Study

Characterizing the immune and genome landscapes for osteosarcoma

Study ID Alternative Stable ID Type
EGAS00001003247 Other

Study Description

Osteosarcoma have heavily rearranged genomes and moderate tumor mutation burden, which suggests that the patients may express neoantigens that could be targeted by immune cells. To characterize the immunogenomic landscape of this disease, we performed genome, transcriptome, immune and proteomic profiling of 48 patients comprised largely of relapsed and metastatic cases from both pediatric and adult patients.

Study Datasets 2 datasets.

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Dataset ID Description Technology Samples
EGAD00001008435
This dataset contains 86 osteosarcoma samples and their matched normals that underwent RNA sequencing using size fractionation, NuGEN Ovation Ultralow Library System V2 preparation, and paired-end sequencing on Illumina HiSeq 2000.
Illumina HiSeq 2000 1
EGAD00001008436
This dataset contains 86 osteosarcoma samples and their matched normals that underwent RNA sequencing using size fractionation, NuGEN Ovation Ultralow Library System V2 preparation, and paired-end sequencing on Illumina HiSeq 2000.
Illumina HiSeq 2000 1

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