COLON, Colorectal Cancer: Longitudinal Observational study on Nutritional and lifestyle factors that influence colorectal tumor recurrence, survival and quality of life: The COLON study is a multi-center prospective cohort study to assess the role of diet and other lifestyle factors in cancer recurrence and survival among incident colorectal cancer patients in the Netherlands. DACHS, Darmkrebs: Chancen der Verhütung durch Screening:This German study was initiated as a large population-based case-control study in 2003 in the Rhine-Neckar-Odenwald region (southwest region of Germany) to assess the potential of endoscopic screening for reduction of colorectal cancer risk and to investigate etiologic determinants of disease, particularly lifestyle/environmental factors and genetic factors. During an in-person interview, data were collected on demographics, medical history, family history of CRC, and various life-style factors, as were blood and mouthwash samples. EPIC, European Prospective Investigation into Cancer: EPIC is an on-going multicenter prospective cohort study designed to investigate the associations between diet, lifestyle, genetic and environmental factors and various types of cancer. HPFS, Health Professionals Follow-up Study: HPFS is a parallel prospective study to the NHS. The HPFS cohort comprised 51,529 men aged 40-75 who, in 1986, responded to a mailed questionnaire. Participants provided information on health related exposures, including current and past smoking history, age, weight, height, diet, physical activity, aspirin use, and family history of colorectal cancer. Colorectal cancer and other outcomes were reported by participants or next-of-kin and were followed up through review of the medical and pathology record by physicians. Overall, more than 97% of self-reported colorectal cancers were confirmed by medical record review. Information was abstracted on histology and primary location. Follow-up evaluation has been excellent, with 94% of the men responding to date. NHS, Nurses' Health Study: The NHS cohort began in 1976 when 121,700 married female registered nurses age 30-55 years returned the initial questionnaire that ascertained a variety of important health-related exposures [PMID:248266]. Since 1976, follow-up questionnaires have been mailed every 2 years. Colorectal cancer and other outcomes were reported by participants or next-of-kin and followed up through review of the medical and pathology record by physicians. Overall, more than 97% of self-reported colorectal cancers were confirmed by medical-record review. Information was abstracted on histology and primary location. The rate of follow-up evaluation has been high: as a proportion of the total possible follow-up time, follow-up evaluation has been more than 92%. NQplus, Nutrition Questionnaires plus: NQplus is a longitudinal observational study on diet and health in the general Dutch population.
Sequence of breast cancer bone metastases PDX obtained by 2 targeted panels
This dataset contains Whole Exome Sequencing of 47 MSI colorectal cancers (CRCs) and paired adjacent normal mucosa
Targeted gene sequencing of cancer driver genes to determine the driver mutations present in newly-derived cancer organoid models
Whole genome sequencing data on 10 human cancer cell lines
Fastq files of 239 samples of biliary tract cancer
268 samples with ALK-positiv non-small cell lung cancer, ultra-low coverage whole genome sequencing
Detection of SNVs/indels in the germline of pediatric cancer patients with a focus on CHEK2 germline variants.
Detection of SNVs/ indels in the germline of pediatric cancer patients with a focus on CHEK2 germline variants
Characterising the evolutionary dynamics of cancer proliferation in single-cell clones with SPRINTER
Geographic variation of mutagenic exposures in kidney cancer genomes – filtered vcf files (Mutographs)
Geographic variation of mutagenic exposures in kidney cancer genomes – patient metadata files (Mutographs)
Geographic variation of mutagenic exposures in kidney cancer genomes – copy number variants (Mutographs)
Geographic and age-related variations in mutational processes in colorectal cancer - sequence data (Mutographs)
