Study

Whole genome and RNA sequencing of paediatric glioblastoma in the ICGC PedBrain project

Study ID Alternative Stable ID Type
EGAS00001001139 Other

Study Description

Paediatric glioblastoma (pedGBM) is characterised by substantial intertumoural heterogeneity. In order to identify the genetic lesions underlying tumourigenesis, we analysed whole genomes and transcriptomes of pedGBMs and in vitro model systems by next generation sequencing. Novel fusions of the receptor tyrosine kinase MET lead us to investigate targeted therapy using MET inhibitors. This study is part of the International Cancer Genome Consortium PedBrain Tumor Project (ICGC PedBrain, http://www.pedbraintumor.org/).

Study Datasets 2 datasets.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001001944
RNA sequencing of paediatric glioblastoma in the ICGC PedBrain project
Illumina HiSeq 2500 42
EGAD00001002006
Whole genome sequencing of paediatric glioblastoma in the ICGC PedBrain project
Illumina HiSeq 2500 115

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Publications

Citations

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