Study
Identification of mutations and structural rearrangements in plasma DNA form metastatic prostate cancer patients
Study ID | Alternative Stable ID | Type |
---|---|---|
EGAS00001000453 | Resequencing |
Study Description
NA
Study Datasets 2 datasets.
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Dataset ID | Description | Technology | Samples |
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EGAD00001000364 |
We performed low coverage whole genome sequencing of plasma DNA from prostate cancer patients to establish copy number profiles on both a genome-wide and a gene-specific level. The data include plasma samples from prostate cacner patients (n=13), non-malignant controls (males, n=10 and females, n=9), plasma samples from pregnancies with aneuploid and euploid fetuses (n=4). Furthermore, we sequenced different tumor samples (n=6) of one patients and a serial dilution of HT29 in a background of ... (Show More)
|
Illumina MiSeq | 50 |
EGAD00001000365 |
In this study we analysed patients with metastatic prostate cancer to scan their tumor genomes noninvasively in plasma DNA. We enriched 1.3 Mbp of seven plasma DNAs (4 CRPC cases: CRPC1-3 and CRPC5; 3 CSPC cases: CSPC1-2 and CSPC4) including exonic sequences of 55 cancer genes and 38 introns of 18 genes, where fusion breakpoints have been described using Sure Select Custom DNA Kit.
|
Illumina MiSeq | 7 |
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