Profiling heterogeneity in Human derived IPSC neurons
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
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The impact of genetic variants on molecular pathways that give rise to neurodegenerative diseases such as Alzheimer's and Parkinson's is best elucidated in the appropriate cell types and molecular contexts. Existing studies have focused on bulk profiling of mixed cell types, but have ignored assaying genetic effects across development and cell differentiation. At the core of this proposal is the idea to use single-cell assays to study genetic effects during differentiation of dopaminergic and ... (Show More)
|Illumina HiSeq 4000||42|