Use of Deep Sequencing to Dectect Clonal Mutations In Sun Exposed Skin Epidermis
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
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This study aims to define the landscape of somatic mutations in sun exposed human skin by deep sequencing, analyse their frequency and use the data to infer the effect of mutations on proliferating cell behaviour. The frequency of each mutation will reflect the size of the clone of cells in the tissue sample. By analyzing small samples, clones with as few as 100 cells will be detectable. Allele frequency distributions for each mutation will be used to infer cell fate using published methods ... (Show More)
|Illumina HiSeq 2000||166|