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• EGAD00010000474

  blood-based gene expression from breast cancer cases and age-matched controls in case-control serie 2 (CC2)

  Dataset EGAD00010000474

• EGAD00010000476

  blood-based gene expression from breast cancer cases and age-matched controls in case-control serie 1 (CC1)

  Dataset EGAD00010000476

• EGAD00010000478

  blood-based gene expression from breast cancer cases and age-matched controls in case-control serie 3 (CC3)

  Dataset EGAD00010000478

• Methylation differences in trisomy 21 using monozygotic twins - RRBS dataset

  Dataset EGAD00001001272

• Identification of molecular subgroups in multiple myeloma by whole exome sequencing.

  Dataset EGAD00001004408

• RHD_NC_OMNI_Cases

  Rheumatic heart disease cases recruited in New Caledonia with higher density genotyping

  Dataset EGAD00010000956

• Somatic mutations in healthy and leukemic blood progenitors reveal evolutionary mechanisms underlying childhood leukemia and differential patient outcome

  Study EGAS00001004593

• RNA sequencing of in vitro generated suppressive myeloid cells using parental and Sialidase expressing A549 cancer cell lines

  Study EGAS00001007618

• Genomic and immune signatures predict clinical outcome in newly diagnosed multiple myeloma treated with immunotherapy regimens

  Study EGAS00001007404

• Single cell RNA sequencing reveals induced bifurcated differentiation after RUNX1::RUNX1T1 depletion in patient-derived leukemic blasts

  Study EGAS00001008050

• Clonal evolution study of Intrahepatic cholangiocarcinoma in Zhongshan Hospital

  Clonal evolution study of Intrahepatic cholangiocarcinoma

  Study EGAS00001002625

• Cetuximab treatment of metastasis-derived organoids (LMO)

  Cetuximab treatment in organoids

  Dataset EGAD00001009404

• Whole Exome Sequencing in resected HCC

  35 paired samples ressected HCC

  Dataset EGAD00001006073

• Whole exome sequencing of preneoplasia lung adenocarcinoma

  Multi-region exome sequencing of 271 pulmonary nodules and matched adjacent lung tissue including lung preneoplasia atypical adenomatous hyperplasia (AAH, N=49), adenocarcinoma in situ (AIS, N=42), minimally invasive adenocarcinoma (MIA, N=37), invasive lung adenocarcinoma (ADC, N=57) and adjacent lung tissues (Normal, N=88).

  Study EGAS50000000270

• De novo modeling of chromoplectic Ewing sarcoma tumors from patient-derived mesenchymal stem cells

  Ewing sarcoma is characterized by pathognomonic translocations fusing most frequently EWSR1 with FLI1 (EF1). In addition, Ewing sarcoma can also display alterations in STAG2, TP53 and CDKN2A (SPC). Starting from Ewing sarcoma derived human mesenchymal stem cells (MSCpat), we recapitulated this translocation and SPC alterations using a CRISPR/cas9 approach and generated a bona fide Ewing sarcoma model (EWIma1) displaying transcriptomic (RNA-seq) and epigenetic (ChIP-seq) hallmarks of EwS.

  Dataset EGAD50000001673

• ATAC-seq and ChIP-seq analysis of patient-derived normal pancreas and pancreas neoplasm organoids

  Pancreatic cancers arise from two different precursors; intraductal papillary mucinous neoplasms (IPMN) and pancreatic intraepithelial neoplasm (PanIN), while biological differences in cancers originated from them remain obscure. Here, we analyzed their epigenomic landscape by ATAC-seq and ChIP-seq using patient-derived organoids.

  Study JGAS000264

• DKFZ-HIPO Project H021/NCT MASTER

  Clinical genome and transcriptome sequencing in younger adults with advanced-stage cancer across all histologies: DKFZ-HIPO Project H021 (http://www.hipo-heidelberg.org/hipo2/index.php/menu-item-2/32-021-prospective-genetic-characterization-of-tumors-from-individual-patients-of-special-interest) / NCT MASTER (http://www.nct-heidelberg.de/forschung/nct-master.html)

  Study EGAS00001000948

• CCTG IND.231 WGS DNA Sequencing Data

  41 WGS DNA sequences from: Phase I trial of CX-5461, a first-in-class G-quadruplex stabilizer in patients with advanced solid tumors enriched for DNA-repair deficiencies (CCTG IND.231)

  Dataset EGAD00001008756

• RNA-seq of PDAC patient-derived xenograft tumors

  This dataset contains single cell RNA-seq data of stromal cells derived from two PDX models (N = 2 in total) and bulk RNA-seq data of two PDX models treated with gemcitabine and our novel antibody-drug conjugate, C6-EBET (N = 59 in total). Bulk RNA-seq experiments were performed with Agilent SureSelect Strand Specific RNA Library Prep Kit (Agilent). Single cell RNA-seq experiments were performed with Chromium Single Cell 3' Reagent Kits v2 Chemistry (10x Genomics).

  Dataset EGAD00001010130

• Whole Exome Sequencing of healthy Spanish individuals

  The need for a detailed catalogue of local variability for the study of rare diseases within the context of the Medical Genome Project motivated the whole exome sequencing of 267 unrelated individuals, representative of the healthy Spanish population.

  Study EGAS00001000938

• EGAD00010000560

  SNP array of 7 HCCs and matched background liver in children with bile salt export pump deficiency

  Dataset EGAD00010000560

• Mutational landscape and clonal architecture in grade-II/III gliomas

  Dataset EGAD00001001213

• Targeted analysis of cell-free circulating tumor DNA is suitable for early relapse and actionable target detection in patients with neuroblastoma

  Study EGAS00001006027

• Multi-omics integration reveals only minor long-term molecular and functional sequelae in immune cells of individuals recovered from COVID-19

  Dac EGAC00001002267

• Liquid biopsy-based minimal residual disease monitoring for early risk stratification and decision-making in advanced non-small cell lung cancer

  Dac EGAC50000000832