ChIP-seq data of H3K4me3, H3K27ac and H3K27me3 on multiple human embryonic tissues.

Study

Study ID	Alternative Stable ID	Type
EGAS00001003163		Other

Study Description

The regulatory landscape of the human genome during organogenesis is undescribed for most tissues. We used ChIP-seq to survey histone modifications in 13 human embryonic tissues. We describe patterns of both common and tissue-specific marking of promoter activation and repression and use enhancer usage to infer regulatory pathways.

Study Datasets 1 dataset.

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Dataset ID	Description	Technology	Samples
EGAD00001004335	Histone ChIP-seq of 13 human embryonic tissues from weeks 6-8 of gestation. H3K4me3, H3K27me3 and H3K27ac. Biological replicates (n=2) for 11 tissues. Tissues (n): Brain (2); Retinal Pigmented Epithelium (eye)(2); Palate(2); Tongue (1); Left ventricle (heart)(2); Lung(2); Liver(2); Pancreas (2); Stomach(1); Upper limb (2); Lower limb (2); Adrenal gland (2); Kidney (2) Histone ChIP-seq of 13 human embryonic tissues from weeks 6-8 of gestation. H3K4me3, H3K27me3 and H3K27ac. Biological replicates (n=2) for 11 tissues. Tissues (n): Brain (2); Retinal Pigmented Epithelium (eye)(2); Palate(2); Tongue (1); Left ventricle (heart)(2); Lung(2); Liver(2); Pancreas (2); Stomach(1); Upper limb (2); Lower limb (2); Adrenal gland (2); Kidney (2)	Illumina HiSeq 2500,Illumina HiSeq 4000	77

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