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Competitive selection of somatic mutant clones in normal human skin varies with body site

The risk of getting non-melanoma skin cancer varies over 40-fold across the body. Here we map mutations in normal skin in high and low risk sites in normal donors and those with an increased risk of skin cancer. The density of mutations varied widely, with evidence of positive and negative genetic selection.  Regional differences in mutational signatures in high and low cancer risk sites and preferential selection of mutants of TP53 in high risk skin and FAT1 in lower risk skin were observed. 10% of clones had copy number changes in cancer associated genes and the largest had multiple driver mutations with loss of heterozygosity. In hair follicles, a proposed site of origin of skin cancers, mutations in the upper follicle resembled adjacent skin, but the lower follicle was sparsely mutated. We conclude cancer risk reflects the efficiency of transformation of oncogenic mutants rather than the density of mutant clones.

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Wellcome Trust Sanger Institute Cancer Genome Group Data Sharing Policy

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001001933 Other
EGAS00001002165 Other
EGAS00001002416 Cancer Genomics
EGAS00001002708 Other
EGAS00001004462 Cancer Genomics
EGAS00001004463 Cancer Genomics
EGAS00001004464 Cancer Genomics
EGAS00001004465 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00001792928 cram 705.9 MB
EGAF00001792929 cram 683.1 MB
EGAF00001792930 cram 587.6 MB
EGAF00001792931 cram 666.6 MB
EGAF00001792932 cram 723.4 MB
EGAF00001792933 cram 855.5 MB
EGAF00001792934 cram 767.4 MB
EGAF00001792935 cram 762.6 MB
EGAF00001792936 cram 659.2 MB
EGAF00001792937 cram 655.3 MB
EGAF00001792938 cram 621.0 MB
EGAF00001792939 cram 674.5 MB
EGAF00001792940 cram 773.2 MB
EGAF00001792941 cram 804.0 MB
EGAF00001792942 cram 763.3 MB
EGAF00001792943 cram 773.4 MB
EGAF00001792944 cram 783.3 MB
EGAF00001792945 cram 747.0 MB
EGAF00001792946 cram 752.8 MB
EGAF00001792947 cram 795.3 MB
EGAF00001792948 cram 799.7 MB
EGAF00001792949 cram 929.0 MB
EGAF00001792950 cram 829.2 MB
EGAF00001792951 cram 848.6 MB
EGAF00001792952 cram 842.2 MB
EGAF00001792953 cram 761.5 MB
EGAF00001792954 cram 722.8 MB
EGAF00001793050 cram 632.2 MB
EGAF00001793051 cram 657.4 MB
EGAF00001793052 cram 702.7 MB
EGAF00001793053 cram 772.1 MB
EGAF00001793054 cram 766.2 MB
EGAF00001793055 cram 765.0 MB
EGAF00001793056 cram 712.4 MB
EGAF00001793057 cram 719.5 MB
EGAF00001793058 cram 728.4 MB
EGAF00001793059 cram 702.4 MB
EGAF00001793060 cram 714.6 MB
EGAF00001793061 cram 774.3 MB
EGAF00001793062 cram 744.1 MB
EGAF00001793063 cram 659.6 MB
EGAF00001793064 cram 783.0 MB
EGAF00001793065 cram 754.2 MB
EGAF00001793066 cram 723.2 MB
EGAF00001793067 cram 732.3 MB
EGAF00001793068 cram 746.7 MB
