Study
SCAT osteosarcoma sequencing
Study ID | Alternative Stable ID | Type |
---|---|---|
EGAS00001000196 | Cancer Genomics |
Study Description
Agilent whole exome hybridisation capture will be performed on genomic DNA derived from 50 osteosarcoma cancers and matched normal DNA from the same patients. Three lanes of Illumina GA sequencing will be performed on the resulting 100 exome libraries and mapped to build 37 of the human reference genome to facilitate the identification of novel cancer genes
Study Datasets 3 datasets.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Dataset ID | Description | Technology | Samples |
---|---|---|---|
EGAD00001000107 |
SCAT osteosarcoma sequencing
|
Illumina Genome Analyzer II,Illumina HiSeq 2000 | 114 |
EGAD00001000280 |
This experiment is to validate putative somatic substitutions and indels identified in an exome screen of ~50 osteosarcoma tumour/normal pairs. It is the first stage in our ICGC commitment to study osteosarcoma. The validation process is an important component of our analysis to clarify the data prior to looking for evidence of new cancer genes, or subverted pathways important in the development of cancer. This data is part of a pre-publication release. For information on the proper use of ... (Show More)
|
Illumina HiSeq 2000 | 112 |
EGAD00001004201 |
Multiple signatures of somatic mutations have been identified in human cancer genomes. To investigate whether mutational signatures continue to be generated, and if so their temporal patterns of activity, subsets of cell lines were cultured in vitro for extended periods and subjected to single cell cloning and whole genome or exome sequencing or directly to single cell whole genome sequencing. As expected, signatures of past exogenous exposures, such as tobacco smoke and ultraviolet light, were ... (Show More)
|
Illumina HiSeq 2000,Illumina HiSeq 2500 | 75 |
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