Study

Primary breast tumor heterogeneity through therapy

Study ID Alternative Stable ID Type
EGAS00001003168 Cancer Genomics

Study Description

NA

Study Datasets 2 datasets.

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Dataset ID Description Technology Samples
EGAD00001004306
We performed whole-exome sequencing on multiple regions (n=2-3) from four primary untreated breast tumors (n=1 HER2+, n=2 ER+/HER2-, n=1 triple-negative), as well as matched normal. We also performed whole-exome sequencing on one region from the pre-treatment diagnostic core biopsy and multiple regions (n=2-6) from the post-treatment surgical specimen for five HER2+ primary breast tumors, as well as matched normal; all were treated with combination chemotherapy and trastuzumab. Analysis of ... (Show More)
Illumina HiSeq 2500 42
EGAD00001004896
In order to reconstruct the evolutionary history of metastatic colorectal cancer, we performed whole-exome sequencing of 12 metastatic colorectal cancer patients for whom the primary tumor and matched distant metastases to the brain (n=10) and liver (n=2). For 8 of the 12 patients, multiple regions (n=3-7) of the primary tumor and distant metastases were sequenced.
Illumina HiSeq 2000,Illumina HiSeq 2500 163

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