QSEA – modelling of genome-wide DNA methylation from sequencing enrichment experiments

Study ID Alternative Stable ID Type
EGAS00001001822 Other

Study Description

We describe a new method, QSEA, for analyzing methylation enrichment data. We generated a benchmark experiment consisting of MeDIP-seq enrichment data, targeted BS-seq validation data, and RNA-seq data on five pairs of tumor and adjacent normal samples of non-small cell lung cancer patients. Details of the method and its performance on the data have been described in Lienhard et al. (2016).

Study Datasets 1 dataset.

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Dataset ID Description Technology Samples
Benchmark data set containing five tumor/normal pairs of non-small cell lung cancer (NSCLC) patients. Tissue pairs were screened with bisulfite (BS) sequencing, MeDIP methylation enrichment sequencing and RNA sequencing in order to identify differentially methylated and expressed spots in the genomes.
Illumina HiSeq 2500 10

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