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Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing

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Policy for Plasma DNA data sharing

The CUHK Circulating Nucleic Acids Research Group Data Access Agreement This agreement governs the terms and conditions on which access will be granted to users of the sequencing and genotyping data generated by The Chinese University of Hong Kong (CUHK) Circulating Nucleic Acids Research Group (CNARG). The terms and conditions of access set out in this agreement apply both to the User and the User’s Institution (both as defined below). User is referred to within the agreement as “You” and the term “Your” will be construed accordingly. By signing this agreement, You agree to be bound by the terms and conditions of access set out in this agreement. Definitions: Group means The Chinese University of Hong Kong (CUHK) Circulating Nucleic Acids Research Group (CNARG). Data means all and any human genetic data obtained by User or User’s Institution from the Group via the European Genome-phenome Archive. Data Subject means a person, who has been informed of the purpose for which the Data is held and has given his/her informed consent thereto. In the event that the Data Subject is legally incapable of giving an informed consent, such consent has been given by his/her legal guardian. User means a researcher whose User’s Institution has previously completed this Data Access Agreement and has received acknowledgement of its acceptance by the Group. Data Access Committee means a committee assigned by the Group for reviewing and approving the data access application of the User. The committee consists of three or more investigators from the Group. Publications means, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written, electronic, graphical, photographic, recorded (including oral recordings), and verbal presentations of research. User’s Institution means the organisation at which the User is employed, affiliated or enrolled. Terms and Conditions: By signing this agreement: 1. You agree to use the Data only for the advancement of medical and scientific research, according to the consent given by Data Subjects. 2. You agree not to use the Data for the creation of products for sale or for any commercial purpose. 3. You agree to preserve, at all times, the confidentiality of information and Data pertaining to Data Subjects. In particular, You undertake not to use, or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy. 4. You agree not to transfer or disclose the Data, in whole or in part, or any information/material derived from the Data, to others, except as reasonably necessary for data/safety monitoring or programme management. Should You wish to share the Data with a collaborator within the same User’s Institution, the collaborator must make a separate application for access to the Data. 5. You agree to use the Data for the approved purpose and project described in your application only; use of the Data for a new purpose or project will require a new application and approval. 6. You agree to acknowledge in any work based in whole or in part on the Data, the publications from which the Data derives, the version of the Data, and the role of the Group. The wordings of the acknowledgement are “This study makes use of data generated by The Chinese University of Hong Kong (CUHK) Circulating Nucleic Acids Research Group, as reported by Chan et al in Clinical Chemistry (doi:10.1373/clinchem.2012.196014). 7. You accept that the Group, the original data creators, depositors or copyright holders, or the funders of the Group: a) make no warranties or representations with respect to the Data, including but not limited to its fitness for purpose, accuracy or comprehensiveness, the continued access to the Data without interruption; and b) accept no liability for any direct, indirect, consequential, special or incidental, damages or losses arising from or in connection with the use of the Data or this agreement. 8. You understand and acknowledge that the Data is protected by copyright and other intellectual property rights, and that reproduction, except as reasonably required to carry out Your research with the Data in accordance with the approved purpose referred to in paragraph 5 above, or sale of all or part of the Data in any form is not permitted. 9. You agree that nothing in this agreement shall operate to transfer to You or to the User’s Institution any intellectual property rights relating to the Data. 10. You accept that this agreement will be terminated immediately by the Group without notice upon breach of any terms of this agreement by You and You agree to destroy any Data held when required. 11. You accept that it may be necessary for the Group or its appointed agent to alter the terms of this agreement from time to time in order to address new concerns. In this event, the Group or its appointed agent will to inform You of any changes. You agree that Your continued use of the Data shall be deemed to represent your consent to any revised terms of the Agreement. 12. You agree that you will submit a report to the Data Access Committee, if requested, on completion of the agreed purpose. The Data Access Committee agrees to treat the report and all information, data, results, and conclusions contained within such report as confidential information belonging to the User’s Institution. 13. You accept that the Data is protected by the privacy law in the relevant jurisdiction and that You are responsible for ensuring Your use of the Data is in compliance with any such applicable law. Notwithstanding the above, nothing in this agreement shall limit the rights of the Data Subjects under the Personal Data (Privacy) Ordinance (Cap 486) in Hong Kong. The Data Access Committee reserves the right to request and inspect data security and management documentation to ensure the adequacy of data protection measures in countries that have no national laws comparable to that which pertain in the Personal Data (Privacy) Ordinance in Hong Kong. 14. This agreement shall be construed, interpreted and governed by the laws of Hong Kong Special Administrative Region.   For and on behalf of User: Name of Applicant(s): _____________________________________ _____________________________________ _____________________________________ _____________________________________ Signature of Applicant(s): _____________________________________ _____________________________________ _____________________________________ _____________________________________ Date: _____________________________________ For and on behalf of User’s Institution: Signature of Institutional or Administrative Authority: ______________________________________ Print name: ______________________________________ User’s Institution: ______________________________________ Date: ¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬______________________________________ WHEN SUBMITTING THIS DOCUMENT, PLEASE INCLUDE ALL PAGES OF THE AGREEMENT WITH THIS SIGNATURE PAGE

