Genome Wide Association Study:GR@ACE Stage I
The Genome Research program at Fundacio ACE (GR@ACE, Barcelona, Spain), represents a new effort to study Alzheimer's Disease susceptibility. The GR@ACE study comprises 7,409 unrelated individuals. 4,120 AD cases were diagnosed at Fundació ACE Memory Clinic (Barcelona, Spain). 3,289 Controls were obtained from three collections (Fundació ACE, Barcelona; DNA National Biobank, Salamanca and HU Valme, Seville). Genotyping was carried out using the 815K Axiom Spain Biobank array (Affymetrix.) in the Spanish national center for genotyping (CEGEN, Santiago de Compostela, Spain). After genotyping, an extensive quality control was conducted, including re-sampling, gender match, stratification, relatedness, heterozygosity, differential missingness and HWD analyses.
- Type: Other
- Archiver: European Genome-Phenome Archive (EGA)
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Dataset ID | Description | Technology | Samples |
---|---|---|---|
EGAD00010001653 | Axiom 815K Spanish Biobank array | 7409 | |
EGAD00010001654 | Axiom 815K Spanish Biobank array | 7409 | |
EGAD00010001655 | Axiom 815K Spanish Biobank array | 7409 |
Publications | Citations |
---|---|
The <i>MAPT</i> H1 Haplotype Is a Risk Factor for Alzheimer's Disease in <i>APOE</i> ε4 Non-carriers.
Front Aging Neurosci 11: 2019 327 |
24 |
Long runs of homozygosity are associated with Alzheimer's disease.
Transl Psychiatry 11: 2021 142 |
6 |
What does heritability of Alzheimer's disease represent?
PLoS One 18: 2023 e0281440 |
12 |
Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews.
Alzheimers Dement 19: 2023 5550-5562 |
2 |