising from Your analysis of the Data, jointly with Edinburgh. In any event, you agree that any publications made by You of results arising from Your analysis of the Data will be produced in accordance with normal academic practice including (without limitation) appropriate acknowledgement of co-authors, any published paper from which the Data derives, the version of the Data used, the role of Edinburgh, the relevant primary collectors of the Data and their funders. 6. DISCLAIMERS 6.1 YOU ACKNOWLEDGE AND AGREE THAT ACCESS TO, AND USE OF, THE DATA AND DERIVED DATA IS PROVIDED BY EDINBURGH ON AN “AS IS” BASIS. EDINBURGH GIVES NO WARRANTY, EXPRESS OR IMPLIED, THAT:- (a) THE DATA AND DERIVED DATA IS ACCURATE OR COMPLETE; (b) THE DATA AND DERIVED DATA IS FIT FOR ANY PARTICULAR PURPOSE; (c) YOUR USE OF THE DATA AND DERIVED DATA WILL NOT INFRINGE ANY THIRD PARTY INTELLECTUAL PROPERTY OR OTHER RIGHTS. 6.2 EACH PARTY AGREES THAT NEITHER PARTY SHALL BE LIABLE FOR ANY INDIRECT OR CONSEQUENTIAL DAMAGES INCURRED BY THE OTHER PARTY UNDER OR IN CONNECTION WITH THIS AGREEMENT HOWSOEVER CAUSED. 6.3 Nothing in this Agreement excludes, restricts or otherwise limits either party’s liability for any death or personal injury arising from its negligence or for any loss suffered by the other party as a result of it’s fraud. 7. Term and Termination of Access 7.1 You agree that You will access the Data during the Term only. You accept and agree that: (a) Edinburgh may terminate Your access to the Data forthwith upon any breach of this Agreement by You; and (b) Edinburgh may terminate Your access to the Data upon giving You one month’s written notice. 7.2 On termination or expiry of this Agreement You shall immediately destroy all tangible copies of the Data in Your possession and (to the extent possible to do so) delete all copies of the Data from Your computer systems and confirm in writing to Edinburgh that this has been done. 7.3 You acknowledge and agree that the provisions of this Agreement will continue in full force and effect following expiry of the Term or termination of Your access to the Data by Edinburgh pursuant to Clause 7.1. 8. Additional Data 8.1 If agreed in written with the Edinburgh Scientist, additional data items may be supplied to the Recipient Institution to facilitate the analysis as part of the Project, on the same terms as are contained in this Agreement. 9. Applicable law and jurisdiction You agree that Scots law shall govern this Agreement and the Scottish courts shall have exclusive jurisdiction over any matter relating to it. Edinburgh hereby accepts the foregoing terms and conditions: For and on behalf of Edinburgh: Signed: Date: Name: Title: The Recipient Institution hereby accepts the foregoing terms and conditions: For and on behalf of the Recipient Institution: Signed: Date: Name: Title: As the Recipient Scientist, I acknowledge receipt of a copy of this Agreement and confirm that I will abide by its terms insofar as those terms are applicable to me: Signed: Date: Name: LBC1921/36 Data request form Provisional title of study Principal researcher (include institution address, email & phone) Provisional author list Brief rationale for study Main variables to be analysed (variable names from data dictionary) Which journal(s) are you considering?