EGAF00001793069 cram 774.3 MB
EGAF00001793070 cram 743.8 MB
EGAF00001793071 cram 755.4 MB
EGAF00001793072 cram 676.4 MB
EGAF00001793073 cram 710.7 MB
EGAF00001793074 cram 643.1 MB
EGAF00002024960 cram 708.4 MB
EGAF00002025234 cram 891.0 MB
EGAF00002025476 cram 9.0 GB
EGAF00002025477 cram 6.4 GB
EGAF00002025564 cram 9.1 GB
EGAF00002025565 cram 6.4 GB
EGAF00002025568 cram 9.1 GB
EGAF00002025569 cram 6.5 GB
EGAF00002025572 cram 9.2 GB
EGAF00002025573 cram 6.5 GB
EGAF00003949817 cram 714.6 MB
EGAF00003949818 cram 708.0 MB
EGAF00003949819 cram 674.0 MB
EGAF00003949820 cram 670.2 MB
EGAF00003949821 cram 657.4 MB
EGAF00003949822 cram 600.6 MB
EGAF00003949823 cram 637.8 MB
EGAF00003949824 cram 683.0 MB
EGAF00003949825 cram 673.7 MB
EGAF00003949826 cram 773.0 MB
EGAF00003949827 cram 701.7 MB
EGAF00003949828 cram 935.5 MB
EGAF00003949829 cram 1.1 GB
EGAF00003949830 cram 981.9 MB
EGAF00003949831 cram 983.8 MB
EGAF00003949832 cram 1.0 GB
EGAF00003949833 cram 976.2 MB
EGAF00003949834 cram 1.0 GB
EGAF00003949835 cram 937.3 MB
EGAF00003949836 cram 987.0 MB
EGAF00003949837 cram 1.1 GB
EGAF00003949838 cram 1.0 GB
EGAF00003949839 cram 952.1 MB
EGAF00003949840 cram 992.1 MB
EGAF00003949841 cram 666.3 MB
EGAF00003949842 cram 646.6 MB
EGAF00003949843 cram 628.8 MB
EGAF00003949844 cram 634.0 MB
EGAF00003949845 cram 610.8 MB
EGAF00003949846 cram 654.1 MB
EGAF00003949847 cram 625.3 MB
EGAF00003949848 cram 580.5 MB
EGAF00003949849 cram 574.4 MB
EGAF00003949850 cram 658.8 MB
EGAF00003949851 cram 662.7 MB
EGAF00003949852 cram 614.6 MB
EGAF00003949853 cram 659.6 MB
EGAF00003949854 cram 610.0 MB
EGAF00003949855 cram 617.6 MB
EGAF00003949856 cram 602.7 MB
EGAF00003949857 cram 599.7 MB
EGAF00003949858 cram 685.7 MB
EGAF00003949859 cram 594.3 MB
EGAF00003949860 cram 638.4 MB
EGAF00003949861 cram 577.5 MB
EGAF00003949862 cram 599.3 MB
EGAF00003949863 cram 606.0 MB
EGAF00003949864 cram 598.7 MB
EGAF00003949865 cram 668.6 MB
EGAF00003949866 cram 634.3 MB
EGAF00003949867 cram 636.5 MB
EGAF00003949868 cram 612.4 MB
EGAF00003949869 cram 603.6 MB
EGAF00003949870 cram 580.4 MB
EGAF00003949871 cram 579.8 MB
EGAF00003949872 cram 625.7 MB
EGAF00003949873 cram 603.7 MB
EGAF00003949874 cram 648.7 MB
EGAF00003949875 cram 600.0 MB
EGAF00003949876 cram 644.9 MB
EGAF00003949877 cram 602.8 MB
EGAF00003949878 cram 620.4 MB
EGAF00003949879 cram 613.1 MB
EGAF00003949880 cram 603.2 MB
EGAF00003949881 cram 658.4 MB
EGAF00003949882 cram 685.2 MB
EGAF00003949883 cram 635.2 MB
EGAF00003949884 cram 679.3 MB
EGAF00003949885 cram 641.9 MB
EGAF00003949886 cram 604.0 MB
EGAF00003949887 cram 626.3 MB
EGAF00003949888 cram 604.4 MB
EGAF00003949889 cram 615.6 MB
EGAF00003949890 cram 669.8 MB
EGAF00003949891 cram 674.3 MB
EGAF00003949892 cram 628.5 MB
EGAF00003949893 cram 653.0 MB
EGAF00003949894 cram 642.9 MB
EGAF00003949895 cram 641.7 MB
EGAF00003949896 cram 618.4 MB
EGAF00003949897 cram 623.6 MB
