Study
ICGC Oesophageal adenocarcinoma - 100 tumour samples
| Study ID | Alternative Stable ID | Type |
|---|---|---|
| EGAS00001000724 | Other |
Study Description
The oesophageal project will focus on adenocarcinoma which is increasing in incidence in the UK and other developed countries and has a very poor outcome. The primary aims of this project are to deeply sequence tumour and normal genomic DNA (including the precursor condition Barrett’s oesophagus when material is available) to provide a comprehensive catalogue of somatic mutations. This will be achieved through a UK-wide network of hospitals involved in a research collaboration called the OCCAMS consortium. The goal of this project is to use high quality clinical material with accurately annotated clinic-pathological, treatment and outcome data.
Study Datasets 16 datasets.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
| Dataset ID | Description | Technology | Samples |
|---|---|---|---|
| EGAD00001001048 |
Samples from Edwards et al 2015 - doi:10.1186/s12864-015-1685-z
|
Illumina HiSeq 2000 | 86 |
| EGAD00001001071 |
Samples from the "100" project that are in the ICGC PanCancer project.
|
Illumina HiSeq 2000 | 200 |
| EGAD00001001394 |
Samples from Ross Innes et. al 2015 - doi:10.1038/ng.3357
|
Illumina HiSeq 2000 | 101 |
| EGAD00001001457 |
All samples from the "100" project
|
Illumina HiSeq 2000 | 238 |
| EGAD00001001960 |
upcoming publication
|
Illumina HiSeq 2000 | 171 |
| EGAD00001002218 |
Sequencing data for ICGC Oesophageal Adenocarcinoma tissue samples - 129_cohort
EAC whole genomic sequencing data - Publication Secrier & Li et al., 2016, Nature Genetics
|
Illumina HiSeq 2000 | 258 |
| EGAD00001002241 |
Sequencing data for ICGC Oesophageal Adenocarcinoma tissue samples - chemo_cohort
|
Illumina HiSeq 2000 | 270 |
| EGAD00001002689 |
ICGC Oesophageal Adenocarcinoma tissue samples
|
Illumina HiSeq 2000 | 10 |
| EGAD00001003292 |
WGS sequencing for cases from the ICGC ESAD-UK project
Tumours 50x Normals 30x
HiSeq X
BAM files
These samples are all available in ICGC release 24
|
Illumina HiSeq 2000 | 520 |
| EGAD00001003580 |
WGS sequencing for 303 cases (620 samples) from the ICGC ESAD-UK project
Tumours 50x Normals 30x
HiSeq X
BAM files
These samples are all available in ICGC release 26
|
Illumina HiSeq 2000 | 620 |
| EGAD00001004137 |
WGS sequencing for 409 cases (832 samples) from the ICGC ESAD-UK project
Tumours 50x Normals 30x
HiSeq X
BAM files
These samples are all available in ICGC release 28
|
Illumina HiSeq 2000 | 832 |
| EGAD00001004417 |
Data supporting: "The landscape of selection in 551 Esophageal Adenocarcinomas defines genomic biomarkers for the clinic." Frankell et al.
WGS (BAM files)
379 matched tumour-normal pairs
|
Illumina HiSeq 2000 | 758 |
| EGAD00001004775 |
Data supporting: "Patient-specific detection of cancer genes reveals recurrently perturbed processes in esophageal adenocarcinoma." Mourikis et al.
WGS (BAM files)
521 samples
|
Illumina HiSeq 2000 | 521 |
| EGAD00001005434 |
Data supporting: "Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma." Noorani et al.
WGS (BAM files)
134 samples for 18 cases
Includes primary, lymph-node, distant metastatic, Barrett's and normal samples.
|
Illumina HiSeq 2000 | 134 |
| EGAD00001007493 |
Data supporting: "Genomic analysis of response to neoadjuvant chemotherapy in esophageal adenocarcinoma" Izadi et al.
WGS for tumour and normal samples.
RNAseq for tumour samples.
|
HiSeq X Five,Illumina HiSeq 2000,Illumina NovaSeq 6000 | 160 |
| EGAD00001007496 |
Data supporting: "Widespread reorganisation of the regulatory chromatin landscape facilitates resistance to inhibition of oncogenic ERBB2 signalling" Ogden et al.
WGS for tumour and normal samples.
RNAseq for tumour samples.
|
HiSeq X Five,Illumina HiSeq 2000 | 636 |
Who archives the data?
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