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000001978 Transcriptome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF00009195212 fastq.gz 1.3 GB
EGAF00009195223 fastq.gz 1.3 GB
EGAF00009195225 fastq.gz 1.3 GB
EGAF00009195231 fastq.gz 1.3 GB
EGAF00009195233 fastq.gz 2.8 GB
EGAF00009195243 fastq.gz 2.9 GB
EGAF00009195246 fastq.gz 1.3 GB
EGAF00009195247 fastq.gz 1.3 GB
EGAF00009195249 fastq.gz 2.8 GB
EGAF00009195258 fastq.gz 2.8 GB
EGAF00009195267 fastq.gz 2.9 GB
EGAF00009196710 fastq.gz 1.0 GB
EGAF00009196719 fastq.gz 2.2 GB
EGAF00009196720 fastq.gz 1.0 GB
EGAF00009196725 fastq.gz 2.9 GB
EGAF00009196732 fastq.gz 2.2 GB
EGAF00009196735 fastq.gz 2.2 GB
EGAF00009196736 fastq.gz 1.0 GB
EGAF00009196737 fastq.gz 1.0 GB
EGAF00009196743 fastq.gz 1.0 GB
EGAF00009196746 fastq.gz 1.0 GB
EGAF00009196747 fastq.gz 766.6 MB
EGAF00009196748 fastq.gz 2.2 GB
EGAF00009196754 fastq.gz 2.2 GB
EGAF00009196757 fastq.gz 771.5 MB
EGAF00009196762 fastq.gz 1.7 GB
EGAF00009196765 fastq.gz 935.6 MB
EGAF00009196773 fastq.gz 2.2 GB
EGAF00009196774 fastq.gz 1.7 GB
EGAF00009196775 fastq.gz 934.8 MB
EGAF00009196782 fastq.gz 931.4 MB
EGAF00009196784 fastq.gz 2.1 GB
EGAF00009196790 fastq.gz 929.9 MB
EGAF00009196792 fastq.gz 2.1 GB
EGAF00009196798 fastq.gz 1.0 GB
EGAF00009196799 fastq.gz 2.0 GB
EGAF00009196808 fastq.gz 801.3 MB
EGAF00009196810 fastq.gz 2.0 GB
EGAF00009196818 fastq.gz 795.9 MB
EGAF00009196820 fastq.gz 2.2 GB
EGAF00009196827 fastq.gz 808.1 MB
EGAF00009196829 fastq.gz 1.7 GB
EGAF00009196831 fastq.gz 2.2 GB
EGAF00009196835 fastq.gz 1.7 GB
EGAF00009196836 fastq.gz 799.7 MB
EGAF00009196839 fastq.gz 1.0 GB
EGAF00009196844 fastq.gz 695.1 MB
EGAF00009196846 fastq.gz 1.7 GB
EGAF00009196853 fastq.gz 721.7 MB
EGAF00009196859 fastq.gz 1.7 GB
EGAF00009196860 fastq.gz 1.5 GB
EGAF00009196862 fastq.gz 852.3 MB
EGAF00009196869 fastq.gz 1.6 GB
EGAF00009196871 fastq.gz 872.5 MB
EGAF00009196874 fastq.gz 857.3 MB
EGAF00009196883 fastq.gz 1.9 GB
EGAF00009196884 fastq.gz 878.3 MB
EGAF00009196891 fastq.gz 888.2 MB
EGAF00009196897 fastq.gz 888.9 MB
EGAF00009196899 fastq.gz 1.9 GB
EGAF00009196902 fastq.gz 1.9 GB
EGAF00009196908 fastq.gz 1.9 GB
EGAF00009196911 fastq.gz 1.1 GB
EGAF00009196915 fastq.gz 1.9 GB
EGAF00009196924 fastq.gz 1.1 GB
EGAF00009196925 fastq.gz 1.9 GB
EGAF00009196928 fastq.gz 1.1 GB
EGAF00009196932 fastq.gz 1.1 GB
EGAF00009196934 fastq.gz 2.3 GB
EGAF00009196938 fastq.gz 689.8 MB
EGAF00009196942 fastq.gz 2.3 GB
EGAF00009196945 fastq.gz 708.9 MB
EGAF00009196949 fastq.gz 2.3 GB
EGAF00009196953 fastq.gz 1.5 GB
EGAF00009196958 fastq.gz 2.3 GB
EGAF00009196961 fastq.gz 1.0 GB
EGAF00009196962 fastq.gz 1.6 GB
EGAF00009196968 fastq.gz 1.1 GB
EGAF00009196981 fastq.gz 2.3 GB
EGAF00009196983 fastq.gz 1.1 GB
EGAF00009196987 fastq.gz 892.2 MB
EGAF00009196990 fastq.gz 2.3 GB
