Matched Pair Cancer Cell line Whole Genomes

Study ID Alternative Stable ID Type
EGAS00001000160 Cancer Genomics

Study Description

We propose to definitively characterise the somatic genetics of 29 matched pair cell lines through generation of comprehensive catalogues of somatic mutations by high coverage genome sequencing.

Study Datasets 3 datasets.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
Matched Pair Cancer Cell line Whole Genomes
Illumina HiSeq 2000 58
Insertion of processed pseudogenes is known to occur in the germline but has not previously been observed in somatic cells. Formation of pseudogenes could represent a new class of mutation in cancers and a new source of potential driver events.
Illumina HiSeq 2000 20
Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
Illumina HiSeq 2000 4

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