EGAF00003949898 cram 573.4 MB
EGAF00003949899 cram 590.8 MB
EGAF00003949900 cram 604.4 MB
EGAF00003949901 cram 602.1 MB
EGAF00003949902 cram 612.0 MB
EGAF00003949903 cram 594.8 MB
EGAF00003949904 cram 589.8 MB
EGAF00003949905 cram 614.1 MB
EGAF00003949906 cram 621.3 MB
EGAF00003949907 cram 626.6 MB
EGAF00003949908 cram 625.6 MB
EGAF00003949909 cram 689.4 MB
EGAF00003949910 cram 627.7 MB
EGAF00003949911 cram 581.7 MB
EGAF00003949912 cram 619.6 MB
EGAF00003949913 cram 673.6 MB
EGAF00003949914 cram 577.5 MB
EGAF00003949915 cram 643.7 MB
EGAF00003949916 cram 648.9 MB
EGAF00003949917 cram 622.8 MB
EGAF00003949918 cram 645.5 MB
EGAF00003949919 cram 599.5 MB
EGAF00003949920 cram 625.5 MB
EGAF00003949921 cram 634.4 MB
EGAF00003949922 cram 670.1 MB
EGAF00003949923 cram 672.0 MB
EGAF00003949924 cram 632.0 MB
EGAF00003949925 cram 1.1 GB
EGAF00003949926 cram 1.1 GB
EGAF00003949927 cram 51.3 MB
EGAF00003949928 cram 1.1 GB
EGAF00003949929 cram 949.4 MB
EGAF00003949930 cram 938.1 MB
EGAF00003949931 cram 924.7 MB
EGAF00003949932 cram 994.5 MB
EGAF00003949933 cram 1.1 GB
EGAF00003949934 cram 1.1 GB
EGAF00003949935 cram 926.7 MB
EGAF00003949936 cram 919.8 MB
EGAF00003949937 cram 937.1 MB
EGAF00003949938 cram 961.7 MB
EGAF00003949939 cram 894.7 MB
EGAF00003949940 cram 837.6 MB
EGAF00003949941 cram 863.4 MB
EGAF00003949942 cram 801.5 MB
EGAF00003949943 cram 856.7 MB
EGAF00003949944 cram 797.7 MB
EGAF00003949945 cram 913.8 MB
EGAF00003949946 cram 925.5 MB
EGAF00003949947 cram 896.1 MB
EGAF00003949948 cram 1.1 GB
EGAF00003949949 cram 1.1 GB
EGAF00003949950 cram 1.3 GB
EGAF00003949951 cram 1.1 GB
EGAF00003949952 cram 1.2 GB
EGAF00003949953 cram 1.1 GB
EGAF00003949954 cram 1.0 GB
EGAF00003949955 cram 219.4 MB
EGAF00003949956 cram 1.1 GB
EGAF00003949957 cram 909.2 MB
EGAF00003949958 cram 1.1 GB
EGAF00003949959 cram 819.2 MB
EGAF00003949960 cram 852.4 MB
EGAF00003949961 cram 840.0 MB
EGAF00003949962 cram 912.3 MB
EGAF00003949963 cram 916.0 MB
EGAF00003949964 cram 965.5 MB
EGAF00003949965 cram 1.0 GB
EGAF00003949966 cram 916.8 MB
EGAF00003949967 cram 1.0 GB
EGAF00003949968 cram 877.1 MB
EGAF00003949969 cram 996.0 MB
EGAF00003949970 cram 843.5 MB
EGAF00003949971 cram 882.2 MB
EGAF00003949972 cram 940.9 MB
EGAF00003949973 cram 914.6 MB
EGAF00003949974 cram 867.4 MB
EGAF00003949975 cram 927.6 MB
EGAF00003949976 cram 874.8 MB
EGAF00003949977 cram 840.4 MB
EGAF00003949978 cram 911.4 MB
EGAF00003949979 cram 911.4 MB
EGAF00003949980 cram 916.0 MB
EGAF00003949981 cram 859.6 MB
EGAF00003949982 cram 882.7 MB
EGAF00003949983 cram 923.6 MB
EGAF00003949984 cram 850.8 MB
EGAF00003949985 cram 853.6 MB
EGAF00003949986 cram 659.6 MB
EGAF00003949987 cram 665.2 MB
EGAF00003949988 cram 755.8 MB
EGAF00003949989 cram 757.9 MB
EGAF00003949990 cram 750.9 MB
EGAF00003949991 cram 811.5 MB
EGAF00003949992 cram 668.6 MB
EGAF00003949993 cram 692.7 MB
EGAF00003949994 cram 689.7 MB
