Study

Identification of mutations and structural rearrangements in plasma DNA form metastatic prostate cancer patients

Study ID Alternative Stable ID Type
EGAS00001000453 Resequencing

Study Description

NA

Study Datasets 2 datasets.

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Dataset ID Description Technology Samples
EGAD00001000364
We performed low coverage whole genome sequencing of plasma DNA from prostate cancer patients to establish copy number profiles on both a genome-wide and a gene-specific level. The data include plasma samples from prostate cacner patients (n=13), non-malignant controls (males, n=10 and females, n=9), plasma samples from pregnancies with aneuploid and euploid fetuses (n=4). Furthermore, we sequenced different tumor samples (n=6) of one patients and a serial dilution of HT29 in a background of ... (Show More)
Illumina MiSeq 50
EGAD00001000365
In this study we analysed patients with metastatic prostate cancer to scan their tumor genomes noninvasively in plasma DNA. We enriched 1.3 Mbp of seven plasma DNAs (4 CRPC cases: CRPC1-3 and CRPC5; 3 CSPC cases: CSPC1-2 and CSPC4) including exonic sequences of 55 cancer genes and 38 introns of 18 genes, where fusion breakpoints have been described using Sure Select Custom DNA Kit.
Illumina MiSeq 7

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