7082 results for "canc*"

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• Normal sample for patient SA219

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA219

  Dataset EGAD00001009221

• Normal sample for patient SA275

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA275

  Dataset EGAD00001009224

• Normal sample for patient SA588

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA588

  Dataset EGAD00001009238

• Normal sample for patient SA590

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA590

  Dataset EGAD00001009240

• Cancer initiation organoids BAM files

  This dataset contains whole-genome sequencing data files from colon organoid cultures, which were mutated using CRISPR-Cas9 for specific genes (APC, KRAS, TP53 and SMAD4) to generate in vitro transformed cancer cells. After introducing each mutation, the resulting cultures were subjected to whole-genome sequencing. In addition, some cultures were xenotransplanted in recipient mice. The resulting primary tumors and corresponding metastases were subjected to whole-genome sequencing.

  Dataset EGAD00001002719

• CYPTAM - PacBio SMRT sequencing

  Dataset contains CYP2D6 sequencing data of 566 individuals who used tamoxifen as adjuvant breast cancer therapy. Phenotype data consists of the ratio between the metabolites endoxifen and desmethyltamoxifen (Metabolic ratio (MR)) as a proxy for CYP2D6 enzyme activity. Each sample is linked to one bam-file containing the CYP2D6 sequence.

  Dataset EGAD00001005972

• Anaplastic Thyroid Cancer somatic variants (SomaticSniper)

  Sequence was aligned to the GRCH38 reference genome. Aligned sequence was analyzed with SomaticSniper. Somatic variant calls are in VCF format. In total there are 94 tumour samples, each with a matched normal.

  Dataset EGAD00001004128

• Normal sample for patient SA593

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA593

  Dataset EGAD00001009243

• Normal sample for patient SA595

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA595

  Dataset EGAD00001009244

• Normal sample for patient SA599

  Whole genome sequencing of normal sample for triple negative breast cancer patient SA599

  Dataset EGAD00001009247