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001000566 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00000286231 fq.bz2 11.9 GB
EGAF00000286232 fq.bz2 12.2 GB
EGAF00000286233 fq.bz2 8.1 GB
EGAF00000286234 fq.bz2 8.8 GB
EGAF00000286235 fq.bz2 7.9 GB
EGAF00000286236 fq.bz2 7.3 GB
EGAF00000286237 fq.bz2 7.3 GB
EGAF00000286238 fq.bz2 10.2 GB
EGAF00000286239 fq.bz2 6.6 GB
EGAF00000286240 fq.bz2 6.7 GB
EGAF00000286241 fq.bz2 7.2 GB
EGAF00000286242 fq.bz2 3.3 GB
EGAF00000286243 fq.bz2 4.9 GB
EGAF00000286244 fq.bz2 3.4 GB
EGAF00000286245 fq.bz2 4.7 GB
EGAF00000286246 fq.bz2 8.6 GB
EGAF00000286247 fq.bz2 3.5 GB
EGAF00000286248 fq.bz2 5.3 GB
EGAF00000286249 fq.bz2 4.9 GB
EGAF00000286250 fq.bz2 9.9 GB
EGAF00000286251 fq.bz2 10.2 GB
EGAF00000286252 fq.bz2 10.4 GB
EGAF00000286253 fq.bz2 9.4 GB
EGAF00000286254 fq.bz2 6.7 GB
EGAF00000286255 fq.bz2 8.8 GB
EGAF00000286256 fq.bz2 9.2 GB
EGAF00000286257 fq.bz2 6.5 GB
EGAF00000286258 fq.bz2 13.5 GB
EGAF00000286259 fq.bz2 13.5 GB
EGAF00000286260 fq.bz2 11.0 GB
EGAF00000286261 fq.bz2 12.9 GB
EGAF00000286262 fq.bz2 11.7 GB
EGAF00000286263 fq.bz2 6.8 GB
EGAF00000286264 fq.bz2 6.3 GB
EGAF00000286265 fq.bz2 8.1 GB
EGAF00000286266 fq.bz2 7.1 GB
EGAF00000286267 fq.bz2 6.6 GB
EGAF00000286268 fq.bz2 6.0 GB
EGAF00000286269 fq.bz2 7.3 GB
EGAF00000286270 fq.bz2 7.1 GB
EGAF00000286271 fq.bz2 6.8 GB
EGAF00000286272 fq.bz2 7.1 GB
EGAF00000286273 fq.bz2 8.1 GB
EGAF00000286274 fq.bz2 7.3 GB
EGAF00000286275 fq.bz2 6.6 GB
EGAF00000286276 fq.bz2 6.0 GB
EGAF00000286277 fq.bz2 6.3 GB
EGAF00000286278 fq.bz2 7.1 GB
EGAF00000286279 fq.bz2 8.1 GB
EGAF00000286280 fq.bz2 7.4 GB
EGAF00000286281 fq.bz2 9.8 GB
EGAF00000286282 fq.bz2 7.6 GB
EGAF00000286283 fq.bz2 9.6 GB
EGAF00000286284 fq.bz2 8.5 GB
EGAF00000286285 fq.bz2 8.4 GB
EGAF00000286286 fq.bz2 11.3 GB
EGAF00000286287 fq.bz2 8.6 GB
EGAF00000286288 fq.bz2 8.2 GB
EGAF00000286289 fq.bz2 7.6 GB
EGAF00000286290 fq.bz2 7.8 GB
EGAF00000286291 fq.bz2 7.9 GB
EGAF00000286292 fq.bz2 8.1 GB
EGAF00000286293 fq.bz2 6.0 GB
EGAF00000286294 fq.bz2 6.1 GB
EGAF00000286295 fq.bz2 8.9 GB
EGAF00000286296 fq.bz2 10.0 GB
EGAF00000286297 fq.bz2 7.0 GB
EGAF00000286298 fq.bz2 7.3 GB
EGAF00000286299 fq.bz2 9.2 GB
EGAF00000286300 fq.bz2 9.6 GB
EGAF00000286301 fq.bz2 6.5 GB
EGAF00000286302 fq.bz2 9.5 GB
EGAF00000286303 fq.bz2 4.1 GB
EGAF00000286304 fq.bz2 4.0 GB
EGAF00000286305 fq.bz2 3.3 GB
EGAF00000286306 fq.bz2 3.6 GB
EGAF00000286307 fq.bz2 3.5 GB
EGAF00000286308 fq.bz2 10.7 GB
EGAF00000286309 fq.bz2 10.5 GB
EGAF00000286310 fq.bz2 2.5 GB
EGAF00000286311 fq.bz2 3.6 GB
EGAF00000286312 fq.bz2 2.3 GB
EGAF00000286313 fq.bz2 10.8 GB
EGAF00000286314 fq.bz2 8.8 GB
EGAF00000286315 fq.bz2 10.2 GB
EGAF00000286316 fq.bz2 10.4 GB
EGAF00000286317 fq.bz2 9.5 GB
EGAF00000286318 fq.bz2 8.9 GB
EGAF00000286319 fq.bz2 8.7 GB
EGAF00000286320 fq.bz2 10.5 GB
EGAF00000286321 fq.bz2 10.0 GB
EGAF00000286322 fq.bz2 8.9 GB
EGAF00000286323 fq.bz2 10.4 GB
EGAF00000286324 fq.bz2 4.8 GB
EGAF00000286325 fq.bz2 4.0 GB
EGAF00000286326 fq.bz2 5.7 GB
EGAF00000286327 fq.bz2 8.4 GB
EGAF00000286328 fq.bz2 10.9 GB
EGAF00000286329 fq.bz2 10.2 GB
EGAF00000286330 fq.bz2 10.4 GB
100 Files (786.0 GB)