Somatic mutation in skin epidermis SMS
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
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The risk of getting non-melanoma skin cancer varies over 40-fold across the body. Here we map mutations in normal skin in high and low risk sites in normal donors and those with an increased risk of skin cancer. The density of mutations varied widely, with evidence of positive and negative genetic selection. Regional differences in mutational signatures in high and low cancer risk sites and preferential selection of mutants of TP53 in high risk skin and FAT1 in lower risk skin were observed. ... (Show More)
|HiSeq X Ten,Illumina HiSeq 2500,Illumina NovaSeq 6000||805|