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Single-cell RNA sequencing of healthy human duodenum as a control cohort for cirrhosis and short bowel syndrome studies

This dataset contains single-cell transcriptomes of the healthy human duodenum, profiled with the 10x Genomics platform. It was produced to act as the control group in two separate studies: one on how cirrhosis alters the duodenum, and one on short bowel syndrome and its response to apraglutide. It includes 10 samples from 5 healthy donors, with each donor sequenced twice. Together, the samples provide a healthy baseline for comparison with the disease and treatment conditions.

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Data policy of Data Access Committee of UZ Leuven

The procedure described below always applies to re-use transfer of genomic or genetic data that are in an external database. This external database can be the European Genome-phenome Archive (EGA). When a researcher receives requests for reuse of data, or when the database requires an intervention of a data access committee, the DAC will assess these requests for reuse and transfer of genomic or genetic data by third parties. Patient consent to research participation (ICF) and compatibility with new data processing should be checked. An application should be submitted at dac@uzleuven.be. So applications for re-use of genomic/genomic data go through the DAC. In the first place, DAC performs a front desk function here. An application form should be completed by the applicant. To begin with, the DAC employee then checks the ICF and its compatibility with further use. The DAC employee also ensures that a check is made with the competent services to ensure that there are no legal impediments. If i) there are possible commercial interests (commercial use of the data by the recipient or the requesting party is a commercial party), ii) the researcher does not agree, or iii) there is some ambiguity about potential risks of the data transfer (e.g. violation (GDPR) legislation, identity of recipient party, use of the data), the question is referred to the DAC advisory board.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000002194 Transcriptome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF50001047980 fastq.gz 4.0 GB
EGAF50001047981 fastq.gz 9.0 GB
EGAF50001047982 fastq.gz 3.9 GB
EGAF50001047983 fastq.gz 8.8 GB
EGAF50001047984 fastq.gz 5.7 GB
EGAF50001047985 fastq.gz 13.1 GB
EGAF50001047986 fastq.gz 5.2 GB
EGAF50001047987 fastq.gz 11.9 GB
EGAF50001047988 fastq.gz 4.3 GB
EGAF50001047989 fastq.gz 9.6 GB
EGAF50001047990 fastq.gz 3.5 GB
EGAF50001047991 fastq.gz 7.8 GB
EGAF50001047992 fastq.gz 5.1 GB
EGAF50001047993 fastq.gz 11.4 GB
EGAF50001047994 fastq.gz 5.9 GB
EGAF50001047995 fastq.gz 13.2 GB
EGAF50001047996 fastq.gz 1.9 GB
EGAF50001047997 fastq.gz 4.2 GB
EGAF50001047998 fastq.gz 4.1 GB
EGAF50001047999 fastq.gz 9.1 GB
20 Files (141.5 GB)