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HipSci-RNAseq-healthy volunteers

The HipSci project brings together diverse constituents in genomics, proteomics, cell biology and clinical genetics to create a UK national iPS cell resource and use it to carry out cellular genetic studies. In this sup-study we perform RNAseq on iPS cells generated from skin biopsies from healthy volunteers.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001000897 Illumina HiSeq 2000 22
EGAD00001001438 Illumina HiSeq 2000 116
EGAD00001001933 Illumina HiSeq 2000 118
EGAD00001003529 Illumina HiSeq 2000 Illumina HiSeq 2500 118
Publications Citations
Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression.
Nat Commun 11: 2020 810
Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation.
Nat Genet 53: 2021 304-312
Optimizing expression quantitative trait locus mapping workflows for single-cell studies.
Genome Biol 22: 2021 188
Cell reprogramming shapes the mitochondrial DNA landscape.
Nat Commun 12: 2021 5241
A compendium of uniformly processed human gene expression and splicing quantitative trait loci.
Nat Genet 53: 2021 1290-1299