EGAF00003949995 cram 683.8 MB
EGAF00003949996 cram 769.4 MB
EGAF00003949997 cram 757.2 MB
EGAF00003949998 cram 751.4 MB
EGAF00003949999 cram 768.2 MB
EGAF00003950000 cram 611.2 MB
EGAF00003950001 cram 637.2 MB
EGAF00003950002 cram 543.1 MB
EGAF00003950003 cram 582.8 MB
EGAF00003950004 cram 600.9 MB
EGAF00003950005 cram 575.8 MB
EGAF00003950006 cram 578.6 MB
EGAF00003950007 cram 570.8 MB
EGAF00003950008 cram 706.7 MB
EGAF00003950009 cram 632.1 MB
EGAF00003950010 cram 638.2 MB
EGAF00003950011 cram 659.4 MB
EGAF00003950012 cram 632.1 MB
EGAF00003950013 cram 629.5 MB
EGAF00003950014 cram 628.7 MB
EGAF00003950015 cram 645.6 MB
EGAF00003950016 cram 675.6 MB
EGAF00003950017 cram 692.9 MB
EGAF00003950018 cram 621.4 MB
EGAF00003950019 cram 670.8 MB
EGAF00003950020 cram 668.0 MB
EGAF00003950021 cram 670.4 MB
EGAF00003950022 cram 679.6 MB
EGAF00003950023 cram 624.7 MB
EGAF00003950024 cram 673.8 MB
EGAF00003950025 cram 694.6 MB
EGAF00003950026 cram 632.8 MB
EGAF00003950027 cram 618.2 MB
EGAF00003950028 cram 728.1 MB
EGAF00003950029 cram 623.3 MB
EGAF00003950030 cram 642.0 MB
EGAF00003950031 cram 624.2 MB
EGAF00003950032 cram 686.5 MB
EGAF00003950033 cram 666.5 MB
EGAF00003950034 cram 622.9 MB
EGAF00003950035 cram 675.9 MB
EGAF00003950036 cram 701.9 MB
EGAF00003950037 cram 628.3 MB
EGAF00003950038 cram 657.4 MB
EGAF00003950039 cram 666.4 MB
EGAF00003950040 cram 707.7 MB
EGAF00003950041 cram 681.0 MB
EGAF00003950042 cram 649.9 MB
EGAF00003950043 cram 705.7 MB
EGAF00003950044 cram 723.5 MB
EGAF00003950045 cram 763.9 MB
EGAF00003950046 cram 710.8 MB
EGAF00003950047 cram 656.2 MB
EGAF00003950048 cram 700.5 MB
EGAF00003950049 cram 684.6 MB
EGAF00003950050 cram 659.3 MB
EGAF00003950051 cram 718.8 MB
EGAF00003950052 cram 742.7 MB
EGAF00003950053 cram 692.1 MB
EGAF00003950054 cram 715.6 MB
EGAF00003950055 cram 678.0 MB
EGAF00003950056 cram 447.8 MB
EGAF00003950057 cram 457.1 MB
EGAF00003950058 cram 460.3 MB
EGAF00003950059 cram 450.0 MB
EGAF00003950060 cram 494.0 MB
EGAF00003950061 cram 483.2 MB
EGAF00003950062 cram 447.3 MB
EGAF00003950063 cram 457.0 MB
EGAF00003950064 cram 476.8 MB
EGAF00003950065 cram 433.4 MB
EGAF00003950066 cram 457.3 MB
EGAF00003950067 cram 508.2 MB
EGAF00003950068 cram 472.0 MB
EGAF00003950069 cram 570.6 MB
EGAF00003950070 cram 458.7 MB
EGAF00003950071 cram 477.8 MB
EGAF00003950072 cram 449.9 MB
EGAF00003950073 cram 513.9 MB
EGAF00003950074 cram 509.3 MB
EGAF00003950075 cram 538.3 MB
EGAF00003950076 cram 516.9 MB
EGAF00003950077 cram 552.1 MB
EGAF00003950078 cram 520.8 MB
EGAF00003950079 cram 556.5 MB
EGAF00003950080 cram 523.9 MB
EGAF00003950081 cram 497.6 MB
EGAF00003950082 cram 552.1 MB
EGAF00003950083 cram 530.7 MB
EGAF00003950084 cram 528.2 MB
EGAF00003950085 cram 530.8 MB
EGAF00003950086 cram 514.3 MB
EGAF00003950087 cram 555.0 MB
EGAF00003950088 cram 548.6 MB
EGAF00003950089 cram 511.6 MB
EGAF00003950090 cram 542.1 MB
