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Oncogenic gene fusions in primary colon cancers

This study represents RNA-sequencing data from 278 primary colon cancers obtained from fresh-frozen tumor sections. The project goal was to identify novel oncogenic gene fusions in these data. In addition, we studied the detected gene fusions at the molecular level and defined their effects on downstream pathways.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001003291 Illumina HiSeq 2500 NextSeq 500 278
Publications Citations
Gene length corrected trimmed mean of M-values (GeTMM) processing of RNA-seq data performs similarly in intersample analyses while improving intrasample comparisons.
BMC Bioinformatics 19: 2018 236
67
Interconnectivity between molecular subtypes and tumor stage in colorectal cancer.
BMC Cancer 20: 2020 850
13
A panel of DNA methylation markers for the classification of consensus molecular subtypes 2 and 3 in patients with colorectal cancer.
Mol Oncol 15: 2021 3348-3362
4
Molecular characterization of colorectal cancer related peritoneal metastatic disease.
Nat Commun 13: 2022 4443
16