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• Triple_Negative_Breast_Cancer_Whole_Genomes

  We propose to definitively characterise the somatic genetics of Triple negative breast cancer through generation of comprehensive catalogues of somatic mutations in 500 cases by high coverage genome sequencing coupled with integrated transcriptomic and methylation analyses.

  Study EGAS00001000092

• Characterization of Arabian Peninsula whole exomes

  We conducted whole exome sequencing (using the SureSelect Human All Exon V5 + UTRs target enrichment kit) of 90 individuals from AP (23 from Saudi Arabia, 24 from Yemen, 24 from Oman and 19 from UAE).

  Study EGAS00001006487

• Single-cell TCR sequencing of gluten-specific T cells from 20 celiac disease patients uploaded on 2021_Data access committee

  In order to characterize the T cell receptor (TCR) repertoire of gluten specific T cells, we performed high-throughput DNA sequencing of rearranged TCR-α and TCR-β genes of the single HLA-DQ2.5:DQ2.5-gluten tetramer binding CD4+ T cells isolated from blood, biopsies and T cell line from celiac disease patients.

  Dataset EGAD00001006977

• Renal Cancer Exome Sequencing

  Agilent whole exome hybridisation capture will be performed on genomic DNA derived from 25 renal cancers and matched normal DNA from the same patients. Three lanes of Illumina GA sequencing will be performed on the resulting 50 exome libraries and mapped to build 37 of the human reference genome to facilitate the identification of novel cancer genes.

  Dataset EGAD00001000014

• Familial_Thrombocytosis_germline_exome_sequencing

  Agilent whole exome hybridisation capture will be performed on genomic DNA derived from 3 relatives from a family with multiple affected familial thrombocytosis (FT) patients. Germline DNA from 2-4 patients affected with FT will be used to prepare libraries and sequenced in one lane of HiSeq sequencing, mapped to build 37 of the human reference genome to facilitate the identification of novel cancer genes.

  Study EGAS00001000088

• NPC genome-wide human SNP array data for HongKong population

  nasopharyngeal carcinoma genome-wide human SNP array data for 423 NPC cases and 573 controls

  Dataset EGAD00010002298

• WGS data for MMML (EGAS00001002422)

  Whole genome sequencing data for MMML (7 tumors and 8 controls)

  Dataset EGAD00001003286

• RNA data for MMML (EGAS00001002422)

  RNA sequencing data for MMML (3 tumor samples and 1 gcbcell)

  Dataset EGAD00001003285

• RNA-seq for 8 samples

  This dataset contains RNA-seq data from 8 acute leukemia cases (diagnosis or relapse) belonging to a newly identified subtype, termed FOXF1/FENDRR ALL. All the 8 samples are in bam file type.

  Dataset EGAD50000001789

• Genomic Profiling of Advanced Pancreatic Cancer to inform therapy - RNA-Seq mapped reads

  Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer - Early Results from the COMPASS Trial - RNA-Seq mapped reads

  Dataset EGAD00001003584