Clonal architecture of pre malignant and malignant tumours
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
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That tobacco smoking causes lung cancer is well-established, but we lack quantitative understanding of its effects on genomes of normal bronchial epithelium. We sequenced whole genomes of 632 colonies derived from single bronchial epithelial cells across 16 subjects. Tobacco smoking is the major influence on mutation burden, adding 1000-10,000+ mutations/cell, massively increasing both between-subject and within-subject variance, and generating several distinct signatures of substitutions and ... (Show More)
|HiSeq X Ten||644|