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• Clonal IGHV rearrangements in IGH+ and IGHUND HGBCL-DH-BCL2(-BCL6)

  PCR-based VDJ profiling in IGH+ and IGHUND HGBCL-DH-BCL2(-BCL6) lymphomas

  Dataset EGAD50000001523

• Targeted_NanoSeq___Thyroid

  Targeted NanoSeq in thyroid from a number of donors, both healthy and with pathology.

  Study EGAS00001007647

• WGS of 8 trios - affected child and both normal parents

  WGS of 8 trios - affected child and both normal parents

  Dataset EGAD00001001467

• RNA-Seq of human stimulated and cultured CD4+ Treg cells

  This dataset includes whole transcriptome data of human stimulated and cultured CD4+ Treg cells (39 samples).

  Dataset EGAD00001005964

• Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden

  Profiling of circulating tumor DNA (ctDNA) may offer a non-invasive approach to monitor disease progression. Here, we developed a quantitative method, exploiting local tissue-specific cell-free DNA (cfDNA) degradation patterns, that accurately estimates ctDNA burden independent of genomic aberrations. Nucleosome-dependent cfDNA degradation at promoters and first exon-intron junctions was strongly associated with differential transcriptional activity in tumors and blood. A quantitative model, based on just 6 regulatory regions, could accurately predict ctDNA levels in colorectal cancer patients. Strikingly, a model restricted to blood-specific regulatory regions could predict ctDNA levels across both colorectal and breast cancer patients.

  Study EGAS00001004657

• The Nordic Centre of Excellence Programme in Molecular Medicine Data Access Committee

  Dac EGAC00000000006

• Novel de novo pathogenic variant in the GNAI1 as a cause of severe disorders of intellectual development with autistic features

  Study EGAS00001005346

• A cycling, progenitor-like cell population at the root of atypical teratoid rhabdoid tumor subtype differentiation trajectories

  Study EGAS00001008123

• Novel de novo pathogenic variant in the GNAI1 as a cause of severe disorders of intellectual development with autistic features

  Study EGAS00001005355

• 500FG DNA methylation data

  This dataset contains the DNA methylation data of 260 samples from Dutch healthy individuals.

  Dataset EGAD00010002769