EGAF00003950091 cram 606.9 MB
EGAF00003950092 cram 583.4 MB
EGAF00003950093 cram 629.1 MB
EGAF00003950094 cram 624.7 MB
EGAF00003950095 cram 618.7 MB
EGAF00003950096 cram 595.8 MB
EGAF00003950097 cram 550.0 MB
EGAF00003950098 cram 583.0 MB
EGAF00003950099 cram 599.8 MB
EGAF00003950100 cram 617.8 MB
EGAF00003950101 cram 648.2 MB
EGAF00003950102 cram 568.5 MB
EGAF00003950103 cram 618.0 MB
EGAF00003950104 cram 577.5 MB
EGAF00003950105 cram 608.1 MB
EGAF00003950106 cram 469.2 MB
EGAF00003950107 cram 693.4 MB
EGAF00003950108 cram 662.8 MB
EGAF00003950109 cram 629.0 MB
EGAF00003950110 cram 658.8 MB
EGAF00003950111 cram 717.7 MB
EGAF00003950112 cram 684.5 MB
EGAF00003950113 cram 645.3 MB
EGAF00003950114 cram 694.2 MB
EGAF00003950115 cram 714.9 MB
EGAF00003950116 cram 685.4 MB
EGAF00003950117 cram 650.5 MB
EGAF00003950118 cram 690.2 MB
EGAF00003950119 cram 703.9 MB
EGAF00003950120 cram 739.5 MB
EGAF00003950121 cram 745.7 MB
EGAF00003950122 cram 697.0 MB
EGAF00003950123 cram 609.6 MB
EGAF00003950124 cram 616.8 MB
EGAF00003950125 cram 580.5 MB
EGAF00003950126 cram 548.9 MB
EGAF00003950127 cram 575.5 MB
EGAF00003950128 cram 612.3 MB
EGAF00003950129 cram 628.3 MB
EGAF00003950130 cram 578.0 MB
EGAF00003950131 cram 660.9 MB
EGAF00003950132 cram 557.5 MB
EGAF00003950133 cram 570.3 MB
EGAF00003950134 cram 601.2 MB
EGAF00003950135 cram 580.0 MB
EGAF00003950136 cram 645.7 MB
EGAF00003950137 cram 592.6 MB
EGAF00003950138 cram 615.3 MB
EGAF00003950139 cram 590.7 MB
EGAF00003950140 cram 699.6 MB
EGAF00003950141 cram 686.6 MB
EGAF00003950142 cram 629.8 MB
EGAF00003950143 cram 628.9 MB
EGAF00003950144 cram 615.2 MB
EGAF00003950145 cram 660.5 MB
EGAF00003950146 cram 646.1 MB
EGAF00003950147 cram 665.8 MB
EGAF00003950148 cram 734.7 MB
EGAF00003950149 cram 724.4 MB
EGAF00003950150 cram 589.0 MB
EGAF00003950151 cram 663.1 MB
EGAF00003950152 cram 670.4 MB
EGAF00003950153 cram 698.4 MB
EGAF00003950154 cram 659.3 MB
EGAF00003950155 cram 644.1 MB
EGAF00003950156 cram 781.3 MB
EGAF00003950157 cram 645.8 MB
EGAF00003950158 cram 620.5 MB
EGAF00003950159 cram 697.6 MB
EGAF00003950160 cram 653.0 MB
EGAF00003950161 cram 665.2 MB
EGAF00003950162 cram 672.8 MB
EGAF00003950163 cram 644.9 MB
EGAF00003950164 cram 761.9 MB
EGAF00003950165 cram 730.9 MB
EGAF00003950166 cram 624.3 MB
EGAF00003950167 cram 695.6 MB
EGAF00003950168 cram 697.8 MB
EGAF00003950169 cram 724.2 MB
EGAF00003950170 cram 688.9 MB
EGAF00003950171 cram 695.1 MB
EGAF00003950172 cram 728.5 MB
EGAF00003950173 cram 630.2 MB
EGAF00003950174 cram 602.8 MB
EGAF00003950175 cram 642.2 MB
EGAF00003950176 cram 662.3 MB
EGAF00003950177 cram 676.6 MB
EGAF00003950178 cram 652.2 MB
EGAF00003950179 cram 652.7 MB
EGAF00003950180 cram 725.7 MB
EGAF00003950181 cram 641.2 MB
EGAF00003950182 cram 602.6 MB
EGAF00003950183 cram 647.7 MB
EGAF00003950184 cram 642.3 MB
EGAF00003950185 cram 696.8 MB
EGAF00003950186 cram 650.1 MB
