Genetic landscape of pediatric Infant Acute Lymphoblastic leukemia
We performed whole genome sequencing of tumor and normal DNA samples obtained from 22 infant ALL cases with MLL rearrangements. In addition, we sequenced 2 paired diagnostic-relapse samples. Using complementary pipelines, somatically acquired genetic changes were analyzed, including single nucleotide variations (SNVs), insertion/deletions, structural variations and copy number variations in the cancer genomes. In addition, exome sequencing was performed on paired diagnostic and normal DNA samples obtained from 20 cases of non-infant MLL rearranged leukemias and somatic mutations in the coding regions were identified.
- Type: Whole Genome Sequencing
- Archiver: EGA European Genome-Phenome Archive
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
|EGAD00001000165||Illumina HiSeq 2000||46|
|EGAD00001001098||Illumina HiSeq 2000||63|
|EGAD00001001245||Illumina HiSeq 2000||40|
|EGAD00001001432||Illumina HiSeq 2000||1337|
|EGAD00001001433||Illumina HiSeq 2000||906|
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