Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing.
Proc Natl Acad Sci U S A
110:
2013
18761-18768
|
226
|
CancerDetector: ultrasensitive and non-invasive cancer detection at the resolution of individual reads using cell-free DNA methylation sequencing data.
Nucleic Acids Res
46:
2018
e89
|
96
|
Leveraging locus-specific epigenetic heterogeneity to improve the performance of blood-based DNA methylation biomarkers.
Clin Epigenetics
12:
2020
154
|
6
|
DISMIR: Deep learning-based noninvasive cancer detection by integrating DNA sequence and methylation information of individual cell-free DNA reads.
Brief Bioinform
22:
2021
bbab250
|
21
|
Cost-effective methylome sequencing of cell-free DNA for accurately detecting and locating cancer.
Nat Commun
13:
2022
5566
|
28
|
Epigenetic analysis of cell-free DNA by fragmentomic profiling.
Proc Natl Acad Sci U S A
119:
2022
e2209852119
|
29
|
Comprehensive tissue deconvolution of cell-free DNA by deep learning for disease diagnosis and monitoring.
Proc Natl Acad Sci U S A
120:
2023
e2305236120
|
10
|