EGAF00003950187 cram 626.2 MB
EGAF00003950188 cram 818.9 MB
EGAF00003950189 cram 753.5 MB
EGAF00003950190 cram 683.5 MB
EGAF00003950191 cram 673.7 MB
EGAF00003950192 cram 752.1 MB
EGAF00003950193 cram 705.0 MB
EGAF00003950194 cram 687.0 MB
EGAF00003950195 cram 762.2 MB
EGAF00003950196 cram 773.7 MB
EGAF00003950197 cram 699.7 MB
EGAF00003950198 cram 662.2 MB
EGAF00003950199 cram 689.1 MB
EGAF00003950200 cram 719.7 MB
EGAF00003950201 cram 725.6 MB
EGAF00003950202 cram 724.1 MB
EGAF00003950203 cram 762.8 MB
EGAF00003950204 cram 733.0 MB
EGAF00003950205 cram 633.5 MB
EGAF00003950206 cram 616.4 MB
EGAF00003950207 cram 683.7 MB
EGAF00003950208 cram 736.4 MB
EGAF00003950209 cram 746.9 MB
EGAF00003950210 cram 721.1 MB
EGAF00003950211 cram 729.2 MB
EGAF00003950212 cram 774.7 MB
EGAF00003950213 cram 672.5 MB
EGAF00003950214 cram 623.4 MB
EGAF00003950215 cram 670.0 MB
EGAF00003950216 cram 704.0 MB
EGAF00003950217 cram 668.8 MB
EGAF00003950218 cram 670.0 MB
EGAF00003950219 cram 684.0 MB
EGAF00003950220 cram 698.3 MB
EGAF00003950221 cram 672.5 MB
EGAF00003950222 cram 715.5 MB
EGAF00003950223 cram 651.7 MB
EGAF00003950224 cram 647.6 MB
EGAF00003950225 cram 652.3 MB
EGAF00003950226 cram 640.3 MB
EGAF00003950227 cram 647.9 MB
EGAF00003950228 cram 704.1 MB
EGAF00003950229 cram 712.6 MB
EGAF00003950230 cram 719.7 MB
EGAF00003950231 cram 686.4 MB
EGAF00003950232 cram 674.3 MB
EGAF00003950233 cram 687.7 MB
EGAF00003950234 cram 660.8 MB
EGAF00003950235 cram 641.8 MB
EGAF00003950236 cram 675.8 MB
EGAF00003950237 cram 766.7 MB
EGAF00003950238 cram 691.4 MB
EGAF00003950239 cram 625.2 MB
EGAF00003950240 cram 678.0 MB
EGAF00003950241 cram 666.3 MB
EGAF00003950242 cram 702.6 MB
EGAF00003950243 cram 669.0 MB
EGAF00003950244 cram 738.3 MB
EGAF00003950245 cram 718.1 MB
EGAF00003950246 cram 724.3 MB
EGAF00003950247 cram 625.0 MB
EGAF00003950248 cram 692.4 MB
EGAF00003950249 cram 654.8 MB
EGAF00003950250 cram 651.9 MB
EGAF00003950251 cram 681.7 MB
EGAF00003950252 cram 780.6 MB
EGAF00003950253 cram 700.1 MB
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EGAF00003951311 cram 709.3 MB
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EGAF00003951313 cram 710.8 MB
EGAF00003951314 cram 619.1 MB
EGAF00003951315 cram 680.7 MB
EGAF00003951316 cram 614.3 MB
EGAF00003951317 cram 594.7 MB
EGAF00003951318 cram 621.7 MB
EGAF00003951319 cram 600.9 MB
EGAF00003951320 cram 610.4 MB
EGAF00003951321 cram 578.0 MB
EGAF00003951322 cram 571.7 MB
EGAF00003951323 cram 656.0 MB
EGAF00003951324 cram 619.1 MB
EGAF00003951325 cram 606.6 MB
EGAF00003951326 cram 600.5 MB
EGAF00003951327 cram 589.2 MB
EGAF00003951328 cram 646.9 MB
EGAF00003951329 cram 585.5 MB
EGAF00003951330 cram 600.3 MB
EGAF00003951331 cram 630.5 MB
EGAF00003951332 cram 602.7 MB
EGAF00003951333 cram 703.2 MB
EGAF00003951334 cram 691.3 MB
EGAF00003951335 cram 695.4 MB
EGAF00003951336 cram 751.8 MB
