Study

MutWP5 CRUK Mutographs of Cancer Breast BRCA Carriers Targeted

Study ID Alternative Stable ID Type
EGAS00001003315 Cancer Genomics

Study Description

Sequencing of LCM-derived microbiopsies from 20 women who underwent risk-reducing reduction mastectomies due to germline BRCA1/2. Goal to assess the mutational burden, spectrum, and clonal dynamics within the tissue. Targeted data will be used as a driver and clonality screen, highly clonal or driver-containing samples will subsequently be sent for whole-genome sequencing. Results from this portion of the study will be compared to women who had cosmetic breast reduction surgeries and those with cancer.

Study Datasets 1 dataset.

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Dataset ID Description Technology Samples
EGAD00001005920
Sequencing of LCM-derived microbiopsies from 20 women who underwent risk-reducing reduction mastectomies due to germline BRCA1/2. Goal to assess the mutational burden, spectrum, and clonal dynamics within the tissue. Targeted data will be used as a driver and clonality screen, highly clonal or driver-containing samples will subsequently be sent for whole-genome sequencing. Results from this portion of the study will be compared to women who had cosmetic breast reduction surgeries and those with ... (Show More)
Illumina HiSeq 4000 49

Who archives the data?

There are no publications available