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Exome sequencing of United Kingdom Brain Expression Consortium samples

The United Kingdom Brain Expression Consortium studies regulation of gene expression through common and rare variation. One of the main set of samples is compound by bulk brain tissue from 10 brain regions obtained from 134 controls.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001003100 Illumina HiSeq 2000 65
Publications Citations
Genetic variability in the regulation of gene expression in ten regions of the human brain.
Nat Neurosci 17: 2014 1418-1428
425
Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing.
Genome Biol 18: 2017 22
65
Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information.
Nat Commun 11: 2020 1041
17
Assessing the relationship between monoallelic PRKN mutations and Parkinson's risk.
Hum Mol Genet 30: 2021 78-86
33
Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at 16q11.2 and MAPT H1 loci.
Brain 145: 2022 4349-4367
23
eQTL Catalogue 2023: New datasets, X chromosome QTLs, and improved detection and visualisation of transcript-level QTLs.
PLoS Genet 19: 2023 e1010932
3