EGAF00003951337 cram 704.1 MB
EGAF00003951338 cram 687.5 MB
EGAF00003951339 cram 731.8 MB
EGAF00003951340 cram 765.5 MB
EGAF00003951341 cram 666.5 MB
EGAF00003951342 cram 718.9 MB
EGAF00003951343 cram 749.3 MB
EGAF00003951344 cram 691.5 MB
EGAF00003951345 cram 720.1 MB
EGAF00003951346 cram 724.3 MB
EGAF00003951347 cram 738.1 MB
EGAF00003951348 cram 710.5 MB
EGAF00003951349 cram 693.7 MB
EGAF00003951350 cram 616.4 MB
EGAF00003951351 cram 636.2 MB
EGAF00003951352 cram 625.1 MB
EGAF00003951353 cram 631.8 MB
EGAF00003951354 cram 647.9 MB
EGAF00003951355 cram 686.9 MB
EGAF00003951356 cram 691.9 MB
EGAF00003951357 cram 632.0 MB
EGAF00003951358 cram 655.6 MB
EGAF00003951359 cram 702.8 MB
EGAF00003951360 cram 640.2 MB
EGAF00003951361 cram 633.4 MB
EGAF00003951362 cram 622.0 MB
EGAF00003951363 cram 724.1 MB
EGAF00003951364 cram 686.7 MB
EGAF00003951365 cram 667.2 MB
EGAF00003951366 cram 677.9 MB
EGAF00003951367 cram 762.1 MB
EGAF00003951368 cram 704.0 MB
EGAF00003951369 cram 728.7 MB
EGAF00003951370 cram 713.3 MB
EGAF00003951371 cram 824.8 MB
EGAF00003951372 cram 732.8 MB
EGAF00003951373 cram 744.1 MB
EGAF00003951374 cram 745.9 MB
EGAF00003951375 cram 744.0 MB
EGAF00003951376 cram 727.2 MB
EGAF00003951377 cram 747.5 MB
EGAF00003951378 cram 726.5 MB
EGAF00003951379 cram 633.5 MB
EGAF00003951380 cram 637.8 MB
EGAF00003951381 cram 571.4 MB
EGAF00003951382 cram 622.6 MB
EGAF00003951383 cram 645.6 MB
EGAF00003951384 cram 625.4 MB
EGAF00003951385 cram 618.3 MB
EGAF00003951386 cram 625.5 MB
EGAF00003951387 cram 655.2 MB
EGAF00003951388 cram 664.2 MB
EGAF00003951389 cram 620.2 MB
EGAF00003951390 cram 625.4 MB
EGAF00003951391 cram 664.6 MB
EGAF00003951392 cram 628.1 MB
EGAF00003951393 cram 674.4 MB
EGAF00003951394 cram 632.6 MB
EGAF00003951395 cram 644.5 MB
EGAF00003952336 cram 5.6 GB
EGAF00003952337 cram 5.6 GB
EGAF00003952338 cram 5.6 GB
EGAF00003952339 cram 5.6 GB
EGAF00003952340 cram 5.6 GB
EGAF00003952341 cram 5.5 GB
EGAF00003952342 cram 5.5 GB
EGAF00003952343 cram 5.5 GB
EGAF00003952344 cram 5.9 GB
EGAF00003952345 cram 5.8 GB
EGAF00003952346 cram 5.7 GB
EGAF00003952347 cram 6.2 GB
EGAF00003952348 cram 5.9 GB
EGAF00003952349 cram 5.8 GB
EGAF00003952350 cram 5.8 GB
EGAF00003952351 cram 6.2 GB
EGAF00003952352 cram 5.9 GB
EGAF00003952353 cram 5.8 GB
EGAF00003952354 cram 5.8 GB
EGAF00003952355 cram 6.2 GB
EGAF00003952356 cram 5.9 GB
EGAF00003952357 cram 5.8 GB
EGAF00003952358 cram 5.7 GB
EGAF00003952359 cram 6.2 GB
EGAF00003952360 cram 5.8 GB
EGAF00003952361 cram 5.8 GB
EGAF00003952362 cram 5.7 GB
EGAF00003952363 cram 6.2 GB
EGAF00003952364 cram 5.9 GB
EGAF00003952365 cram 5.8 GB
EGAF00003952366 cram 5.8 GB
EGAF00003952367 cram 6.2 GB
EGAF00003952368 cram 5.9 GB
EGAF00003952369 cram 5.8 GB
EGAF00003952370 cram 5.8 GB
EGAF00003952371 cram 6.2 GB
EGAF00003952372 cram 5.9 GB
EGAF00003952373 cram 5.8 GB
EGAF00003952374 cram 5.8 GB
EGAF00003952375 cram 6.2 GB