EGAF00009196992 fastq.gz 1.1 GB
EGAF00009196996 fastq.gz 2.3 GB
EGAF00009196997 fastq.gz 922.7 MB
EGAF00009197004 fastq.gz 2.0 GB
EGAF00009197006 fastq.gz 965.2 MB
EGAF00009197011 fastq.gz 987.0 MB
EGAF00009197015 fastq.gz 2.0 GB
EGAF00009197021 fastq.gz 974.2 MB
EGAF00009197027 fastq.gz 2.4 GB
EGAF00009197033 fastq.gz 995.4 MB
EGAF00009197035 fastq.gz 2.1 GB
EGAF00009197040 fastq.gz 2.2 GB
EGAF00009197041 fastq.gz 914.9 MB
EGAF00009197045 fastq.gz 2.1 GB
EGAF00009197051 fastq.gz 2.2 GB
EGAF00009197059 fastq.gz 932.4 MB
EGAF00009197061 fastq.gz 1.0 GB
EGAF00009197062 fastq.gz 2.1 GB
EGAF00009197064 fastq.gz 1.0 GB
EGAF00009197068 fastq.gz 1.0 GB
EGAF00009197070 fastq.gz 2.0 GB
EGAF00009197073 fastq.gz 2.3 GB
EGAF00009197075 fastq.gz 1.0 GB
EGAF00009197077 fastq.gz 764.0 MB
EGAF00009197079 fastq.gz 2.3 GB
EGAF00009197093 fastq.gz 796.9 MB
EGAF00009197094 fastq.gz 2.3 GB
EGAF00009197101 fastq.gz 1.6 GB
EGAF00009197103 fastq.gz 2.3 GB
EGAF00009197108 fastq.gz 913.3 MB
EGAF00009197110 fastq.gz 1.7 GB
EGAF00009197111 fastq.gz 941.6 MB
EGAF00009197116 fastq.gz 684.0 MB
EGAF00009197121 fastq.gz 2.0 GB
EGAF00009197126 fastq.gz 948.7 MB
EGAF00009197130 fastq.gz 2.0 GB
EGAF00009197133 fastq.gz 707.3 MB
EGAF00009197138 fastq.gz 2.0 GB
EGAF00009197142 fastq.gz 735.5 MB
EGAF00009197145 fastq.gz 2.0 GB
EGAF00009197153 fastq.gz 1.6 GB
EGAF00009197155 fastq.gz 1.0 GB
EGAF00009197157 fastq.gz 1.5 GB
EGAF00009197162 fastq.gz 1.1 GB
EGAF00009197167 fastq.gz 1.0 GB
EGAF00009197175 fastq.gz 1.1 GB
EGAF00009197178 fastq.gz 2.3 GB
EGAF00009197179 fastq.gz 794.3 MB
EGAF00009197183 fastq.gz 2.3 GB
EGAF00009197188 fastq.gz 832.8 MB
EGAF00009197189 fastq.gz 2.3 GB
EGAF00009197196 fastq.gz 1.8 GB
EGAF00009197199 fastq.gz 1.1 GB
EGAF00009197204 fastq.gz 1.8 GB
EGAF00009197208 fastq.gz 1.1 GB
EGAF00009197215 fastq.gz 1.1 GB
EGAF00009197216 fastq.gz 2.4 GB
EGAF00009197222 fastq.gz 2.4 GB
EGAF00009197225 fastq.gz 1.1 GB
EGAF00009197230 fastq.gz 2.5 GB
EGAF00009197233 fastq.gz 1.2 GB
EGAF00009197242 fastq.gz 1.2 GB
EGAF00009197249 fastq.gz 2.4 GB
EGAF00009197251 fastq.gz 1.1 GB
EGAF00009197259 fastq.gz 2.5 GB
EGAF00009197260 fastq.gz 2.5 GB
EGAF00009197261 fastq.gz 1.1 GB
EGAF00009197264 fastq.gz 2.6 GB
EGAF00009197268 fastq.gz 1.1 GB
EGAF00009197270 fastq.gz 2.3 GB
EGAF00009197275 fastq.gz 1.1 GB
EGAF00009197277 fastq.gz 783.5 MB
EGAF00009197278 fastq.gz 2.3 GB
EGAF00009197286 fastq.gz 797.3 MB
EGAF00009197289 fastq.gz 2.3 GB
EGAF00009197294 fastq.gz 1.7 GB
EGAF00009197298 fastq.gz 2.4 GB
EGAF00009197301 fastq.gz 1.7 GB
EGAF00009197303 fastq.gz 966.8 MB
EGAF00009197309 fastq.gz 960.1 MB
EGAF00009197310 fastq.gz 964.8 MB
EGAF00009197313 fastq.gz 2.1 GB
EGAF00009197316 fastq.gz 972.2 MB
EGAF00009197320 fastq.gz 2.1 GB
EGAF00009197324 fastq.gz 2.1 GB
EGAF00009197380 fastq.gz 2.1 GB
168 Files (259.9 GB)