Study

Whole Genome Sequencing of Neuroblastoma

Study ID Alternative Stable ID Type
EGAS00001000222 Whole Genome Sequencing

Study Description

NA

Study Datasets 4 datasets.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001000196
Neuroblastoma samples
Complete Genomics 203
EGAD00001000202
Neuroblastoma samples (Analyses_vcf files)
204
EGAD00001001360
The majority of neuroblastoma patients have tumors that initially respond to chemotherapy, but a large proportion of patients will experience therapy-resistant relapses. The molecular basis of this aggressive phenotype is unknown. Whole genome sequencing of 23 paired diagnostic and relapsed neuroblastomas showed clonal evolution from the diagnostic tumor with a median of 29 somatic mutations unique to the relapse sample. Eighteen of the 23 relapse tumors (78%) showed RAS-MAPK pathway mutations. ... (Show More)
221
EGAD00010000552
Neuroblastoma samples
130

Who archives the data?

There are no publications available