EGAF00003952376 cram 5.3 GB
EGAF00003952377 cram 5.2 GB
EGAF00003952378 cram 5.3 GB
EGAF00003952379 cram 5.2 GB
EGAF00003952380 cram 5.3 GB
EGAF00003952381 cram 5.3 GB
EGAF00003952382 cram 5.3 GB
EGAF00003952383 cram 5.4 GB
EGAF00003952384 cram 5.9 GB
EGAF00003952385 cram 6.6 GB
EGAF00003952386 cram 6.5 GB
EGAF00003952387 cram 6.4 GB
EGAF00003952388 cram 6.9 GB
EGAF00003952389 cram 5.8 GB
EGAF00003952390 cram 10.7 GB
EGAF00003952391 cram 9.8 GB
EGAF00003952392 cram 10.7 GB
EGAF00003952393 cram 10.6 GB
EGAF00003952394 cram 9.8 GB
EGAF00003952395 cram 10.6 GB
EGAF00003952396 cram 10.7 GB
EGAF00003952397 cram 9.7 GB
EGAF00003952398 cram 10.7 GB
EGAF00003952399 cram 10.9 GB
EGAF00003952400 cram 10.0 GB
EGAF00003952401 cram 10.9 GB
EGAF00003952402 cram 11.2 GB
EGAF00003952403 cram 10.9 GB
EGAF00003952404 cram 11.0 GB
EGAF00003952405 cram 10.9 GB
EGAF00003952406 cram 11.8 GB
EGAF00003952407 cram 10.7 GB
EGAF00003952408 cram 11.6 GB
EGAF00003952409 cram 10.7 GB
EGAF00003952410 cram 11.6 GB
EGAF00003952411 cram 10.7 GB
EGAF00003952412 cram 11.5 GB
EGAF00003952413 cram 10.7 GB
EGAF00003952414 cram 11.0 GB
EGAF00003952415 cram 10.8 GB
EGAF00003952416 cram 10.8 GB
EGAF00003952417 cram 11.0 GB
EGAF00003952418 cram 10.0 GB
EGAF00003952419 cram 10.0 GB
EGAF00003952420 cram 9.9 GB
EGAF00003952421 cram 9.9 GB
EGAF00003952422 cram 24.8 GB
EGAF00003952423 cram 14.2 GB
EGAF00003952424 cram 23.6 GB
EGAF00003952425 cram 20.4 GB
EGAF00003952426 cram 23.3 GB
EGAF00003952427 cram 25.4 GB
EGAF00003952428 cram 28.9 GB
EGAF00003952429 cram 14.5 GB
EGAF00003952430 cram 17.3 GB
EGAF00003952431 cram 31.4 GB
EGAF00003952432 cram 16.7 GB
EGAF00003952433 cram 25.7 GB
EGAF00003952434 cram 26.7 GB
EGAF00003952435 cram 25.8 GB
EGAF00003952436 cram 16.4 GB
EGAF00003952437 cram 16.9 GB
EGAF00003952438 cram 31.0 GB
EGAF00003952439 cram 13.6 GB
EGAF00003952440 cram 24.7 GB
EGAF00003952441 cram 24.4 GB
EGAF00003952442 cram 17.6 GB
EGAF00003952443 cram 13.3 GB
EGAF00003952444 cram 14.5 GB
EGAF00003952445 cram 24.4 GB
EGAF00003952446 cram 25.4 GB
EGAF00003952447 cram 15.6 GB
EGAF00003952448 cram 16.3 GB
EGAF00003952449 cram 17.6 GB
EGAF00003952450 cram 19.7 GB
EGAF00003952451 cram 18.9 GB
EGAF00003952452 cram 17.8 GB
EGAF00003952453 cram 21.5 GB
EGAF00003952454 cram 25.1 GB
EGAF00003952455 cram 23.0 GB
EGAF00003952456 cram 26.5 GB
EGAF00003952457 cram 21.7 GB
EGAF00003952458 cram 29.3 GB
EGAF00003952459 cram 22.9 GB
EGAF00003952460 cram 22.9 GB
EGAF00003952461 cram 21.6 GB
EGAF00003952462 cram 19.6 GB
EGAF00003952463 cram 20.2 GB
EGAF00003952464 cram 19.4 GB
EGAF00003952465 cram 19.5 GB
EGAF00003952466 cram 21.0 GB
EGAF00003952467 cram 17.7 GB
EGAF00003952468 cram 20.7 GB
EGAF00003952469 cram 23.5 GB
EGAF00003952470 cram 22.6 GB
EGAF00003952471 cram 20.6 GB
EGAF00003952472 cram 18.3 GB
EGAF00003952473 cram 19.9 GB
EGAF00003952474 cram 19.9 GB
1780 Files (2.8 TB)