Adeno-associated virus in the liver: natural history and consequences in tumor development
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
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Adeno-associated virus (AAV) is a defective mono-stranded DNA virus, endemic in human population (35-80%). Recurrent clonal AAV2 insertions are associated with the pathogenesis of rare human hepatocellular carcinoma (HCC) developed on normal liver. This study aimed to characterize the natural history of AAV infection in the liver and its consequence in tumor development. In silico analyses using viral capture data explored viral variants and new clonal insertions. Clonal AAV insertions were ... (Show More)
|Illumina HiSeq 2000||20|