Study
Whole Genome Sequencing of Neuroblastoma
| Study ID | Alternative Stable ID | Type |
|---|---|---|
| EGAS00001000222 | Whole Genome Sequencing |
Study Description
NA
Study Datasets 4 datasets.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
| Dataset ID | Description | Technology | Samples |
|---|---|---|---|
| EGAD00001000196 |
Neuroblastoma samples
|
Complete Genomics | 203 |
| EGAD00001000202 |
Neuroblastoma samples (Analyses_vcf files)
|
204 | |
| EGAD00001001360 |
The majority of neuroblastoma patients have tumors that initially respond to chemotherapy, but a large proportion of patients will experience therapy-resistant relapses. The molecular basis of this aggressive phenotype is unknown. Whole genome sequencing of 23 paired diagnostic and relapsed neuroblastomas showed clonal evolution from the diagnostic tumor with a median of 29 somatic mutations unique to the relapse sample. Eighteen of the 23 relapse tumors (78%) showed RAS-MAPK pathway mutations. ... (Show More)
|
221 | |
| EGAD00010000552 |
Neuroblastoma samples
|
130 |
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